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Oral presentation  26  ALKALOIDS FROM Delphinium oreophilum



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Abstracts ICPS 2023

 


Oral presentation 
26 
ALKALOIDS FROM Delphinium oreophilum 
H.I. Ahunova
1
, Kh.M. Bobakulov
2
, B. Tashkhodzhaev
2

N.I. Mukarramov
2
, Sh.V. Abdullaev

1) Namangan State University, Namangan, Uzbekistan, 
e-mail: ahunova.hilola@yandex.ru 
2) S.Yu. Yunusov Institute of the Chemistry of Plant Substances Academy of sciences of 
the Republic of Uzbekistan st. Mirzo-Ulugbek, 77, 100170 Tashkent 
e-mail: khayrulla@rambler.ru 
There are about 350 plant species of the genus 
Delphinium
(family 
Ranunculaceae

in the world, of which 22 species are found in Uzbekistan and contain mainly diterpene 
alkaloids, some of which have valuable pharmacological properties. 
Delphinium oreophilum 
Huth is a perennial plant 30-60 cm high, growing in the 
mountain ranges of the Zamin and Yangikorgan regions of Uzbekistan [1]. Earlier we 
studied the composition of 
D.oreophilum
- essential oils, macro- and microelements. 
[2]. 
In our next work, we studied the alkaloid content of the aerial part of 
D. oreophilum
collected during flowering in Zamin region. In the course of the study, well-known 
alkaloids were isolated: diterpenoid alkaloids delphatine 
(1)
, 14-acetyldelectinine 
(2)

browniine 
(3)
, 14-acetylbrowniine 
(4)
[3] and delavaine B 
(5)
. Along with them, the 
amide 4-{[2-(methoxycarbonyl)phenyl]amino}-2-methyl-4-oxobutanoic acid 
(6)
and 
isoboldine 
(7)
were also isolated. Among the above compounds 

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