Oral presentation
26
ALKALOIDS FROM Delphinium oreophilum
H.I. Ahunova
1
, Kh.M. Bobakulov
2
, B. Tashkhodzhaev
2
,
N.I. Mukarramov
2
, Sh.V. Abdullaev
1
1) Namangan State University, Namangan, Uzbekistan,
e-mail: ahunova.hilola@yandex.ru
2) S.Yu. Yunusov Institute of the Chemistry of Plant Substances Academy of sciences of
the Republic of Uzbekistan st. Mirzo-Ulugbek, 77, 100170 Tashkent
e-mail: khayrulla@rambler.ru
There are about 350 plant species of the genus
Delphinium
(family
Ranunculaceae
)
in the world, of which 22 species are found in Uzbekistan and contain mainly diterpene
alkaloids, some of which have valuable pharmacological properties.
Delphinium oreophilum
Huth is a perennial plant 30-60 cm high,
growing in the
mountain ranges of the Zamin and Yangikorgan regions of Uzbekistan [1]. Earlier we
studied the composition of
D.oreophilum
-
essential oils, macro- and microelements.
[2].
In our next work, we studied the alkaloid content of the aerial part of
D. oreophilum
collected during flowering in Zamin region.
In the course of the study, well-known
alkaloids were isolated: diterpenoid alkaloids delphatine
(1)
, 14-acetyldelectinine
(2)
,
browniine
(3)
, 14-acetylbrowniine
(4)
[3] and delavaine B
(5)
. Along with them, the
amide 4-{[2-(methoxycarbonyl)phenyl]amino}-2-methyl-4-oxobutanoic acid
(6)
and
isoboldine
(7)
were also isolated. Among the above compounds
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