1 friday, april 19 Biochemistry and Molecular Biology asbmb graduate and postdoctoral travel award keynote lecture special Session

Career Development

Physiology

64.  REFRESHER COURSE: IMMUNOLOGY FOR THE 

PHYSIOLOGIST

Symposium

(Sponsored by: APS Education Committee)

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Education

8:00 

Crash course in adaptive immunity. 

R. Kedl. Univ. of 

Colorado Denver.

9:00 

Crash course in innate immunity. 

D. Mosser. Univ. of 

Maryland College Park.

10:00 

Neural control of immune system function. 

P. Olofsson. 

The Feinstein Inst. for Med. Res., Manhasset, NY.

11:00  Immune control of the cardiovascular system. 

D. G. 

Harrison. Vanderbilt Univ. Sch. of Med.

65.  MICROCIRCULATORY SOCIETY PRESIDENT’S 

SYMPOSIUM I: CELLULAR AND NON-

CELLULAR MODES OF COMMUNICATION 

ACROSS THE BLOOD VESSEL WALL

Symposium

(Sponsored by: The Microcirculatory Society)

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9:00 

Endothelial-vascular smooth muscle cell communication: 

integrating signals across the vascular wall. 

K. A. 

Dora. Univ. of Oxford.

9:30  Bidirectional communication between extracellular 

matrix proteins and vascular smooth msucle cells. 

G. 

A. Meininger. Univ. of Missouri-Columbia.

10:00 

Immune cells in the artery wall. 

K. Ley. La Jolla Inst. for 

Allergy and Immunol.

PHARMACOLOGY/PHYSIOLOGY SATURDAY 

19

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10:30  Impact of hemorrhagic stroke on neurovascular 

communication. 

G. Wellman. Univ. of Vermont.

11:00  The pannexin1/alpha-adrenergic axis can directly 

regulate blood pressure. 

B. E. Isakson. Univ. of 

Virginia.

66.  HOW TO BE A SCIENCE ADVOCATE IN YOUR 

OWN BACKYARD

Symposium

(Sponsored by: APS Science Policy Committee)

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Career Development

Science Policy

1:00 

Case studies: local and national programs. 

G. C. 

Schatteman. Univ. of Iowa.

1:25 

Facilitating outreach through research universities. 

T. 

Leshan. Northeastern Univ.

1:50 

The student perspective and action in the science policy 

intersection. 

M. R. Sukup Jackson. MIT.

2:15 

Getting a conversation started. 

W. T. Talman. Univ. of 

Iowa, VA Med. Ctr.

2:40 

General discussion.

67.  RODENT EXPERIMENTATION

Workshop

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Education

1:00 

Energy balance 101. How do you normalize data? Do 

obese mice really have a lower energy expenditure? 

O. P. McGuinness. Vanderbilt Univ. Sch. of Med.

1:30 

In vivo bioluminescence imaging of gene expression. 

C. 

N. Young. Cornell Univ.

2:00 

Implementing optogenetics in rodent models: conscious, 

anesthetized and in vitro. 

R. Stornetta. Univ. of 

Virginia Hlth. Syst.

2:30 

Novel modalities for in vivo analysis of rodent cardiac 

performance. 

K. Hutchinson. Univ. of Arizona.

68.  MICROCIRCULATORY SOCIETY PRESIDENT’S 

SYMPOSIUM II: RAPID FIRE DISCUSSION OF 

NOVEL TRENDS

Symposium

(Sponsored by: The Microcirculatory Society)

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2:00 

Association of two polymorphisms in the Cx40 promoter 

with hypertension and left ventricular hypertrophy. 

K. 

Schmidt, F.J. Kaiser, H. Schunkert, J. Erdmann and 

C. de Wit. Univ. of Lübeck and Tech Univ. Munich. 

(678.10)

2:10  VEGF-C induces lymphangiogenesis in the rat 

mesentery culture model. 

R.S. Sweat and W.L. 

Murfee. Tulane Univ. (681.10)

2:20  Sensory nerve-dependent prolonged opening 

of pannexin-1-based channels controls eNOS 

phosphorylation in mesenteric arteries. 

P. Gaete, M. 

Lillo and X. Figueroa. Pontifical Catholic Univ. of 

Chile. 

(901.2)

2:30 

Histamine is novel endothelium-derived relaxing factor 

in rat mesenteric lymphatic vessels. 

A. Gashev, I. 

Tsoy Nizamutdinova, T. Nagai, D. Maejima, E. 

Bridenbaugh, S. Thangaswamy and V. Chatterjee. 

Texas A&M Hlth. Sci. Ctr., Col. of Med. and Shinshu 

Univ. Sch. of Med., Japan. 

(681.4)

2:40 

Basal nitric oxide production in mouse collecting 

lymphatics does not enhance contractile activity. 

J.P. 

Scallan and M.J. Davis. Univ. of Missouri-Columbia. 

(681.9)

2:50 

Dynamics of nitric oxide activity are sufficient and 

optimal to drive lymphatic pumping. 

C. Kunert, T.P. 

Padera and L.L. Munn. Massachusetts Gen. Hosp./

Harvard Med. Sch. 

(681.1)

3:00 

LPS-mediated decreases in immune cells recruitment 

on or near lymphatics impairs lymphatic contractility. 

S. Chakraborty, D.C. Zawieja and M. Muthuchamy. 

Col. of Med., Texas A&M Hlth. Sci. Ctr. 

(681.5)

3:10 

Flow modulation and recruitment in a theoretical 

model for blood flow regulation in heterogeneous 

microvascular networks. 

B.C. Fry and T.W. Secomb. 

Univ. of Arizona. 

(898.19)

3:20  Multiscale computational models of microvascular 

reactivity from ion channels to intercellular signaling. 

A. Kapela, J. Parikh and N.M. Tsoukias. Florida Intl. 

Univ. 

(901.8)

3:30 

Impact of redox signaling inhibition on collateral growth 

in young, healthy rats. 

S.J. Miller, M. Wenning, R.G. 

Bills, P. Sliva, C.A. Labarrere, M.R. Kelley, M.L. 

Fishel and J.L. Unthank. Indiana Univ. and Methodist 

Res. Inst., Indianapolis. 

(685.2)

3:40 Monocyte recruitment during microvascular 

arteriogenesis is induced by altered flow and 

influenced by proximity of venules to collateral 

arterioles. 

A. Bruce, J.K. Meisner, R.J. Price and 

S.M. Peirce. Univ. of Virginia. (685.8)

3:50 

Helium ion microscopy of the rodent kidney and male 

reproductive tract. 

T.G. Paunescu, C. Huynh, L. 

Lechner, B. Goetze, L. Stern, S. Breton and D. 

Brown. Massachusetts Gen. Hosp., Harvard Med. 

Sch. and Carl Zeiss Microscopy LLC, Peabody, MA. 

(683.1)

4:00 

Altered electrical reactivity of endothelial tubes with 

aging: role of mitochondria and Ca

2+

-activated 

K

+

channels. 

E.J. Behringer and S.S. Segal. Univ. of 

Missouri-Columbia. 

(679.1)

SATURDAY PHYSIOLOGY

20

69.  DISTILLING YOUR MESSAGE FOR THE PUBLIC

Symposium

(Sponsored by: APS Communications Committee)

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Career Development

Have you ever been asked to describe your research to a 

congressperson, media person, fundraiser, parent, or potential 

philanthropist? The Center for Communicating Science (CCS) 

from Stony Brook University School of Journalism was founded in 

2009 to help scientists learn to communicate more clearly, vividly 

and conversationally with the public. Actor Alan Alda is a founding 

member of the Center. This interactive session facilitated by CCS 

staff will help participants learn to speak clearly and vividly about 

their work and explain why it matters that non-scientists can 

understand. Activities will include finding common ground with 

your audience, communicating at different levels of complexity 

for different audiences, and answering questions from the media 

or the public. Come join the APS Communications Committee in 

becoming better communicators of our science!

70.  BIOINFORMATICS AND MODELING 101: HOW 

TO USE YOUR OFFICE COMPUTER FOR 

DISCOVERING/MODELING PHYSIOLOGICAL 

NETWORKS OF YOUR FAVORITE GENES

Workshop

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Education

3:15 

Bioinformatic network/pathway analyses: finding where 

your favorite genes/proteins hangout. 

M. Dwinell. 

Med. Col. of Wisconsin.

3:45 

Computer simulations and applications in the virtual 

physiological rat project. 

D. A. Beard. Med. Col. of 

Wisconsin.

4:15 

Simulation tools for computational physiology. 

P. Hunter. 

Auckland Bioengin. Inst.

4:45 

Systems bioinformatics for cancer genomics. 

S. Lee. 

Ewha Woman’s Univ., South Korea.

71.  TRAINEE AWARD FINALISTS SESSION AND 

DATA DIURESIS

Award

(Supported by an educational grant from Data Sciences, 

International and Juan Carlos Romero Foundation)

(Sponsored by: APS Water and Electrolyte Homeostasis 

Section)

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anD

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 (D

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)

3:15 

Ang (1-7) has a greater contribution to the blood 

pressure lowering effects of AT1 receptor blockade 

in female spontaneously hypertensive rats compared 

to males. 

M. Zimmerman and J. Sullivan. Georgia 

Regents Univ. 

(904.3)

3:25 

Acute kidney injury following orthopedic trauma in obese 

Zucker rats. 

P. Mittwede, L. Xiang, J. Clemmer, S. 

Lu, A. Gowdey and R. Hester. Sch. of Med., Univ. of 

Mississippi Med. Ctr. 

(1114.6)

3:35  Indoleamine-2,3-dioxygenase restrains hypertension 

induced by angiotensin II in rats fed a high salt diet. 

K. 

H. Yiew, S.K. Yoon, L. Huang, C. Jin, A.L. Mellor and 

D.M. Pollock. Georgia Hlth. Sci. Univ. (1115.2)

3:45 Break.

4:00 

Endoplasmic reticulum stress is upstream of angiotensin-

II-induced reactive oxygen species formation in the 

subfornical organ. 

C.N. Young, G. Wang, C. Iadecola, 

A.L. Mark and R.L. Davisson. Cornell Univ., Weill 

Cornell Med. Col. and Univ. of Iowa. 

(906.15)

4:10 

Mechanisms of shear stress mediated nitric oxide 

production by inner medullary collecting duct cells. 

K.A. Hyndman and J.S. Pollock. Georgia Hlth. Sci. 

Univ. 

(1115.10)

4:20 

Humoral immune system activation promotes the 

development of hypertension. 

K.W. Mathis, K. 

Wallace, B. Lamarca and M.J. Ryan. Univ. of 

Mississippi Med. Ctr. 

(906.4)

4:30 Break.

4:35 

Mitochondrial superoxide in pro-hypertensive T-cell 

activation. 

R.R. Nazarewicz, A.E. Dikalova, A.T. 

Bikineyeva, D.G. Harrison and S.I. Dikalov. 

Vanderbilt Univ. Med. Ctr. 

(906.8)

4:40 

Sex difference in low dose of angiotensin (ANG) II 

sensitizing effect on pressor effect of subsequent high 

dose of ANG II. 

B. Xue, Z. Zhang, F. Guo, M. Hay 

and A.K. Johnson. Univ. of Iowa and Univ. of Arizona. 

(904.6)

4:45 

Overexpression of renin in the collecting duct causes 

hypertension. 

N. Ramkumar, J. Ying, D. Stuart and 

D.E. Kohan. Univ. of Utah. (909.4)

4:50 

Real-time electrochemical detection of endogenous 

substance release in freshly isolated organs. 

O. 

Palygin, V. Levchenko, D.V. Ilatovskaya, T.S. Pavlov, 

R.P. Ryan, A.W. Cowley, Jr. and A. Staruschenko. 

Med. Col. of Wisconsin. 

(910.16)

4:55 

Perinatal taurine depletion increases oxidative stress in 

adult female rats. 

W. Lerdweeraphon, J.M. Wyss, T. 

Boonmars and S. Roysommuti. Khon Kaen Univ., 

Thailand and Univ. of Alabama at Birmingham. 

(908.4)

Please Silence Your  

Cell Phones during  

Sessions

PHYSIOLOGY SATURDAY 

21

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5:00  Brain (pro)renin receptor knockdown modulates 

the body fluid homeostasis during angiotensin II-

dependent hypertension. 

T. Cao, W. Li, D. Seth and Y. 

Feng. Tulane Univ. (906.20)

5:05 

Endothelin B receptor protects against endoplasmic 

reticulum stress-induced renal damage. 

C. De Miguel, 

J.L. Hobbs, D.M. Pollock and J.S. Pollock. Georgia 

Hlth. Sci. Univ. 

(906.5)

5:10 

Vasopressin affects renal tubular dynamics during 

hemorrhagic shock resuscitation. 

C.F.T. Uyehara, J. 

Sarkar, L-A.M. Murata, A.K. Sato, W.M. Ichimura, 

C.A. Hernandez and C.L. Allen. Tripler Army Med. 

Ctr., HI. 

(904.11)

5:15 

Enhanced sensitivity of NKCC2 to 

b-adrenergic receptor 

stimulation in TALs from Dahl salt-sensitive rats. 

G.R. 

Ares, M.Z. Haque and P.A. Ortiz. Henry Ford Hosp. 

(910.2)

72.  PHYSIOLOGY IN PERSPECTIVE — THE WALTER 

B. CANNON MEMORIAL AWARD LECTURE

(Supported by an educational grant from Sucampo AG)

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Title:  Is Physiology Redundant?

 

Speaker: 

M. J. Joyner.

 Mayo Clin.

Experimental Biology exhibitors offer the best tools and  

resources available in research today!

Join the exhibitors at 10:00 

am

 for coffee and 2:00 

pm

 for snacks and  

learn the latest and greatest from more than 300 companies.

SATURDAY PHYSIOLOGY

22

SUNDAY, APRIL 21

Across Societies – Experimental Biology

10:00  Postdocs: what should you be looking for and how to 

find them. 

A. Green.

11:00  Revealing your character through your resume. 

J. 

Blumenthal.

11:00 

Beyong the bench: preparing for your career transitions 

in the life sciences. 

J. Tringali.

11:00 

Get up with something on your mind. 

H. Adams.

1:00 

Ten ways to get lucky in the job search. 

P. Clifford, J. 

Lombardo.

1:00 

Professional development for PhDs. 

A. Green.

1:00 

Managing conflict. 

S. Milgram, L. Conlan.

1:30  Global interview skills: a practice workshop for 

international candidates. 

D. Behrens.

1:30 

Professionalism for students in today’s world. 

H. Adams.

2:15 

Transforming your CV. 

N. Saul.

3:00 

Job hunting in the biotech industry. 

B. Lindstaedt.

3:00 

Making teams work. 

S. Milgram, L. Conlan.

3:30 

Economics and your job search. 

J. Tringali.

4:00 

Job search in academia and industry. 

D. Behrens.

4:00  Developing your core message/elevator pitch. 

J. 

Lombardo.

73.  CAREER DEVELOPMENT SEMINARS AND 

WORKSHOPS

Workshop

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Career Development

The following Seminars and Workshops will be held in the 

EB2013/FASEB Career Center. There is no fee or pre-registration 

associated with the workshops and seminars; just walk in and sit 

down!

Critiquing of CV/Resumes is by appointment and starts at 

9:30 AM on Sunday and continues until 5:00 PM on Wednesday. 

Sign up on-site in the EB2013/FASEB Career Center, Hall B.

9:15 

The right attitude and behaviors while job searching - 

from the resume to the job. 

J. Blumenthal.

9:30 

Talking about yourself: interviewing well. 

N. Saul.

9:30 

Networking: a required life skill. 

H. Adams.

9:30 

Workplace dynamics I/II. 

S. Milgram, L. Conlan.

Anatomy

75.  CELL BIOLOGY

Plenary

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Cell Biology

10:30 

75.1 

Structural and functional evolution of epithelia 

and cell-cell adhesion complexes. 

W.J. Nelson. Stanford Univ.

11:30 

75.2 

Regulation of early stages in clathrin-mediated 

endocytosis revealed by quantitative analyses in living cells. 

S.L. Schmid, F. Aguet, C. Antonescu, M. Mettlen and G. 

Danuser. Univ. of Texas Southwestern Med. Ctr., Harvard Univ. 

Med. Sch. and Ryerson Univ., Toronto.

74.  EVOLUTIONARY/DEVELOPMENTAL BIOLOGY

Plenary

(Cosponsored by: AAA Fellows Legacy Fund)

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ChoenWolF

Developmental Biology

8:00 

74.1 

Fossils, genes, and the origin of organs. 

N.H. 

Shubin. Univ. of Chicago.

(8:40 

74.2 

The evolution of arthropod appendages. 

N.H. 

Patel. Univ. of California, Berkeley.

9:20 

74.3 

Evolution of vertebrate limb morphology. 

C.J.