2-8
) in good yields. The resulting products are potentially active
compounds.
The structure of the obtained products (
2-8
) was confirmed by results of
1
H,
13
C
NMR spectroscopy and mass-spectrometry.
References
1.
Mariappan G., Hazarika R., Alam F., Karki R., Patangia U., Nath S..
Arab.
J.Chem.
, 2015, Vol. 8, Iss. 5, 715–719.
2.
Radha Y., Manjula A., Madhava R.B., Vittal R.B.
Indian J. Chem.
, 2011,
Vol.50B, 1762-1773.
3.
Mashkovskii, M.D. (2004),
Drugs
. 14th ed., Moscow: New wave, Vols.1-2, 540
p., 608p.
4.
Poster presentation
266
OBTAINING ACARICIDES BASED ON OBTAINING INDENE
FROM A SECONDARY PRODUCT PRODUCED IN NATURAL
GAS PROCESSING AND THEIR BIOLOGICAL ACTIVITY
F. Z. Burkhev
1
, Q. J. Rustamov
2
Gulistan State University, Laboratory "Experimental biology"
1
Republican Center for the fight against termites
2
Email:
farkhod_2020@mail.ru
Heavy pyrolysis oil, which is considered a secondary product in natural gas
processing, is a complex multi-component mixture, a number of works are
underway to process it.
Thermal processing (fractional processing) (T
boil
=181°C)
under 165-185°C temperature conditions enabled producing indene containing liquids.
During the studies, it was found that the mixture obtained contains complexes
composed of methyl and ethyl-containing derivatives of indene and aromatic
compounds that contained various radicals. The initial fraction of pyrolysis oil
containing indene was influenced by Na metal to form a sodium compound of indene.
The resulting compound was transformed into a sodium salt of indene–1 carbonic acid
in a toluene medium. Various etherification reactions were conducted to obtain ethers
based on the indene ring. Taking into account the use of ethers obtained on the basis of
indene as acaricides, the effect of the obtained preparation “Inden–1” on red spider mite
that cause serious damage to agricultural crops was studied at the Republican Center for
the fight against termites at the Institute of Zoology of the Academy of Sciences of the
Republic of Uzbekistan.
The analysis of the obtained values of the biological effectiveness of the
experimental and etalon preparations by the ratio of the preparation and solvent gave the
following result: to combat red spider mites, 2ml of the A1 preparation was added to
100 ml of water and treated a certain number of insects. The calculations showed that on
day 3 after the exposure to the preparation, the effectiveness was 48.2%, 54.1% - after 7
days and 72.3% - after 14 days. At the same time, the insects were treated by adding 2
ml of the drug B1 to 20 ml of water. The calculations showed that the results were
46.2% on day 3 of the experiment, 80.6% on day 7, and on day 14 - 95.2%. The insects
were treated with the B1 preparation at 2 ml of it to 100 ml water ratio; from the
calculations point ov view, the values of biological efficiency in 3 days was 45.7%, on
day 7 of the experiment - 54.7% and in 14 days = 72.9%. For the purposes of
identifying the limits of affecting, the efficiency at adding 2 ml of B1 preparation to 500
ml water in 3 days was 22.2%, in 7 days - 32.3% and on day 14 - 51.8%.Then treatment
was conducted by adding 5 ml of C1 preparation to 500 ml water. In 3 days the 21.6%,
on day 7 - 32.4%, and in 14 days - 51.0% efficiency was registered.
We used 1.8% Abamectin solution as a reference substance. We prepared a standard
sample by adding 8 ml of the solution to 500 ml water. Treatment with the standard
sample showed that on day 3 od the experiment the efficiency value was 44.85, on day
7 - 81.4% and on day 14 of observations - 95.2%.
It was demonstrated that the highest efficiency value was achieved at the experiment
when 2 ml of the preparation was resolved in 20 ml water to use against red spider
Poster presentation
267
mites. It was identified that using this preparation for agricultural crop fileds would
meet the admitted criteria.
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