Uperior vena cava syndrome (svcs) was first described in l757 in a patient with a syphilitic



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Lymphomas and metastatic tumors. 

The second

group of malignancies that commonly cause SVCS are

lymphomas, especially non-Hodgkin’s lymphoma. SVCS

occurs in 3% to 8% of patients with lymphoma. The lym-

phoma usually originates in the anterior mediastinum

and produces SVCS by external compression. Metastatic

tumors, more commonly breast and testicular tumors,

cause SVCS in approximately 5% to 20% of patients.

2–9


Benign Causes

Many benign disorders can cause SVCS (Table 2). As

noted previously, however, benign disorders account for

less than 10% of cases of SVCS. Benign causes of SVCS

include thymoma, cystic hygroma, benign cystic ter-

atoma, substernal thyroid goiter, dermoid cyst, and

postirradiation therapy. Infections notable for causing

SVCS are tuberculosis, histoplasmosis, actinomycosis,



S

Dr. Bhimji is a Resident in Cardiac Surgery, Medical College of Georgia,

Augusta, GA. 


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