Columbia University Medical Center
2007-2010 Fellow, Gastroenterology
New York Presbyterian Hospital
Weill-Cornell Medical Center
AMERICAN BOARD OF INTERNAL MEDICINE CERTIFICATION Internal Medicine, 2006
Gastroenterology and Hepatology, 2010
Transplant Hepatology, 2012
LICENSURE New York State Medical License #237817
HONORS/AWARDS EASL Clinical School of Hepatology Attendee, Hannover, Germany 2009
EASL Young Investigatory Travel Bursary 2009
Fellowship to Leadership Gastroenterology/Hepatology Travel Grant 2009
New York Presbyterian House Staff Teaching Award 2008
American Liver Foundation AASLD Resident Scholar Award 2005
Arnold P. Gold Foundation Humanism in Medicine Award 2003
Alpha Omega Alpha (AOA) Medical Honor Society 2002
NJMS Deans Letter of Commendation 2001
NJMS Pre-Clinical Letter of Commendation 2000
McGill University Teaching Assistant of Excellence Award 1998, 1999
OTHER PROFESSIONAL ROLES 2016 – present Program Director, Gastroenterology Fellowship
Mount Sinai Beth Israel Medical Center
2010 – 2015 Director of Hepatology, Lenox Hill Hospital
2010 – 2015 Core Clinical Faculty, Department of Gastroenterology and Hepatology
Lenox Hill Hospital
RESEARCH PROFILE My research has focused on viral hepatitis and the complications of cirrhosis, specifically management of portal hypertension and cardiac evaluation of patients awaiting liver transplantation. Most of my research was conducted under the guidance of Dr. Samuel Sigal. Investigator initiated research assessed the role of small intestinal bacterial overgrowth in hepatic encephalopathy, the impact of depression and fatigue in cirrhosis, and the optimal strategy for albumin utilization in bacterial peritonitis. In addition, industry supported research has included terlipressin for type II hepatorenal syndrome, vapreotide for the prevention of recurrent esophageal variceal hemorrhage, and rifaximin for the prevention of recurrent hepatic encephalopathy. Research has been presented at national and international society meetings.
CLINICAL PROFILE My clinical practice focuses on the care and management of patients living with chronic liver disease, including endoscopic procedures for management of portal hypertension. I have a particular interest in chronic viral hepatitis, hepatocellular carcinoma, and prevention and management of the complications of portal hypertension. In addition, my practice includes evaluation of patients for orthotopic liver transplantation and optimization and management of patients before and after transplant surgery.
My research has been presented at both national and international liver society meetings. Industry sponsored research was published in major peer reviewed journals and became part of the standard of care for the management of hepatic encephalopathy and hepatorenal syndrome. The hepatology teaching program that I run plays an instrumental role in the education of fellows at Lenox Hill Hospital.
Program Director for Mount Sinai Beth Israel Gastroenterology and Hepatolgy Fellowship
6 Gastroenterology Fellows
8- 10 hours per week
2016 - present
PUBLICATIONS Peer Reviewed Articles Goldberg D, Weisberg I, Diuguid D, Gaglio P, Alobeid D, Fink S, Radhakrishan J. Worth a second look. Am J Med. 2009; 122(1): 24-26.
Weisberg IS, Park E, Nunn M, Berger P, Suh D, Breksa AP III, Garrow TA, Rozen R. Investigations of a common genetic variant in betaine-homocysteine methyltransferase (BHMT) in coronary artery disease. Atherosclerosis. 2003; 167(2): 205-214.
Morin I, Platt R, Weisberg IS, Sabbaghian N, Wu Q, Garrow TA, Rozen R. A common variant in betaine-homocysteine methyltransferase (BHMT) and risk for spina bifida. Amer J Med Genet. 2003; 119(2): 172-6.
Sibani S, Leclerc D, Weisberg IS, O’Ferrall E, Watkins D, Artigas C, Rosenblatt DS, Rozen R. Characterization of mutations in severe methylenetettrahydrofolate Reductase (MTHFR) deficiency reveals an FAD responsive mutation. Hum Mut 2003; 21(5) 509-520.
Weisberg IS, Jacques PF, Selhub J, Bostom AG, Chen Z, Curtis Ellison R, Eckfeldt JH, Rozen R. The 1298AC polymorphism in methylenetetra-hydrofolate Reductase (MTHFR): in vitro expression and association with homocysteine. Atherosclerosis 2001; 156(2): 409-415.
Sibani S, Leclerc D, Weisberg I, Rozen R. The silent T1317C mutation of methylene-tetrahydrofolate reductase (MTHFR) should not interfere with MboII restriction isotyping of the reported 1298AC mutation. Mol Genet Metab. Letter. 1999; 68(4): 512.
Weisberg I, Tran P, Christensen B, Sibani S, Rozen R. A second genetic polymorphism in methylenetetrahydrofolate reductase (MTHFR) associated with decreased enzyme activity. Mol Genet Metab 1998; 64(3): 169-172.
Invited Contributions Weisberg IS and Jacobson IM. Cardiovascular disease and the liver. Clinics in Liver Disease. 2011; 15(1): 1-20.
Weisberg IS and Jacobson IM. Telaprevir: Hope on the Horizon, Getting Closer. Clinics in Liver Disease. 2009; 13(3): 441-452
Weisberg IS, Brown RS, Jr., Sigal SH. Hepatitis B and end-stage liver disease. Clin Liv Dis 2007; 11(4): 893-916.
Weisberg IS, Brown RS, Jr. Current and future trends in liver replacement therapy. US Gastroenterol Rev. 2007.
Abstracts and Presentations
Weisberg IS, Mehta M, Nazareth, S, Razavi F, Brown RS, Jr. Pretransplant cardiac risk stratification before orthotopic liver transplantation: Apprasial of the AHA/ACC guidelines for high-risk noncardiac surgery. Plenary. American Association for the Study of Liver Diseases, 2010, Boston, MA, USA.
Weisberg IS, Mehta M, Nazareth, S, Razavi F, Brown RS, Jr. Risk factors for cardiac events and early mortality after orthotopic liver transplantation: The New York Presbyterian Hospital experience. Abstract. American Association for the Study of Liver Diseases, 2010, Boston, MA, USA.
Weisberg IS, Sharaiha R, Goldberg D, Ascunce G, Sigal SH. A kidney function determined treatment algorithm for albumin administration in the management of spontaneous bacterial peritonitis (SBP). Abstract. Digestive Disease Week (DDW) 2009, Chicago, IL, USA.
Weisberg IS, Jesudian AB, Barboza KC, Liu T, Bosworth BP, Sigal SH. The role of small intestinal bacterial overgrowth (SIBO) in hepatic encephalopathy. Abstract. Digestive Disease Week (DDW) 2009, Chicago, IL, USA.
Weisberg IS, Jesudian AB, Barboza KC, Liu T, Bosworth BP, Sigal SH. The role of small intestinal bacterial overgrowth (SIBO) in hepatic encephalopathy. Abstract. European Association for the Study of Liver Disease (EASL) 2009, Copenhagen Denmark.
Weisberg IS, Cavell L, Weine D, Scherl E. Bleeding duodenal diverticulum – Hemostasis after endoscopic hemoclip placement. Abstract. American College of Gastroenterolgy 2008. Orlando USA.
Weine DM, Kulkarni K, Weisberg IS, Schaefer R, Jajoo K, Frissora C. The cola wars continue: use of diet Pepsi for Bezoar dissolution. Abstract. American College of Gastroenterology 2008. Orlando USA.
Al Sibae M, Weisberg IS, Talal A, Jacobson IM. Frequency and significance of anti-actin antibodies in HIV/HCV coinfected patients. Abstract. American Association for the Study of Liver Disease 2007. Boston USA.
Novogrudsky A, Weisberg IS, Abrhams J, Green P. Disappointing sensitivity and specificity of the TTG antibody in celiac disease. 69th American Gastroenterology Meeting. Tampa, Florida, 2003.
Burkland, D, Goebel M, Weisberg IS, Holland B, Oleske JM. Effectiveness of a medical student preventative health program for HIV in middle school children. Abstract. International AIDS Conference. Durban, South Africa, 2000.
Weisberg IS, Jacques PF, Selhub J, Bostom AG, Chen Z, Curtis Ellison R, Eckfeldt JH, Rozen R. The 1298AC polymorphism in methylenetetrahydrofolate reductase (MTHFR): in vitro expression and association with homocysteine. Abstract. Pediatric Societies and the American Academy of Pediatrics Year 2000 Joint Meeting. Boston, USA.
Book Chapters Weisberg IS, Sigal SH, Brown RS, Jr. Transvenous liver biopsy. Clinical Hepatology – Principles and Practice of Hepatobiliary Disease. Springer. 2009.
Weisberg IS, Jacobson IM. The inactive carrier state: Management of the HBeAg negative chronic HBV patient with minimal viremia and normal liver enzymes. Clinical Dilemmas in Viral Liver Disease. 2010.
INVITED LECTURES/PRESENTATIONS Gastroenterology Grand Rounds Yale University Medical Center
May 2010 Liver Transplant for Alcoholic Hepatitis
Internal Medicine Grand Rounds Memorial Sloan Kettering Cancer Center
September 2011 Hepatitis C: Current and Future Trends Gastroenterology Grand Rounds Lenox Hill Hospital
July 2013 Hepatitis C: Current and Future Trends Empire Liver Foundation Shifting Paradigm in Management of HCV