1 friday, april 19 Biochemistry and Molecular Biology asbmb graduate and postdoctoral travel award keynote lecture special Session
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Panelists: T. A. Baker, MIT, D. Cavalier, Science Cheerleader, C. Mello, HHMI/Univ. of Massachusetts Med. Sch. 94. WILLIAM C. ROSE AWARD LECTURE Award s un . 2:55 pm —B oston C onvention & e xhiBition C enter
, 258a 2:55
Introductory remarks. J. D. Scott. 3:00
94.1 Decoding ubiquitin networks in regulation of inflammation and autophagy.
s un . 3:45 pm —B oston C onvention & e xhiBition C enter
, 252aB C haired : s. B ell
3:45
Chair’s introduction. 3:50 95.1 Pif1 helicases: helping replication forks maneuver past replication barriers.
4:15 Interplay of DNA polymerase lambda, protection of telomeres 1 and TERRA in telomere elongation.
Fed. Polytech. Sch. of Lausanne and Univ. of Zürich-Irchel. (538.4) 4:30
95.2 Chromatin replication and epigenome maintenance.
4:55
Coordinated degradation of replisome components ensures genome stability upon replication stress. E. Noguchi, L. Roseaurlin and T. Toda. Drexel Univ. Col. of Med. and Cancer Res. UK, London. (968.4) 5:10
Probing the nucleic acid binding modes of the single-stranded DNA binding protein of the bacteriophage T4 replication complex.
5:25
95.3 Mechanism of replication-coupled DNA interstrand cross-link repair.
5:50
Discussion and closing remarks. 96. HOW RNA MOLECULES BEHAVE AND MISBEHAVE Symposium s un . 3:45 pm —B oston C onvention & e xhiBition C enter
, 253a C haired : D. h ersChlaG
3:45
Chair’s introduction. 3:50 96.1 Predictive understanding of RNA dynamic behavior: bringing order to disorder.
Michigan. 4:15 Comprehensive mechanistic analysis of the RNA-lariat debranching enzyme. E.M. Ransey, S. Dey, S. Das and M. Macbeth. Carnegie Mellon Univ. (988.3) 4:30
96.2 ‘Hidden’ states are pervasive in RNA folding: detection and dissection through mutate-and-map experiments.
Stanford Univ. Sch. of Med. and Stanford Univ. 4:55
sarcin/ricin domain of RNA. M.F. Bruist and C. Cavanaugh. Univ. of Sciences in Philadelphia. (989.1) 5:10
Alternative substrate kinetics of Escherichia coli ribonuclease P: determination of relative rate constants by internal competition. L.E. Yandek, H-C. Lin and M. Harris. Case Western Reserve Univ. (988.4) 5:25
96.3 RNA chaperone activity of dead-box ‘helicase’ proteins.
at Austin. 5:50
BIOCHEMISTRY SUNDAY 27 S U N 97. LIPID SIGNALING IN HEALTH AND DISEASE Symposium (Supported by an educational grant from Avanti Polar Lipids, Inc.) s un . 3:45 pm —B oston C onvention & e xhiBition C enter
, 254aB 3:45
Chair’s introduction. 3:50
PtdIns(4)P, the Golgi, and cancer. S.J. Field. UCSD.
4:15 Casein kinase II phosphorylation of yeast Pah1p phosphatidate phosphatase.
4:30
97.2 Regulation of glucocorticoid production by nuclear lipid metabolism.
4:55
Sphingosine kinase 1 is regulated by PPAR a in response to free fatty acids and mediates skeletal muscle IL-6 production and signaling in diet-induced obesity. J.S. Ross, W. Hu, B. Rosen, A.J. Snider, L.M. Obeid and L.A. Cowart. Med. Univ. of South Carolina, Boston Univ. Sch. of Med., Ralph H Johnson VA Ctr., Charleston, Stony Brook Univ. and Northport VA Ctr., NY. ( 813.18) 5:10
Rescue of sphingosine kinase-1-knockout phenotype by 2-acetyl-5-tetrahydroxybutyl imidazole following murine cardiac arrest is linked to changes in sphingosine-1- phosphate and behenoylceramide levels. E.V. Berdyshev, I.A. Gorshkova, V. Natarajan, H. Wang, D.G. Beiser and T.L. Vanden Hoek. Univ. of Illinois at Chicago and Univ. of Chicago. (813.17) 5:25
97.3 Sphingosine-1-phosphate signaling in inflammation and cancer.
Univ. Sch. of Med. 5:50
98. BIOENERGY Symposium s un . 3:45 pm —B oston C onvention & e xhiBition C enter
, 253C C haired : J. s tuBBe
3:45
Chair’s introduction. 3:50 98.1 Water oxidation chemistry of photosystem II. G. Brudvig. Yale Univ. 4:15
Mind the gap: long range charge transfer across the periplasm of Shewanella oneidensis.
Boston Univ., MIT and HHMI, Cambridge, MA. (787.1) 4:30
98.2 Biogenesis of the H-cluster of the [FeFe]- hydrogenase.
Univ.
4:55 Develop spatially-interactive multienzyme complex on selfassembled DNA nanostructures.
Biodesign at Arizona State Univ. (1002.4) 5:10
Kinetic and spectroscopic studies of bicupin oxalate oxidase and putative active site mutants. E.W. Moomaw, E. Hoffer, P. Moussatche, J. Salerno, M. Grant, B. Immelman, R. Uberto, A. Ozarowski and A. Angerhofer. Kennesaw State Univ., Univ. of Florida and Natl. High Magnetic Field Lab., Tallahassee.
5:25
98.3 Crystallographic snapshots of metalloenzyme complexes involved in biological carbon dioxide sequestration.
Michigan. 5:50
99. MECHANISMS OF CELL GROWTH AND AUTOPHAGY REGULATION Symposium s un . 3:45 pm —B oston C onvention & e xhiBition C enter
, 253B C haired : J. s. G uKinD
3:45
Chair’s introduction. 3:50 99.1 AMPK and mTOR in nutrient signaling and autophagy regulation.
4:15
A tumor suppressor complex withGAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1.
L. Bar-Peled, L. Chantranupong, A. Cherniack, W. Chen, K. Ottina, B. Grabiner, E. Spear, S. Carter, M. Meyerson and D.M. Sabatini. Whitehead Inst. for Biomed. Res., Broad Inst. of Harvard and MIT, John Hopkins Med. Sch., Dana-Farber Cancer Inst. and HHMI, Cambridge, MA.
4:30
99.2 Formation and maturation of the autophagosome.
4:55
Caveolin-1 is a critical determinant of autophagy and oxidative stress. N. Romero, T. Shiroto, H. Kalwa, J. Sartoretto, T. Sugiyama and T. Michel. Brigham and Women’s Hosp., Harvard Med. Sch. (831.21) 5:10
Control of mitochondria destiny by autophagy and a novel mitochondrial dynamics.
Indiana Univ. Sch. of Med. and Univ. of Kansas Med. Ctr. (832.3) 5:25
99.3 Reconstitution of the class III phosphatidylinositol-3-kinase in autophagy.
California, Berkeley. 5:50
100. NAVIGATING MID-CAREER TRANSITIONS Symposium s un . 3:45 pm —B oston C onvention & e xhiBition C enter
, 251 C haired : D. z uK 3:45 Chair’s introduction. 3:50
Mid-career adventure: making a successful transition.
4:20
UF CPET: professional development for secondary science teachers. H.A. Darwiche, J. Bokor, D. Joseph and M.J. Koroly. Univ. of Florida. (838.7) 4:35
100.2 One life scientist’s experience with mid-career transitions.
OR.
5:05 A picture is worth a thousand data points: an analysis of textbook visualizations in the molecular life sciences. E. Offerdahl and J. Arneson. North Dakota State Univ.
(838.13) 5:20
100.3 From mom to prof: make an effort. O.J. Finn. Univ. of Pittsburgh. 5:50
SUNDAY BIOCHEMISTRY 28 101. WELCOME RECEPTION SPONSORED BY THE ASBMB MINORITY AFFAIRS COMMITTEE Special Event s un . 6:30 pm —W estin B oston W aterFront h otel
, C ommonWealth B allroom
The ASBMB Minority Affairs Committee welcomes PI’s, industry professionals, educators, trainees and undergraduates to enjoy a networking and mentoring reception. Graduate Minority Travel Award recipient research posters will be on display.
s un . 8:00 am —B oston C onvention & e xhiBition C enter
, 157aBC C haired : J. e rDman
C oChaired : D. B alentine
Clinical Nutrition 8:00 Introduction. D. Balentine. Unilever. 8:05
Elements to consider in developing a path forward for bioactive components. K. Ellwood. Consultant. 8:25
Flavonoids and their contribution to health: a look at the scientific support. F. Hu. Harvard Sch. of Publ. Hlth. 8:45
Flavonoids as a case study. J. Dwyer. Tufts Univ. 9:05
Intake recommendations for dietary bioactives: Have we made progress in the last 20 years? J. Erdman. Univ. of Illinois at Urbana-Champaign. 9:45 Where to now? A panel discussion. R. M. Russell. Tufts Univ. and NIH. 105. EXPLORING CULTURE IN THE WORLD OF INTERNATIONAL NUTRITION AND NUTRITION SCIENCES Symposium (Sponsored by: Global Nutrition Council) s un
am —B oston C onvention & e xhiBition C enter
, 151aB C haired : D. h umphries
Global and Public Health Nutrition 8:00 Introduction. D. Humphries. Yale Univ. 8:05
A political economy of food security measurement: notes from the field. M. C. Stefani, A. Herforth. Stony Brook Univ., World Bank. Nutrition 102. BEVERAGES AND HEALTH: BEYOND WATER Special Event (Sponsored by: PepsiCo.) s un
am —W estin B oston
W aterFront h otel
, h arBor B allroom
ii/iii 103. ROLE OF GUT NUTRIENT SENSING IN METABOLIC DISEASES Symposium (Supported by educational grants from Lucta, Bristol- Myers Squibb and AstraZeneca) s un . 8:00 am —B oston C onvention & e xhiBition C enter
, B allroom e ast
C haired : D. B urrin
Biochemical, Molecular and Genetic Mechanisms 8:00
Chemosensing in the gut: nutrients, microbiota and the gut-brain axis. H. Raybould. Sch. of Vet. Med., Univ. of California, Davis. 8:30 Gut hormone responses to bariatric surgery impacts treatment of obesity and type 2 diabetes. A. Miras. Imperial Col. of London. 9:00 Metabolic improvements after bariatric surgery: role of the gut-brain axis. D. Sandoval. Univ. of Cincinnati. 9:30
Role of GLP-1 in body weight regulation: lessons from human trials. A. Astrup. Univ. of Copenhagen. Are you Tweeting about EB 2013? To Tweet use #EB2013 Be sure to follow EB on Facebook
and Twitter .
29 S U N 8:40
From efficacy research to large-scale impact on undernutrition: the roles of community, disciplinary and organizational cultures.
Cornell Univ., London Sch. of Hyg. and Trop. Med. 9:15 The role of critical discourse analysis in understanding food policy: why narratives matter. L. Jarosz, S. Young. Univ. of Washington, Cornell Univ. 9:45 Conclusion. 106. EPIDEMIOLOGICAL RESEARCH ADDRESSING DIET AND HEALTH OUTCOMES I Minisymposium (Sponsored by: Nutrition Epidemiology RIS) s un
am —B oston C onvention & e xhiBition C enter
, 152 C haired : l.m. t roy
C oChaired : a. m illen
8:00 106.1 Changes in coffee intake and subsequent risk of type 2 diabetes in women.
and Saw Swee Hock Sch. of Publ. Hlth., Singapore. 8:15
Intakes of dietary flavonoid sub-classes and incidence of type 2 diabetes.
Norwich Med. Sch., Univ. of East Anglia, U.K., Massachusetts Gen. Hosp. and Tufts Med. Ctr. 8:30
106.3 Meal and snack patterns associated with biomarkers of glucose metabolism, diet quality and weight status in U.S. adults. D. Shin, S.J. Song, H-Y. Paik and W.O. Song. Michigan State Univ. and Seoul Natl. Univ. 8:45
106.4 Prospective associations of biomarkers of glucose metabolism and obesity-related cancers in the Framingham Heart Study (1971-2008). N. Parekh, Y. Lin, M. Vadiveloo, R. Hayes, G. Lu-Yao and Y. Lin. NYU, UMDNJ, Piscataway, NYU Med. Ctr. and Cancer Inst. of New Jersey, New Brunswick. 9:00
106.5 Effect of dairy intake on bone mineral density is only beneficial with higher vitamin D intakes: the Framingham Original Cohort. S. Sahni, K.L. Tucker, D.P. Kiel, L. Quach, V. Casey and M.T. Hannan. IFAR, Hebrew SeniorLife and Harvard Med. Sch. and Notheastern Univ. 9:15
Dietary patterns, omega-3 fatty acids intake from seafood and high anxiety symptoms during pregnancy: findings from the Avon Longitudinal Study of Parents and Children.
of Bristol, Univ. of Illinois at Chicago and NIAAA, NIH, Rockville. 9:30
Are physical activity levels linked to nutrient adequacy? Implications for cancer risk.
Care, Calgary and Univ. of Alberta. 9:45
The impact of preschoolers on household food and beverage purchases changed significantly between 2000 and 2011. C.N. Ford, S. Ng and B.M. Popkin. Univ. of North Carolina at Chapel Hill. 107. GLOBAL NUTRITION: BIOMARKERS FOR ASSESSING INTERVENTIONS Minisymposium (Sponsored by: Global Nutrition Council) s un
am —B oston C onvention & e xhiBition C enter
, 153a C haired : D. l ópez
De r omaña C oChaired : s. h ess
8:00 107.1 High plasma homocysteine increases risk of metabolic syndrome in 6- to 8-year-old children in rural Nepal.
of California, Davis. 8:15
Maternal and breastmilk vitamin B12 correlated with infant status but was not influenced by maternal supplementation among HIV- infected Malawian women in the Breastfeeding, Antiretrovirals and Nutrition Study.
Davis, Univ. of North Carolina at Chapel Hill, UNC Proj., Malawi and Ctrs. for Dis. Control and Prevent. 8:30
107.3 Zinc absorption from Sprinkles™ is not affected by iron in Kenyan infants in malaria endemic area.
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