AN-1303-035
ASSESSMENT OF OXYGEN STATUS IN CRITICAL PATIENTS WITH SYSTEMIC INFLAMMATORY
REACTION
Berezhnoy S.G., Lukach V.N., Tsygankov P.V., Malaya N.S., Furmanova T.Yu.
City Clinical Hospital of Emergency Medical Service No 1, 644112, Omsk, Russia; Omsk State Medical
Academy, 644112, Omsk, Russia
Diagnostic ability of alveolar-arterial oxygen gradient (A-aDO2) and respiratory index (RI) for acute
respiratory distress syndrome was underestimated before recent time. 68 patients with severe
inhomogeneous lung injure (severe concomitant trauma, pneumonia, and pancreonecrosis) were involved in
the study. Patients were divided into two groups (basic group - 34 patients and control group - 34 patients).
There were no differences in data of severity-of-disease by APACHE II and SOFA scales and J.F. Murrey
lung injury score in both groups. Conventional volume controlled and pressure control respiratory techniques
were used in patients of control group. Multi-level ventilation with three levels was used in patients of basic
group. Blood gas containing, A-aDO2 and RI were studied. Gas status data improved both to gas exchange
effi cacy in patients of basic group. The data were signifi cant different in the control group. Thus multilevel
ventilation improves alveolar ventilation and arterial oxygenation, decreases pulmonary shunt and lung injury
and improves respiratory lung functions.
Key words: alveolar-arterial oxygen gradient, respiratory index, shunt fraction, acute respiratory distress
syndrome, oxygen status, multi-level ventilation
AN-1303-040
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