Organizing co mmittee

COMPOSITION BASED ON THE GROWTH REGULATOR FLOROXAN 
WITH GLYCYRRHIZIC ACID FOR COTTON GROWTH 
 
R.P. Zakirova
1
, Khalikov S.S.
2
, Turaeva S.M.
1
, Kurbanova E.R.
1
, 
Chkanikov N.D.
2
 
1) S.Yu. Yunusov Institute of the Chemistry of Plant Substances Academy of sciences of 
the Republic of Uzbekistan st. Mirzo-Ulugbek, 77, 100170 Tashkent 
e-mail: [e-mail] 
2) Acad. A.N. Nesmeyanov Institute of the Organoelement Compounds, Russian 
Academy of Sciences, 119334 Moscow, st. Vavilov, 28/1;
e-mail: [e-mail] 
Floroxan is an original development of Institute of Organoelement Compounds 
named after A.N. Nesmeyanov RAS and its biological properties have been studied by 
scientists in Russia and Uzbekistan for several years as a promising plant growth 
regulator. For the first time, the unique properties of floroxan were noted by All-
Russian Research Institute of Phytopathology. specialists when studying it in the form 
of an aqueous solution on such crops as rapeseed, corn, and sunflower. The drug 
showed biological activity at doses up to 100 mg/ha, which did not allow it to be used 
as a separate drug on an industrial scale in agricultural practice. 
The work aims to develop drugs based on floroxan to stimulate the growth of crops. 
A fundamentally new approach to improving the properties of floroxan by its 
mechanochemical modification with glycyrrhizic acid (GA) is proposed. The choice of 
this polysaccharide is explained by the fact that GA has a complex of useful properties, 
namely, it has a high solubilizing ability and increased permeability through plant 
membranes. 
The study of the growth-stimulating activity of the drug based on a solid dispersion 
of floroxan and glycyrrhizic acid was carried out on hopscotch. Pre-sowing soaking of 
cotton seeds showed high efficiency of the drug in terms of germination, growth, and 
development of cotton, as well as the formation of its fruit elements compared to 
floroxan. The drug, when dissolved in water, forms a supramolecular complex that 
provides increased solubility, bioavailability, and absorption (penetration through plant 
membranes) of floroxan, and, consequently, a general increase in its biological activity. 
The drug, obtained by low-energy and waste-free one-stage technology, has a plant 
growth-stimulating activity that exceeds the activity of floroxan, is based on available 
domestic raw materials, is environmentally safe, stable during long-term storage, is 
highly soluble in water, and is convenient to use. 

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Poster presentation 
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