Name : Manish Group : 5 1. Regulatory documents on immunoprophylaxis. Immunological mechanisms of action of vaccines. Characteristics of different types of vaccines. Organization of vaccination work. Indications and contraindications to vaccination. Ans. IMMUNOPROPHYLAXIS : . Immunoprophylaxis against viral illnesses includes the use of vaccines or antibody-containing preparations to provide a susceptible individual with immunologic protection against a specific disease. Immunization against viral illnesses can be either active or passive.
Mechanisms of action of vaccines. The immune system is a network of cells, tissues and organs that work together to help fight off infection from harmful bacteria or viruses. When a disease-causing agent, such as virus or bacteria, invades your body, your immune system recognises it as harmful and will trigger a response to destroy it. One of the ways your immune system fights off infection is by creating large proteins known as antibodies. These antibodies act as scouts, hunting down the infectious agent, and marking it for destruction by the immune system. Each antibody is specific to the bacteria or virus that it has detected and will trigger a specific immune response. These specific antibodies will remain in the immune system after the infection has gone. This means that if the same disease is encountered again, your immune system has a ‘memory’ of the disease and is ready to quickly destroy it before you get sick and any symptoms can develop.
Sometimes, however, the immune system doesn’t always win this initial battle against the harmful bacteria or virus and you can become very ill or – in extreme cases – die. Vaccination is the safest and most common way to gain immunity against a bacteria or virus that your body has yet to encounter. Vaccines contain a harmless form of the bacteria or virus that causes the disease you are being immunised against. The bacteria or virus will be killed, greatly weakened, or broken down into small parts before use in the vaccine so that they can trigger an immune response without making you sick. Your immune system will still attack the harmless form of bacteria or virus from the vaccine and will produce antibodies to fight it off. The immune system then keeps a memory of the disease, so if a vaccinated person encounters the disease years later, their immune system is ready to fight it off and prevent an infection from developing. VACCINATION TYPES Vaccine Management :