Organizing co mmittee

 
References: 
1.
X. Zhao, 
et al. 
Biomass-based chemical looping technologies: The good, the bad 
and the future. Energy Environ. Sci., 10 (9) (2017), pp. 1885-1910.
2.
S.V. Vassilev, 
et al.
An overview of the organic and inorganic phase 
composition of biomass Fuel, 94 (3) (2012), pp. 1-33.
3.
State Pharmacopoeia of the Republic of Uzbekistan. First edition. Volume 1, 
part 1., Tashkent. 2021. p. 816. 

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Poster presentation 
169 
POLYSACCHARIDES OF Ficus carica 
 
M.A. Kuronboeva, K.S. Zhauynbaeva, A.A. Azamatov, F.M. Tursunkhodzhaeva 
 
S.Yu. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences 
Republic of Uzbekistan, 100170, Tashkent, M. Ulugbek st., 77 
e-mail: [e-mail] 
The plant 
Ficus carica
L. (family Moraseae) is widely distributed in the Republic of 
Uzbekistan. It is cultivated in all regions, especially in the Ferghana Valley. 
Furocoumarins were found in the leaves (in dry - up to 2%) psoralen and bergapten, 
which have a photosensitizing effect, like hogweed. In medical practice, the drug 
"Psoberan" from fig leaves is approved for the treatment of skin diseases - vitiligo and 
alopecia areata. However, little is known about the biological activity of the 
polysaccharides of this plant in the literature [1-3]. 
In this regard, the study of 
F. carica
L. polysaccharides was of great interest. 
We isolated water-soluble polysaccharides (WSPS) from air-dry raw materials with a 
yield of 3.5%, which are an amorphous cream-colored powder, readily soluble in water, 
η 
rel
= 1.1 (with 1% H
2
O). The molecular weight is 43 kDa. In the VRPS hydrolyzate, 
gas-liquid chromatography (GC) revealed galactose, xylose, arabinose, rhamnose, and 
glucose. The content of uronic acids was determined by the carbazole method, it is
34%. 
Therefore, the original VRPS is a mixture of neutral and acidic polysaccharides. In the 
IR spectra of VRPS there were characteristic absorption bands at 3282,1568,1405, 
1260, 1086, 891, 787, 657см
-1
. 
The biological activity of 
F. carica
VRPS was studied in a model of formalin 
arthritis. At the same time, VRPS showed the most pronounced anti-inflammatory effect 
at a dose of 150 mg/kg p/o (58%), inferior to the effect of ketoprofen at a dose of 5 
mg/kg p/o (70%) and superior to diclofenac at the same dose (50%). 
Thus, 
F. carica
VRPS is a heterogeneous polysaccharide that is of interest as a 
potential source of anti-inflammatory agents. 
Reference 
1. Flora of Uzbekistan volume-II. Publishing House of the Academy of Sciences of 
the Uzbek SSR, p.88 
2. B.S. Okundedaev, Kh.M. Bobokulov, R.F. Mukhamatkhanova, S.Z. Nishanbaev, I. 
J. Shamyanov, Pharmaceutical Journal, 3, 12 (2020) 
3.
Olufemi Emmanuel Bankefa, Ruth Adefolakemi Gabriel-Ajobiewe, Olubunmi 
Evelyn Ajayi1, Simbiat Olufunke Ayilara-Akande1, Seye Julius Oladeji, Gbenga Victor 
Kayejo, Journal of Food Safety and Hygiene,