Contrast venography.
The extent and site of ob-
struction as well as the nature of obstruction must be
identified when SVCS is diagnosed. Identification of
these features may be achieved by a number of radio-
logic imaging studies. Contrast venography can provide
information regarding the patency of the superior vena
cava, the degree of superior vena cava obstruction, and
the differentiation between intrinsic and extrinsic causi-
tive factors responsible for the obstruction. Contrast
venography also provides assessment of collateral vessel
formation, the degree of venous distension of the neck
and arms, measurement of actual venous pressure, and
the presence of the internal jugular vein reflux.
Contrast venography is essential prior to planning
any surgical bypass operation. Surgical bypass opera-
tions are easier to accomplish when the brachiocephal-
ic veins are not involved. However, if all the intra-
thoracic veins are obstructed, extrathoracic bypass oper-
ations can be undertaken, but the operation is more
technically difficult and the results are less favorable.
4
Contrast venography is also very helpful in docu-
menting obstructions caused by thrombus formation.
When thrombosis is present, treatment with fibrinolyt-
ic agents (eg, urokinase, streptokinase) is pursued and
repeat venography can be used to evaluate treatment
efficacy. In the rare cases in which fresh thrombosis is
detected in the superior vena cava, thromboembolec-
tomy may be an alternate method of treatment.
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