Poster presentation
159
COMPONENTS FROM THE PLANT Haplophyllum latifolium
Z. Ch. Abraeva
1
, A. R. Khurramov
1
, B. Nazarov
2
, Kh. A. Rasulova
1
,
Kh. M. Bobakulov
1
1) S.Yu. Yunusov Institute of the Chemistry of Plant Substances Academy of sciences of
the Republic of Uzbekistan st. Mirzo-Ulugbek, 77, 100170 Tashkent
e-mail: zuhro.chorievna@mail.ru
2) Samarkand State University Samarkand region, Uzbekistan 140104
Plants of the genus
Haplophyllum
A. Juss. (Rutaceae family) are represented on a
global scale by about 150 species distributed from the Mediterranean to Western
Siberia. There are 23 species of
Haplophyllum
growing on the territory of Central Asian
countries. Plants of this genus attract the attention of researchers as potential sources of
biologically active substances contain quinoline, furanoquinoline alkaloids and amides,
which are promising and rich in sources of coumarins, flavonoids, lignans and essential
oils.
Haplophyllum latifolium
Kar. & Kir. (whole-leaved broadleaf) is a perennial herb
that grows in the Tashkent, Samarkand and Kashkadarya regions. The aerial part of the
H. latifolium plant collected in the Tashkent region was extracted with ethanol.
Gasoline, chloroform, ethyl acetate and ethanol fractions were obtained from the
ethanol extract. As a result of separation of the ethyl acetate fraction of H. latifolium on
a column, were obtained kusurokinin with a temperature of 183-184°C and haplamid
172-173
C as well as substances haplamidin with a temperature of 139-140°C,
dimethylmatairesinol and daucosterol. The chemical structure of isolated compounds
was elucidated by studying their spectral data of
1
H and
13
C NMR, as well by HSQC,
HMBC and COSY experiments followed by comparison with literature data.
Haplamidin Dimethylmatairesinol
Daucosterol
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