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3.6 Vitamin D
Obese pregnant women are more likely to be deficient in vitamin D than women of normal
weight, as obesity reduces the bioavailability of this vitamin. Fatty tissues require vitamin D
(which is fat-‐soluble) and make use of the maternal reserves; the greater the fatty tissue mass
of the mother, the more vitamin D she requires. Expectant mothers are often advised to take
additional vitamin D during pregnancy, especially in the Northern hemisphere, as sufficient
maternal vitamin D is required for the development of the fetal skeletomuscular system, brain
and immune system. Vitamin D deficiency may have a negative effect on the development of
the child’s bone tissue and cause long-‐term skeletal disorders, such as osteoporosis,
irrespective of the postnatal nutrition of the child. Vitamin D deficiency also increases the risks
for fetal growth impairment, low birth weight, neonatal tetanus, hypokalaemia, cardiovascular
disease and diabetes mellitus type I and incurs a lifelong risk for cancer. For the mother, vitamin
D deficiency is associated with risks for pre-‐eclampsia, premature delivery, insulin resistance,
gestational diabetes, dysfunction of the immune system and bacterial vaginosis.
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