Hellp syndrome may it be a separate entity?

increase in Bilirubin and lactic dehydrogenase levels.

Etiology and Pathogenesis

• The elevated liver enzyme levels in the syndrome are thought to be secondary to obstruction of hepatic blood flow by fibrin deposits in the sinusoids. This obstruction leads to periportal necrosis and, in severe cases, intrahepatic hemorrhage, subcapsular hematoma formation or hepatic rupture.

Etiology and Pathogenesis

• The thrombocytopenia has been attributed to increased consumption and/or destruction of platelets.

Clinical Presentation

• 90%of patients present with generalized malaise,

• 65 % with epigastric pain,

• 30 % with nausea and vomiting,

• 31 percent with headache.