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Student will be able to describe a variety of applications for genomics.
3.4 Language Objectives
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Student will be able to identify and define topic key vocabulary.
•
Student will be able to use Reading Resources to identify word, sentence, and paragraph
grammar structures.
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Student will be able to use Reading Resources to practice Reading Resource strategies.
•
Student will be able to restate (orally or written) Science and Biology definitions and main ideas
using content-specific terms.
•
Student will be able to organize information using a variety of graphic organizers according to
content-specific expectations (e.g., Steps of The Scientific Method).
3.4 Reading Resources
#1 Isolation of Nucleic Acids
#2 Whole Genome Sequencing
#3 Applying Genomics
A.
Warm-Up
Talk about the issues with a partner.
1)
What is a genomics?
2)
What is a nucleic acid?
3)
What is a polymer?
3.4 Reading Resource #1:
Isolation of Nucleic Acids
To study or manipulate nucleic acids, DNA from cells must first be extracted. Different techniques are
used to extract various types of DNA (Figure 50). Most nucleic acid extraction methods involve breaking open
the cell and then using enzymatic reactions to destroy any unwanted macromolecules. A detergent solution
containing buffering compounds is used to break open cells. Enzymes are used to inactivate macromolecules
such as proteins and RNA to prevent degradation and contamination. The DNA is then extracted from solution
using alcohol. Because it is composed of long polymers, the resulting DNA forms a gelatinous mass.
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