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Abstracts ICPS 2023

Acknowledgment
The Ministry of Education and Science of the Republic of Kazakhstan (AP09259567) 
supported this work.
 
References 
1.
Safaeian L., Ghannadi A., Javanmard S.H., Vahidian M.H., 2015. The effect of 
hydroalcoholic extract of 
Ferula foetida
stems on blood pressure and oxidative 
stress in dexamethasone-induced hypertensive rats. Research in Pharmaceutical 
Sciences, 10 (4), 326-334. 
2.
Gundamaraju R., 2013. Evaluation of anti-helmintic activity of 
Ferula foetida
“Hing- A natural Indian spice” aqueous extract. Asian Pacific Journal of 
Tropical Disease, 3(3), 189-191. 
 
 


Poster presentation 
340 
CHEMICAL COMPOSITION OF THE PLANT PRANGOS 
PABULARIA GROWING IN THE SOUTH OF KYRGYZSTAN 
 
Mamyt kyzy Kyzsaykal, Talantbek kyzy Tamara, Zyinat Boronova, Bakyt 
Keneshov
 
OSHSUOsh, Kyrgyzstan 
e.mail:keneshovbakyt@mail.com 
Annotation:
In the southern region of Kyrgyzstan, the plant Prangos pabularia is
widely distributed, and has a valuable forage, medicinal, honey-bearing, soil-protective 
and water-regulating value. But the chemical composition is very poorly understood. 
Based on this, the roots of the Prangos pabularia plant after the growing season from the 
Kara-Shoro National Park of the Uzgen district were used as the object of research. As a 
result, two individual compounds were isolated and identified with previously isolated 
substances from plants of other species of the umbrella families. 
- Root extraction was carried out with ethanol.
- To isolate individual compounds, the following methods were used: fractionation 
by polarity, column chromatography (KX) using silica gel of the KSK brand as an 
adsorbent. 
- Fractions were collected in 20-100 ml, the uniformity and purity of the fraction was 
checked by thin-layer chromatography (TLC) on plates "SilifolUV-254" produced in 
Sweden in the hexane-ethyl acetate system. 
- The melting point was determined visually, the rotation angles were obtained on the 
polarimeter PolamatA. 
Conclusions:
1.
The coumarin composition of the roots of Prangos pobularia growing in the 
South of Kyrgyzstan has been studied. 
2.
As a result of studies of the chemical composition of prangos roots, 2 individual 
compounds were identified: substance I and substance II. 
3.
The physicochemical constants and chemical properties of the isolated substances 
were determined, as a result, they were identified with previously known 
compounds: substance I - karatavicin, substance II–fecalone. 

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