Poster presentation
328
OBTAINING DRY EXTRACTS BY SPRAY DRYING FOR THE
DEVELOPMENT OF ANTIHYPERTENSIVE DRUGS
D.T. Safarova
Tashkent Pharmaceutical Institute Tashkent, Uzbekistan
For the treatment and prevention of hypertension, there are also drugs based on
medicinal
plant materials, prepared in various combinations and increasing their
pharmacological efficacy. In this regard, it is important to
expand the range of drugs
with high therapeutic efficacy, harmless and affordable, produced on the basis of plant
materials at domestic pharmaceutical enterprises.
The aim of the study is to develop antihypertensive drugs (extracts for further
preparation of the balm) based on medicinal plant materials. Peppermint leaves (folium
Menthae piperitae
L.), rhizomes with roots of valerian (rhizoma et radicis
Valerianae
officinalis
L.), rose hips (fructus
Rosae cinnamomae
L.),
aerial parts of lemon balm
(herba
Melissae officinalis
L.), motherwort herb (herba
Leonuri cardiacae
L.S.L.), corn
stigmas (
Styli cum Stigmatis Zeae maydis
L.), and blood-red hawthorn fruit (fructus
Crataegus sanguineae
Pall).
Table
Saw drying temperature at the inlet
of medicinal herbs extracts
№
Name of extract
Spray drying inlet
temperature
1
Motherwort herb extract - Extractum herbae Leonuri
1800 С
2
Peppermint Leaf
Extract - Extractum Menthae
1850 С
3
Corn Stigma Extract - Extractum Styli cum Stigmatis
Zeae
165 0С
4
Blood red hawthorn fruit extract - Extractum fructus
Crataegus
1890 С
5
rose hips extract - Extractum fructus Rosae
1720 С
6
Melissa leaf extract - Extractum folium Melissae
1900 С
7
Rhizome extract with roots
of valerian officinalis-
Extractum rhizomatis et radicis Valerianae
1850 С
As a result of the research, dry extracts were obtained from
the dark extracts obtained
from the above plant raw materials using MCGS-5 L spray drying equipment. The
obtained dry extracts were evaluated from a technological point of view.
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