Anahtar kelimeler: Yoğun bakım, Hellp sendromu, obstetrik
Hellp Syndrome (Hemolysis-Elevated Liver enzymes-Low
Platelets)is characterized by hemolysis, elevated liver enzymes and
low platelet count, and related with an increased with an increased
foetal and maternal mortality. We aimed in this study to evaluate the
morbidity and mortality of 15 Hellp syndrome patients who have been
admitted to our intensive care unit, between 2005 and 2009 years
retrospectively. Patients ICU admission indications, demographic,
clinical and obstetric data was noted down; hemoglobin, serum
albumin level, prothrombine time ve active partial thromboplastin time,
fibrinogen level, thrombocyte number, total bilirubine ve creatinine
levels, AST, ALT, lactate dehidroginase (LDH) levels were analysed.
Intensive care unit(ICU)admission of Hellp sydrome patients
were convulsion, loss of consciousness, airway control, invasive
hemodinamic monitorisation, ARDS, intracerebral hemorrhage and
respiration insufficiency During 4 day intensive care unit following
of our patients, thrombocyte numbers began to increase from third
day of admission. But this increament was statistically significant
between admission day to ICU and fourth day. Again similarly AST,
ALT, LDH, ürea ve creatinine levels began to decreased at third
day and decreament was statistically significant as from fourth
day(P<0.05). Total bilirubin levels of our patients showed significant
decrease as from second day. Ten of the patients needed invasive
mechanical ventilation, 3 patients supported noninvasively with total
face mask. Plasmapheresis applied to 3 patients because of resistant
thrombocytopenia and acute renal failure. Only intracerebral
hemorrhage patient was died because of sepsis. As a result, Hellp
syndrome is one of the most frequent obstetric problems in ICU
and has an increased foetal and maternal mortality. Especially
Hellp Syndrome patients with convulsions whose clinics thought to
be worse after vaginal delivery or C/S admittance to 3. step ICU
may reduce complication rate and decrease mortality and morbidity.
Plasmapheresis application may decrease organ insufficiencies in
severe and resistant cases and increase clinical achievement .
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