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Lymphomas and metastatic tumors.
The second
group of malignancies that commonly cause SVCS are
lymphomas, especially non-Hodgkin’s lymphoma. SVCS
occurs in 3% to 8% of patients with lymphoma. The lym-
phoma usually originates in the anterior mediastinum
and produces SVCS by external compression. Metastatic
tumors, more commonly breast and testicular tumors,
cause SVCS in approximately 5% to 20% of patients.
2–9
Benign Causes
Many benign disorders can cause SVCS (Table 2). As
noted previously, however, benign disorders account for
less than 10% of cases of SVCS. Benign causes of SVCS
include thymoma, cystic hygroma, benign cystic ter-
atoma, substernal thyroid goiter, dermoid cyst, and
postirradiation therapy. Infections notable for causing
SVCS are tuberculosis, histoplasmosis, actinomycosis,
S
Dr. Bhimji is a Resident in Cardiac Surgery, Medical College of Georgia,
Augusta, GA.
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