Organizing co mmittee

 

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Poster presentation 
92 
CHEMICAL COMPONENTS OF Ferula lapidosa 
 
Kh. I. Khasanova
1
, A.U. Babekov
2
, K. A. Eshbakova
1
, K.K. Turgunov
1
,
B. Tashkhodzhaev
1
 
1) 
S.Yu. Yunusov Institute of the Chemistry of Plant Substances Academy of sciences of 
the Republic of Uzbekistan st. Mirzo-Ulugbek, 77, 100170 Tashkent 
e-mail: [e-mail]; 
2) Osh State Pedagogical University. A.Zh.Myrsabekov, 723500, Osh st. Isanov 73,
fax: [phone], Kyrgyzstan. 
e-mail: [e-mail]
 
 
The plant
 Ferula lapidosa
of the Umbrella family (
Apiaceae
) is endemic to Central 
Asia. The roots of 
F. lapidosa
were collected during the flowering period in the 
Republic of Kyrgyzstan. Dried and crushed roots of 
F. lapidosa
were extracted with 
96% alcohol.
The condensed alcohol extract was separated by column chromatography 
with systems of a gradual eluting benzene and ethyl acetate (9:1-1:1). Three compounds 
were isolated by column chromatography. Isolated compounds identified based on their 
spectroscopic data (IR, MS, 
1
H, 
13
C NMR) XRA and by comparison with compounds 
described in the literature, with β-stigmasterol, β-sitosterol and sesquiterpene lactone 
3,6,9-trimethylazulenol[4,5-b] furan-2,7-dione. 
These compounds from 
F. lapidosa 
are isolated for the first time. 
β-stigmasterol

β-sitosterol 
3,6,9-trimethylazulenol[4,5-b]furan-2,7-dione 
O
O
H
3
C
H
3
C
CH
3
O

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Poster presentation 
93