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INSULIN INJECTION
KNOW-HOW
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american association of diabetes educators
Supported by BD Diabetes Care
1
Congratulations for making the move to
insulin therapy. It won’t be long before you
start enjoying better blood sugar control,
more energy, and a host of other benefi ts.
The prospect of taking insulin
injections may have you feeling a
bit anxious. That’s OK! Just
about everyone feels that way.
Just know that your anxiety will
vanish soon enough. Here are
some valuable facts and tips to
help make your transition to
insulin smooth and easy.
WaYs to give insULin
Because insulin is broken down
by digestive enzymes, it cannot
be taken in pill form. Instead, it is
delivered with a syringe into the
layer of fat below the skin, also
called the “subcutaneous” tissue.
The layer of fat on the stomach,
hips, thighs, buttocks and backs of
the arms are common sites for
injecting insulin. From there, the
insulin absorbs into the blood-
stream where it circulates to the
cells throughout the body.
The really good news about deliver-
ing insulin into the layer of fat
below the skin is that there are no
nerve endings in this area,
so injections are usually
painless. There are a num-
ber of options for adminis-
tering insulin:
SYRINGES
Disposable plastic insulin
syringes are still widely
used, but the popularity
of pens and pumps (see
next page) is growing.
Syringes vary in terms of
how much insulin they hold as well
as the length and thickness of the
needle. Syringes can be used to
deliver insulin directly into the layer
of fat below the skin, or they can
inject insulin into a temporary
“port” that sits on the skin. The
port, which is changed every 2-3
days, features a small fl exible
plastic tube that sits below the skin.
A needle is used to place the tube
under the skin, so only one needle
stick is required every 2-3 days
when a port is used.
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INSULIN INJECTION
KNOW-HOW
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Learning how to inject insulin
Supported by BD Diabetes Care
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American Association of Diabetes Educators
insulin injection
know-how
learning how to
inject insulin
2
PENS
Insulin pens got their name because
they are about the size and shape
of a writing pen. They contain
insulin (instead of ink) and have a
dial for setting the dose. A dispos-
able pen needle is attached
to the end of the pen prior
to injecting. As was the case
with syringes, pen needles
are available in a variety of
lengths and thicknesses.
Because they cut down on
medical waste and are
considered by most to be
more convenient, accurate
and easy to use than
syringes, insulin pens are
growing in popularity
among people of all ages.
PUMPS
Insulin pumps are electronic
devices that are worn continuously
and deliver insulin into the fat layer
below the skin by way of a fl exible
plastic tube (similar to the “port”
described above). Insulin pumps are
popular among those who require
multiple daily injections of insulin.
Safe and successful use of a pump
requires considerable education
and training, and their cost can be
relatively high. Insulin pumps are
not typically used by those who are
new to insulin, but can be an eff ec-
tive option once you have a bit
more experience.
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INSULIN INJECTION
KNOW-HOW
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INSULIN INJECTION
KNOW-HOW
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Supported by BD Diabetes Care
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American Association of Diabetes Educators
insulin injection
know-how
learning how to
inject insulin
3
Choosing an injeCtion
deviCe
The decision to use syringes or
pens is a personal one. If you have
an opportunity to sample both at
your healthcare provider’s office,
certainly do so. It is best to speak
with your healthcare provider and
check with your health insurance
to find out what is covered under
your plan.
Most pens hold 300 units of insulin
and allow delivery of up to 60 to 80
units at a time. “Prefilled” dispos-
able pens deliver in single-unit
increments. “Durable” pens utilize
replaceable/ insulin cartridges, and
may deliver insulin in 1/2 unit incre-
ments. Pens can be used to deliver
a variety of long-acting and rapid-
acting insulin types, as well as
premixed insulin formulations.
Disposable syringes hold up to 100
units per injection. If you decide to
use syringes, select a type that
holds enough to cover your largest
dose with a little room to spare. The
markings on a syringe allow dosing
in 2-unit, 1-unit, or 1/2-unit incre-
ments. Once you have a size that
meets your needs, select a type
that allows you to dose as precisely
as possible.
The needles on syringes vary as
well. Syringe and pen needles as
short as 4mm and as long as 12.7mm
are available. Thickness is measured
in gauge. The higher the gauge, the
thinner the needle. Gauges as high
as 32 and as low as 28-gauge can
be obtained. In general, it is best to
use the shortest, thinnest (highest
gauge) needles available. Skin
thickness doesn’t vary much from
person to person. Even if you are
overweight or obese, it is unlikely
that you will need a needle longer
than 6mm. Needles that are too
long may produce painful intra-
muscular injections, with insulin
absorbing faster than it should.
Supported by BD Diabetes Care
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American Association of Diabetes Educators
insulin injection
know-how
learning how to
inject insulin
4
to dRaW one tYPe oF insULin
into a sYRinge:
Ã
gather your insulin supplies:
Get your insulin vial and a fresh
syringe. Check the insulin vial to
make sure it is the right kind of
insulin and that there are no
clumps or particles in it. Also
make sure the insulin is not
being used past its expiration
date.
Ã
gently stir intermediate or
premixed insulin: Turn the
bottle on its side and roll it
between the palms of your
hands. Clear (fast-acting, long-
acting) insulin generally does
not need to be mixed.
Ã
Prepare the insulin bottle: If
the insulin bottle is new, remove
the cap. It is not necessary to
wipe the top of the bottle with
alcohol as long as it is clean.
Ã
Pull air into the syringe:
Remove the cap from the
needle. Pull back the plunger
on the syringe to draw in an
amount of air that is equal to
your insulin dose. The TIP of
the black plunger should
correspond to the number
on the syringe.
Ã
inject air into the vial: Hold
the syringe like a pencil and
insert the needle into the
rubber stopper on the top of
the vial. Push the plunger down
until all of the air is in the bottle.
This helps to keep the right
amount of pressure in the bottle
and makes it easier to draw up
the insulin.
Ã
draw up the insulin into the
syringe: With the needle still
in the vial, turn the bottle and
syringe upside down (vial above
syringe). Pull the plunger to fi ll
the syringe to the desired
amount.
Ã
Check the syringe for air
bubbles: If you see any large
bubbles, push the plunger until
the air is purged out of the
syringe. Pull the plunger back
down to the desired dose.
Ã
Remove the needle from the
bottle: Be careful to not let the
needle touch anything until you
are ready to inject!
INJECTION TECHNIQUE
Technique is everything when it comes to
making insulin injections easy.
INSULIN INJECTION
KNOW-HOW
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American Association of Diabetes Educators
insulin injection
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learning how to
inject insulin
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When CoMBining tWo tYPes
oF insULin (inteRMediate
and RaPid) in the saMe
sYRinge:
Ã
gather your insulin supplies:
Get your insulin vial and a fresh
syringe. Check the insulin vial to
make sure it is the right kind of
insulin and that there are no
clumps or particles in it, and
that the expiration date has not
passed.
Ã
gently stir intermediate or
premixed insulin: Turn the vial
on its side and roll it between
the palms of your hands. Clear
(fast-acting, long-acting) insulin
generally does not need to be
mixed.
Ã
Prepare the insulin vials: If the
insulin vial is new, remove the
cap. It is not necessary to wipe
the top of the bottle with
alcohol as long as it is clean.
Ã
inject air into the intermedi-
ate insulin vial: Remove the
cap from the needle. With the
vial of insulin below the syringe,
inject an amount of air equal to
the dose of intermediate insulin
that you will be taking. Do not
draw out the insulin into the
syringe yet. Remove the needle
from the vial.
Ã
inject air into the rapid-
acting insulin vial: Only inject
an amount equal to the rapid-
acting insulin dose. Leave the
needle in the vial.
Ã
draw up the rapid-acting
insulin: With the needle still in
the vial, turn the vial upside
down (vial above the syringe)
and pull the plunger to fi ll the
syringe with the desired dose.
Ã
Check the syringe for air
bubbles: If you see any large
bubbles, push the plunger until
the air is purged out of the
syringe. Pull the plunger back
down to the desired dose.
Ã
Remove the needle from the
vial: Recheck your dose.
Ã
draw up the intermediate-
acting insulin: Insert the
needle into the vial of cloudy
insulin. Turn the vial upside
down (vial above syringe) and
pull the plunger to draw the
dose of intermediate-acting
INSULIN INJECTION
KNOW-HOW
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American Association of Diabetes Educators
insulin injection
know-how
learning how to
inject insulin
6
insulin. Because the short-
acting insulin is already in the
syringe, pull the plunger to the
total number of units you need.
Do not inject any of the insulin
back into the vial, since the
syringe now contains a mixture
of intermediate and rapid-
acting insulin.
Ã
Remove the needle from the
vial: Be careful to not let the
needle touch anything until you
are ready to inject!
PRePaRing a Pen FoR
injeCtion:
Ã
Check the pen: Ensure that it
contains the proper type of
insulin and contains enough to
cover your full dose. Also check
to make sure that the expiration
date has not passed.
Ã
gently stir intermediate or
premixed insulin: Turn the
pen on its side and roll it
between the palms of your
hands. Clear (fast-acting,
long-acting) insulin generally
does not need to be mixed.
Ã
attach a fresh pen needle:
Screw or click the needle
securely in place according to
the manufacturer’s instructions.
Remove the cap(s) from the pen
needle to expose the needle.
Ã
Prime the pen: Pointing the
needle up in the air, dial one
or two units on the pen and
press the plunger fully with
your thumb. Repeat until a
drop appears.
Ã
dial your dose: Turn the dial
on the pen to your prescribed
dose.
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American Association of Diabetes Educators
insulin injection
know-how
learning how to
inject insulin
7
deLiveRing an injeCtion:
Ã
select a site: Choose a spot on
your skin that you can see and
reach. It is important to not
“overuse” any particular area of
skin. See the information below
on “rotating” injection sites.
Ã
Make sure skin is clean: It is
generally not necessary to wipe
the skin with alcohol before
injecting. Those at a high risk of
infection should discuss site-
preparation procedures with
their healthcare team.
Ã
Pinch the skin: Pinch a one-to-
two-inch portion of skin and fat
between your thumb and fi rst
fi nger.
Ã
Push the needle into the skin:
With your other hand, hold the
syringe or pen like a pencil at a
90-degree angle to the skin and
insert the needle with one quick
motion. Make sure the needle is
all the way in.
Ã
inject the insulin: Let go of the
skin pinch before you inject the
insulin. Push the plunger with
your thumb at a moderate,
steady pace until the insulin is
fully injected. If using a syringe,
keep the needle in the skin
for 5 seconds. If using a pen,
keep the needle in the skin
for 10 seconds.
Ã
Pull out the needle: Remove at
the same 90-degree angle at
which you inserted the needle.
Press your injection site with
your fi nger for 5-10 seconds to
keep insulin from leaking out.
Ã
Remove the needle: If using a
pen, remove the needle from
the pen by replacing the large
cover and unscrewing. Leaving
the needle on the pen can
result in leakage or air bubbles.
Ã
dispose of your used needle: It
is important to protect yourself,
your loved ones, sanitation
workers and pets from acciden-
tal needle sticks. Do not recap
syringes before throwing them
away. Place used syringes and
pen needles in a thick plastic
container (sharps container,
detergent bottle, etc.). When
nearly full, close the container
tightly with a screw-on cap and
tape closed. Dispose according
to standards set forth by your
local department of sanitation.
ABDOMEN
THIGHS
BUTTOCKS
ARMS
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ABDOMEN
THIGHS
BUTTOCKS
ARMS
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Correct (left ) and incorrect (right) ways of performing the skin fold.
the correct angle of injection
when lift ing a skin fold is 90°
Supported by BD Diabetes Care
8
American Association of Diabetes Educators
insulin injection
know-how
learning how to
inject insulin
8
ROTATING INJECTION
SITES:
Insulin is injected into the fat layer
below the skin on the abdomen
(staying two fi ngers or a few inches
away from the belly button), outer
thighs, hips, buttocks, or backs of
the arms. Although insulin injec-
tions are usually painless, injecting
the same spot repeatedly can cause
infl ammation or fat tissue break-
down. Lipodystrophy, as this is
called, can cause lumps/swelling
and thickened skin, and it may keep
insulin from absorbing properly.
Nearly half of all people who take
insulin develop lipodystrophy,
particularly when injection sites are
not rotated properly.
Most forms of rapid and long-acting
insulin absorb consistently from just
about any body part, so feel free to
use a variety of body parts for your
injections, and use a variety of
spots within each body part.
Intermediate-acting (cloudy)
insulin and premixed insulin absorbs
diff erently in diff erent body parts. It
is best to inject intermediate-acting
insulin into one part of the body
consistently, but use a variety of
spots within that body part.
needLe Re-Use
Use of a new, fresh syringe or pen
needle for each injection is the best
way to minimize discomfort and
ensure the accuracy/eff ectiveness
of the insulin dose. Using someone
else’s needle puts you at danger of
contracting Hepatitis and HIV.
ABDOMEN
THIGHS
BUTTOCKS
ARMS
1
6
11
2
7
12
3
8
13
4
9
14
5
10
15
5
6
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4
7
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8
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2
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ABDOMEN
THIGHS
BUTTOCKS
ARMS
1
6
11
2
7
12
3
8
13
4
9
14
5
10
15
5
6
15
4
7
14
3
8
13
2
9
12
1
10
11
ABDOMEN
THIGHS
BUTTOCKS
ARMS
1
6
11
2
7
12
3
8
13
4
9
14
5
10
15
5
6
15
4
7
14
3
8
13
2
9
12
1
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Recommended way to rotate
injection sites.
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