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Abstracts ICPS 2023

References 
1.
Struthers, H., Mindt, T. L. Schibli, R. (2010). Dalton Trans. 39, 675-696. 
2.
Morzherin, Y., Prokhorova, P. E. Fan, Z. (2011). Pure Appl. Chem. 83, 715p 
3.
Аbdugafurov I.A., Qirgizov F.B., Ortikov I.S. (2021)// Eur.Jour.Chem. № 12(1). 
4.
Spackman M. A., Jayatilaka, D. // Cryst. Eng. Comm, 11, 2009, p. 19–32. 
Fig. 1. View of the three-dimensional Hirshfeld 
surface of title compound mapped over d
norm
 


Poster presentation 
265 
A SIMPLE AND CONVENIENT METHOD FOR 
ARYLSULFONYLATION OF 2,5-DIMETHYLBENZIMIDAZOLE 
 
K. Abdireymov, B. J. Elmuradov
 
S.Yu. Yunusov Institute of the Chemistry of Plant Substances Academy of 
sciences of the Republic of Uzbekistan st. Mirzo-Ulugbek, 77, 100170 Tashkent 
Benzimidazoles and their derivatives have a wide spectrum of biological activity. For 
example, among heterocyclic compounds containing a benzimidazole skeleton, there are 
a number of effective drugs that are recommended for use in agriculture (
albendazole, 
carbendazim, benomyl
) and medicine (
dibazole
). Therefore, conducting targeted 
research on the synthesis and study of the biological activity of substituted 
benzimidazoles is of both theoretical and practical interest [1-3]. 
In this work, we curried out interaction of 2,5-dimethylbenzimidazole (
1
) with 
substituted arylsulfonyl chlorides. The aim of this work to study “
structure-biological 
activity
” relationship of the synthesized arylsulfonyl derivatives of benzimidazoles: 
Arylsulfonylation of 2,5-dimethylbenzimidazole (
1
) with substituted arylsulfonyl 
chlorides curried out in the presence of triethylamine at room temperature for 4 hours. 
As results we have synthesized corresponding N
1
-arylsulfonyl-2,5-dimethyl-
benzimidazoles (

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