Another Bias Correction Method John Ashburner



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Another Bias Correction Method


Introduction

  • MR images are usually corrupted by a smoothly varying artefact that modulates the intensity of the image. This poster presents a method for removing most of this artefact.

  • Most current methods are either:

    • Parametric: Bias correction is incorporated into a mixture of Gaussians type approach, possibly as a refinement of a tissue classification algorithm.
      • Bias correction component is normally applied to log-transformed intensities (e.g. Wells III et al, 1996; Van Leemput et al, 1999).
    • Non-parametric: Bias correction applied to histograms of intensities in order to maximise entropy.
      • Most widely used approach is applied to histograms of log-transformed intensities (Sled et al, 1998).
      • Another approach minimises entropy of the histogram of the original intensities, with a modification to preserve the average intensity in the image (Mangin, 2000).

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