1
) and their perspective heterocyclic analogues (thienopyrimidines,
2
and
benzimidazoles,
3
), also new organometallic alkaloid-ferrocene hybrid molecules (
4
)
consisting different electron donating and electron withdrawing groups will be
discussed [4-6]:
Results of the influence of π-deficient and π-excessive rings, catalysts, synthesis of
the novel potent active compounds, reactions with electrophilic and nucleophilic
reagents, and formation of cross-coupling (Suzuki coupling) products,
mono
- and
double
- condensation products from ferrocene(di)carbaldehydes will be discussed.
References
1.
Sordella, R., D.W. Bell, D.A. Haber, J. Settleman,
Science
, 2004, 305, 1163-1167.
2.
Al-Suwaidan, I.A., A.M. Alanazi, A.A.M. Abdel-Aziz, M.A. Mohamed, A.S. El-
Azab.
Bioorg. Med. Chem. Lett.
, 2013, 23, 3935-3941.
3.
El-Subbagh, H.I., G.S. Hassan, S.M. El-Messery, S.T. Al-Rashood, F.A.M. Al-
Omary, Y.S. Abulfadl, M.I. Shabayek.
Eur. J. Med. Chem.
, 2014, 74, 234-245.
4.
Shakhidoyatov Kh. M., Elmuradov B. Zh.,
Chem. Nat. Compd.
, 2014, 50, 781.
5.
Elmuradov B. Zh., Kh. Shakhidoyatov., G. Dräger., H. Butenschön.
Eur. J. Org.
Chem.,
2016, 3, 483–492.
6.
Bozorov Kh.A.,
Jiang-Yu Zhao, Elmuradov B. Zh., Apar Pataer, Haji A. Aisa.
Eur.
J. Med. Chem.
, 2015, 102, 552-573 (Review).
Plenary presentation
13
Anti-inflamatuvar and Apoptotic DNA Fragmentation Activities of
White Pitaya Fruit Extracts Against Human Colon Cancer Cells
Dostları ilə paylaş: |
