(844.9)
43. THE PROMISES AND PITFALLS OF RESEARCH
USING DIETARY PATTERNS
Symposium
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orDas
3:00 Overview.
L. M. Troy. Univ. of Massachusetts Amherst.
3:05
An overview and framework for dietary patterns
research.
J. Reedy. NCI, NIH.
3:30
Applying classification and regression tree analysis to
expand dietary patterns research.
P. Miller. Exponent
Inc.
3:55 Temporal dietary patterns and other contextual
information to expand dietary patterns research.
H. A.
Eicher-Miller. Purdue Univ.
4:20
A candid overview of the pitfalls to stimulate the next
generation of dietary pattern methodology.
C. J.
Boushey. Univ. of Hawaii Cancer Ctr.
4:45 Discussion.
S. Krebs-Smith. NCI, NIH.
44. THE WHO EVIDENCE-INFORMED GUIDELINE
DEVELOPMENT PROCESS: IMPLICATIONS
FOR VITAMIN AND MINERAL RESEARCH
PRIORITIES
Symposium
(Supported by an educational grant from the World
Health Organization)
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Global and Public Health Nutrition
3:00 Introduction.
L. Neufeld. Micronutrient Initiative, Ottawa.
3:15 WHO’s evidence-informed guideline development
process.
J. P. Pena-Rosas. WHO.
3:30
Evidence in guideline development: from RCTs to
observational studies to program reports.
D. Tovey.
Cochrane Library of Evidence.
3:45
Negotiating policy change based on WHO guidelines.
C.
Lutter. Pan American Hlth. Org.
4:00 How can the scientific community support the
generation of the evidence needed to improve the
quality of guidelines for micronutrient interventions?
R. J. Stoltzfus. Cornell Univ.
SATURDAY NUTRITION
12
4:15
Promoting dialogue among the research and policy
program communities.
J-P. Habicht. Cornell Univ.
4:30 Discussion.
45. BIOACTIVE COMPOUNDS AND OTHER MILK
CONSTITUENTS
Minisymposium
(Sponsored by: Lactation RIS)
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onneCKe
3:00
45.1
Human and bovine osteopontin from milk
and recombinant human osteopontin may stimulate intestinal
proliferation and immune functions via various mechanisms
revealed by microarray analysis.
R. Jiang and B. Lonnerdal.
Univ. of California, Davis.
3:15
45.2
Arachidonic acid and docosahexaenoic acid
attenuate inflammation in human fetal but not adult intestinal
epithelial cells.
V. Wijendran, W. Zhu, J.T. Brenna, S.M. Innis
and W.A. Walker. Massachusetts Gen. Hosp., Charlestown,
Cornell Univ. and Univ. of British Columbia.
3:30
45.3
Lactoferrin modulates microbe-associated
molecular pattern- and cytokine-induced inflammation in
human fetal intestinal epithelial cells.
E.B. Nonnecke, S.G.
Winters and B.L. Lönnerdal. Univ. of California, Davis.
3:45
45.4
Principal human milk oligosaccharides utilized
by human gut microbiota.
Z-T. Yu, B. Liu and D.S. Newburg.
Boston Col.
4:00
45.5
Relationship between human milk
oligosaccharides and fecal microbiome of breastfed infants.
J.E. Williams, M.A. Riley, S.L. Brooker, K.M. Hunt, A.
Szyszka, L. Bode, M.K. McGuire and M.A. McGuire. Univ. of
Idaho, Washington State Univ. and UCSD.
4:15
45.6
Human milk oligosaccharides reduce EPEC
attachment in vitro and EPEC colonization in mice.
C.F.
Manthey, C. Autran, L. Eckmann and L. Bode. UCSD, La
Jolla and San Diego.
4:30
45.7
Milk 3’ sialyllactose does not increase brain
sialic acid concentration in mice.
C. Autran, A. Szyszka and L.
Bode. UCSD.
4:45
45.8
Detection of the endocannabinoid metabolome
in human plasma and breast milk.
H.A. Durham, J.T. Wood,
S.K. Vadivel, A. Makriyannis and C.J. Lammi-Keefe.
Pennington Biomed. Res. Ctr., Baton Rouge, Northeastern
Univ., LSU and LSU AgCtr.
46. NUTRITION AND INFLAMMATION
Minisymposium
(Sponsored by: Medical Nutrition Council)
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3:00
46.1
Lipoprotein lipase affects macrophage content
and phenotype in aorta and adipose tissue.
C.L. Chang, I.
Garcia-Arco, J.Y. Kim, I.J. Goldberg and R.J. Deckelbaum.
Columbia Univ.
3:15
46.2
Substituting dietary monounsaturated fat for
saturated fat lowers inflammasome activation observed on a
high saturated fat diet.
C.L. Kien, K.I. Crain, J.Y. Bunn, N.K.
Fukagawa and M.E. Poynter. Univ. of Vermont, Colchester
and Burlington.
3:30
46.3
Effects of high-dose cholecalciferol on serum
markers of inflammation and immunity in patients with early
chronic kidney disease.
J.A. Alvarez, S.M. Zughaier, J. Law,
L. Hao, H. Wasse, T.R. Ziegler and V. Tangpricha. Emory Univ.
Sch. of Med., Emory+Children’s Ctr. for Cystic Fibrosis Res.
and Atlanta VA Med. Ctr.
3:45
46.4
Loss of tumor necrosis factor-alpha diminishes
indicators of colonic Wnt-signaling activation induced by
obesity.
Z. Liu, S. Kim, A.C. Pfalzer and J.B. Mason. Sch. of
Publ. Hlth. and Hlth. Sci., Univ. of Massachusetts Amherst and
USDA at Tufts Univ.
4:00
46.5
Cholesterol-induced inflammation on adipose
tissue is reduced by a carbohydrate restricted diet in guinea
pigs.
D. Aguilar, R. deOgburn, J.S. Volek and M.L. Fernandez.
Univ. of Connecticut.
4:15
46.6
Effects of leucine and adipocyte derived
microparticles on human peripheral blood monocyte CD11b
expression.
B. Curry, J. Biggerstaff and M.B. Zemel. Univ. of
Tennessee, Knoxville.
4:30
46.7
Activation of RelA (p65), but not of p50 dimers
of nuclear factor kappa B is decreased in impaired renal
function.
G. Faustmann, J.M. Roob, H-J. Gruber, H. Hafner-
Giessauf, J. Grabher, B. Tiran and B.M. Winklhofer-Roob.
Karl-Franzens Univ. and Med. Univ., Graz, Austria.
4:45
46.8
Leucine and calcitriol modulation of human
airway inflammation in lung endothelial cells.
P. Brown, M.
Johnstone and M.B. Zemel. Univ. of Tennessee, Knoxville.
47. EDUCATION AND TEACHING
Minisymposium
(Sponsored by: Medical Nutrition Council)
(Cosponsored by: Nutrition Education in Professional
Schools Subcommittee)
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3:00
47.1
Future directions for implementing nutrition
across the continuum of medical and health professions
education and training, and research.
P.M. Kris-Etherton, S.
Akabas, C. Pratt, E. Saltzman, N. Krebs and M. Levy. Penn
State, Columbia Univ., NHLBI, NIH, Tufts Univ. Sch. of Med.,
Univ. of Colorado, Aurora and Medstar Georgetown Univ. Hosp.
3:15
47.2
Need for nutrition education programme: laying
the foundations of nutrition knowledge relevant to clinical and
public health practice.
S. Ray, C. Laur and NNEdPro Group.
Need for Nutr. Educ. Prog., Cambridge, U.K.
3:30
47.3
A multidisciplinary and formal nutrition
education is needed in graduate medical education.
B.J. Daley,
S. McClave, C. Van Way, L. Gramlich, J. Cherry-Bukoweic,
B. Collier and C. Lawson. Univ. of Tennessee Med. Ctr.,
Knoxville, Univ. of Louisville, Univ. of Missouri-Kansas City,
Univ. of Alberta, Univ. of Michigan and Carillon Clin., Roanoke,
VA.
NUTRITION SATURDAY
13
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3:45
47.4
Using the “Rate Your Plate” questionnaire
to teach nutrition changed medical student eating habits.
E.
Vargas Valls, G. Gadey and R. Zelis. Penn State Hershey
Heart and Vasc. Inst.
4:00
47.5
Nutrition and health elective for first year
medical students.
Y. Mossavar-Rahmani, M. Reznik, J.
Barnhart, N. Davis, B. Kligler and W. Burton. Albert Einstein
Col. of Med. and Montefiore Med. Ctr., Bronx.
4:15
47.6
Just what the doctor ordered: novel medical
student nutritional education through community-based
cooking classes.
A.G. Birkhead, J. Loyd, B. Leong, E. Joo, D.
Monlezun, D. Kay, L. Abu-Shamat, L. Sarris and T. Harlan.
Tulane Univ.
4:30
47.7
Nutrition in medicine: effectiveness of a web-
based curriculum for obstetrics and gynecology residents.
B.
Suskin Kaplan, C.E. Karkowsky, M. Kohlmeier, A. Dayal, C.
Chazotte and E. Landsberger. Albert Einstein Col. of Med.,
Montefiore Med. Ctr., Bronx and Univ. of North Carolina at
Chapel Hill Schs. of Med. and Publ. Hlth.
4:45
47.8
Innovative postdoctoral fellowship in medical
nutrition.
S.E. Ettinger, J. Nasser, E. Engelson, J. Albu, S.
Hashim and F.X. Pi-Sunyer. St. Lukes Roosevelt Hosp. Ctr.,
NY and Drexel Univ.
48. OBESITY AND THE METABOLIC SYNDROME I
Minisymposium
(Sponsored by: Energy and Macronutrient Metabolism RIS)
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C
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: e. e
van
3:00
48.1
Relationship between hepatic steatosis
progression and cardiovascular performance under chronic
nutritional overload.
A.F. Nascimento, R.A.M. Luvizotto, A.O.
Martins, T.A.S. Oliveira, X-D. Wang and A.C. Cicogna. São
Paulo State Univ., Botucatu and USDA at Tufts Univ.
3:15
48.2
Natural infection of human adenovirus 36 in
rhesus monkeys is associated with gain in body fat, yet, reduction
in fasting glucose.
N.V. Dhurandhar, E.J. Dhurandhar, D.K.
Ingram, R. de Cabo and J.A. Mattison. Pennington Biomed.
Res. Ctr., Baton Rouge, Univ. of Alabama at Birmingham and
NIA, NIH, Baltimore.
3:30
48.3
Dietary linoleic acid elevates endogenous
endocannabinoids (2-AG and anandamide) and induces
obesity.
J.R. Hibbeln, M. Malde, D. Osei-Hyiaman, Y.H. Lin,
R. Pawlosky, L. Madsen, K. Kristiansen, L. Frøyland and
A. Avelheim. NIAAA, NIH, Rockville, Natl. Inst. of Nutr. and
Seafood Res., Bergen, Norway, Nippon Boehringer Ingelheim
Co. Ltd., Kobe, Japan and Univ. of Copenhagen.
3:45
48.4
Dietary macronutrients modulate the fatty
acyl composition of rat liver mitochondrial cardiolipins.
I.G.
Stavrovskaya, S.S. Bird, V.R. Marur, M.J. Sniatynski, S.V.
Baranov, H.K. Greenberg, C.L. Porter and B.S. Kristal.
Brigham and Women’s Hosp., Harvard Med. Sch. and Univ. of
Pittsburgh Med. Ctr.
4:00
48.5
Autologous subcutaneous adipose tissue
transplant in diet-induced obese rats.
G.M. Torres-Villalobos,
N. Hamdan-Pérez, N. Torres, G. Ordaz-Nava, S. Moran-
Ramos, L. Noriega, C. Bravo-Reyna, I. Torre-Villalvazo, M.
Hiriart and R. Medina-Santillan. Salvador Zubiran Natl. Inst.
of Med. Sci. and Nutr., Mexico City.
4:15
48.6
Impact of caspase-11 non-canonical
inflammasome on adipose tissue inflammation and obesity-
induced insulin resistance.
R.W. Grant, Y-H. Youm, D. Albarado
and V.D. Dixit. Pennington Biomed. Res. Ctr., Baton Rouge.
4:30
48.7
Using a diet and drug combination treatment
prior to pregnancy to improve maternal health in rats.
R.A.
Reimer and A.J. Eslinger. Univ. of Calgary, Canada.
4:45
48.8
1,25(OH)2D3 decreases leptin, IL-6 and SAA
expression in human adipocytes: role of vitamin D receptor.
M. Lee, H. Nimitphong, W. Guo, M.F. Holick and S.K. Fried.
Boston Univ. and Ramathibodi Hosp. , Bangkok.
SATURDAY NUTRITION
14
Pathology
52. BIOINFORMATICS, BIOBANKING AND IMAGING
TECHNIQUES
Minisymposium
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: p. B
autista
Biomarkers and Biobanking
8:30
52.1
Pulmonary hypertension associated with
human immunodeficiency virus: uncovering viral evolution via
bioinformatics.
R.A. López-Astacio, S.M. Reno, R.O. Schoen,
S. Castro-Flores and S. Almodóvar. Univ. of Puerto Rico at
Ponce and Univ. of Colorado Denver, Aurora.
8:50
52.2
Bioinformatics analysis of Mycobacterium
tuberculosis-specific genomic regions to identify
immunodominant proteins and peptides.
AS. Mustafa. Fac. of
Med., Kuwait Univ.
9:10
52.3
Systematic analysis of the gene expression
in the livers of nonalcoholic steatohepatitis: implications on
potential biomarkers and molecular pathological mechanism.
Y. Zhang, S.S. Baker, R.D. Baker, R. Zhu and L. Zhu. Tongji
Univ., China and SUNY at Buffalo.
9:30
52.4
Development of a viewing system for a whole
tissue from multiple tissue blocks.
N. Hashimoto, T. Tanaka,
M. Snuderl and Y. Yagi. Massachusetts Gen. Hosp., Harvard
Med. Sch. and Chiba Univ.
9:50
52.5
3D-based approach for efficient analysis of
immunostained histology images in evaluating downstream
pathway activation in malignant tumors with molecular targets.
Y. Yagi, P.A. Bautista, V. Klepeis and M. Mino-Kenudson.
Massachusetts Gen. Hosp.
10:10
52.6
Improved color visualization of histological
structures through multispectral image fusion.
P.A. Bautista
and Y. Yagi. Massachusetts Gen. Hosp.
10:30
52.7
Imaging interactions between transferrin-
containing endosomes and mitochondria.
A. Das, S. Nag and
M. Barroso. Albany Med. Ctr.
10:50
52.8
The impact of different additives to neutral
buffered formalin.
S.M. Hewitt, C.D. Perry, K. Ylaya, J. Morris
and J-Y. Chung. NCI, NIH.
11:10
Low voltage transmission electron microscopy
in cell biology.
M. Bendayan. Univ. of Montreal. (874.28)
49. PATHOBIOLOGY FOR BASIC SCIENTISTS:
NEOPLASIA: FUNDAMENTAL THEMES IN
NEOPLASIA — WHEN GOOD CELLS GO BAD
Course
(Supported by an educational grant from Academic
Press)
(Sponsored by: ASIP Education Committee)
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G.J. t
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Education
Neoplasia
8:30
Basic concepts in cancer pathobiology and Introduction
to molecular carcinogenesis.
W. B. Coleman. Univ. of
North Carolina at Chapel Hill Sch. of Med.
10:00 Molecular diagnostics in human cancer.
G. Tsongalis.
Dartmouth-Hitchcock Med. Ctr., Geisel Sch. of Med.
at Dartmouth.
50. MOLECULAR AND CELLULAR BASIS OF
DISEASE: MOLECULAR BIOLOGY OF
INFLAMMATION AND NON-TLR PATTERN
RECOGNITION RECEPTORS
Symposium
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t. K
yriaKiDes
Inflammation
8:30
Role of NLRs in innate immunity and inflammatory
diseases.
T. Kanneganti. St. Jude Children’s Res.
Hosp.
9:20
Damage molecules: agonists and biomarkers in sepsis
and SIRS.
C. Hauser. Harvard Med. Sch.
10:10 Cell biological aspects of innate immunity.
J. Kagan.
Harvard Med. Sch.
11:00 Break.
2:00
Role of NLRs and the microbiota in eradication of enteric
pathogens.
G. Nunez. Univ. of Michigan.
2:50
Regulation of inflammasome activation.
W. Mehal. Yale
Sch. of Med.
3:40
Macrophage phenotype modulation in atherosclerosis.
K. Ley. La Jolla Inst. for Allergy & Immunol.
PATHOLOGY SATURDAY
15
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53. STEM CELL BIOLOGY AND MOLECULAR
PROFILING IN MALIGNANCIES
Minisymposium
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arroll
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taChler
Stem Cells
8:30
53.1
SIRT2 overexpression in hepatocellular
carcinoma mediates epithelial to mesenchymal transition via
Akt/GSK-3
b/b-catenin signaling. B.C-B. Ko, J. Chen, A. Chen,
P.B.S. Lai and A. Huang. The Chinese Univ. of Hong Kong and
Chongqing Med. Univ., China.
8:50
53.2
Broad genotyping of consecutive endometrial
cancer samples enables the identification of rare and novel
mutations.
M.D. Stachler and N. Lindeman. Brigham and
Women’s Hosp.
9:10
53.3
Profiling miRNAs in renal neoplasms for
diagnosis and biomarker discovery.
S. Sam, A.R. Schned, G.J.
Tsongalis and L.J. Tafe. Dartmouth-Hitchcock Med. Ctr.
9:30
53.4
Spontaneous salivary gland carcinomas in
GON4l deficient mice.
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