D. A. Bernlohr.
Univ. of Minnesota-Twin Cities.
3:40
Role of lipid peroxidation in cardiovascular health
and disease.
V. Darley-Usmar. Univ. of Alabama at
Birmingham.
4:05 Trans-4-hydroxy-2-hexenal, a product of n-3
polyunsaturated fatty acid peroxidation: make some
room, HNE.
M. J. Picklo, Sr. USDA, Grand Forks.
4:30 Impact of dietary n3 PUFAs on mitochondrial
phospholipids and function in heart.
W. C. Stanley.
Univ. of Maryland Baltimore.
4:55
PUFAs, mitochondrial ROS and Nrf2 in the heart: from
experimental models to the clinic.
E. Anderson. East
Carolina Univ.
179. MONAMINERGIC CONTROL OF BREATHING
DURING DEVELOPMENT
Symposium
(Sponsored by: APS Respiration Section)
s
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pm
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: K. J. C
umminGs
anD
m. r. h
oDGes
Physiology of Development
3:15
Acute loss of serotonin compromises gasping and
autoresuscitation in neonatal rats.
K. Cummings.
Univ. of Missouri-Columbia.
3:45
The role of serotonin in respiratory control during
development: rodent knockout.
M. Hodges. Med. Col.
of Wisconsin.
4:15
What do we know about the critical period of respiratory
development in the rat?
M. Wong-Riley. Med. Col. of
Wisconsin.
4:45
Monoamines, disturbances and respiratory rhythm.
J-C.
Viemari. CNRS-Aix Marseille Univ.
Please Silence Your Cell Phones during Sessions
SUNDAY PHYSIOLOGY
50
180. NEURONAL MEMBRANE/LIPID RAFTS:
ORGANIZERS OF MEMBRANE SIGNALING,
NEURITIC GROWTH AND GUIDANCE
Symposium
(Sponsored by: APS Central Nervous System Section)
s
un
. 3:15
pm
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C
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: B. p. h
eaD
anD
D. C
ooper
Central Control of Homeostasis
3:15
Neuron-targeted caveolin-1 enhances signaling and
promotes neuronal growth.
B. P. Head. UCSD, VA
Hosp.
3:45
Adenylyl cyclase and cyclic AMP compartmentalization.
D. Cooper. Univ. of Cambridge.
4:15 Calcium signaling and cellular excitability.
P. G.
Mermelstein. Univ. of Minnesota.
4:45
Monitoring reactive oxygen species in synaptosomal
lipid rafts.
S. S. Ali. Zewail City of Sci. and Technol.,
Egypt.
181. PARACRINE REGULATION OF RENAL TUBULE
FUNCTION
Symposium
(Sponsored by: APS Renal Section)
s
un
. 3:15
pm
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, 208
C
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: G. G
ieBisCh
anD
m. C
aplan
Transporters and Ion Channels
3:15
ATP release and signaling in renal epithelia.
H. A.
Praetorius. Aarhus Univ., Denmark.
3:45
Effects of luminal angiotensin on tubular function.
L. G.
Navar. Tulane Univ. Sch. of Med.
4:15
Regulation of distal tubule transport by kallikrein.
R.
Chambrey. INSERM U872, Paris.
4:45
Bicarbonate as a signaling molecule.
S. Wall. Emory
Univ. Sch. of Med.
182. PHYSIOLOGY AND PATHOLOGY OF CHLORIDE
TRANSPORTERS IN CNS
Symposium
(Sponsored by: APS Cell and Molecular Physiology
Section)
s
un
. 3:15
pm
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: F. J. a
lvarez
-l
eeFmans
anD
e. D
elpire
3:15 Functional roles of cation-coupled chloride
cotransporters (CCCs) in the CNS: an overview.
E.
Delpire. Vanderbilt Univ.
3:45
Molecular physiology of CSF potassium regulation by
CCCs expressed in choroid plexus epithelial cells.
F.
J. Alvarez-Leefmans. Wright State Univ.
4:15
CCCs in blood-brain barrier function and dysfunction.
M.
O’Donnell. Univ. of California, Davis.
4:45
CCCs in the genesis of seizure activity and epilepsy.
K. Staley. Harvard Med. Sch., Massachusetts Gen.
Hosp.
183. VASCULAR COGNITIVE IMPAIRMENT:
EMERGING CONCEPTS AND
PATHOPHYSIOLOGY
Featured Topic
(Sponsored by: APS Cardiovascular Section)
s
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. 3:15
pm
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: a. C
siszar
anD
J. p. W
arrinGton
Hypoxia and Oxidative Stress
Translational Physiology
3:15
Aging, hypertension and the genesis of vascular
cognitive impairment.
Z. Ungvari. Univ of Oklahoma
Hlth. Sci. Ctr.
3:45
Dysregulation of cerebral blood flow: new horizons.
D.
W. Busija. Tulane Univ. Sch. of Med.
4:15
Angiotensin-II hypertension aggravates neurovascular
dysfunction in mouse models of Alzheimer’s disease.
C. Iadecola, G. Faraco, A.M. Yebenes, L. Park and
G. Wang. Weill Cornell Med. Col. (709.12)
4:30
Novel roles for IGF-1 in cerebrovascular and brain
aging.
W.E. Sonntag. Univ. of Oklahoma, Oklahoma
City.
(709.9)
4:45 Blood-brain barrier leak precedes brain
histopathology and cognitive impairment in mild
hyperhomocysteinemia.
B.C. Rhodehouse, J.N.
Mayo, R.S. Beard, Jr., C-H. Chen and S.E. Bearden.
Idaho State Univ.
(709.11)
5:00
Aging exacerbates obesity-induced
cerebromicrovascular injury and cognitive decline in
mice.
Z. Tucsek, P. Toth, D. Sosnowska, T. Gautam,
W.E. Sonntag, Z. Ungvari and A. Csiszar. Univ. of
Oklahoma, Oklahoma City.
(709.10)
184. WEH NEW INVESTIGATOR AWARD LECTURE
(Sponsored by: APS Water and Electrolyte Homeostasis
Section)
s
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. 3:15
pm
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, 210a
Title: Exercise for the Treatment of Hypertension in
Pregnancy—Potential Mechanisms and Mediators
Speaker: J. S. Gilbert. Univ. of Oregon.
185. THE HENRY PICKERING BOWDITCH
MEMORIAL AWARD LECTURE
Lecture
s
un
. 5:45
pm
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, 210BC
Title: Translational Insights into the Regulation of
Coronary Blood Flow
Speaker:
J. D. Tune.
Indiana Univ. Sch. of Med.
PHYSIOLOGY SUNDAY
51
M
O
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MONDAY, APRIL 22
Across Societies – Experimental Biology
Critiquing of CV/Resumes is by appointment and starts at
9:30 AM on Sunday and continues until 5:00 PM on Wednesday.
Sign up on-site in the EB2013/FASEB Career Center, Hall B.
9:15
Goal setting, prioritizing, time management.
H. Adams.
9:15
NIH career development (K) award programs and early-
stage investigators.
H Khachaturian.
9:30
Economics and your job search.
J. Tringali.
9:30
Managing a lab.
S. Milgram, L. Conlan.
11:00 Compensation negotiation for scientists moving into
industry,.
B. Lindstaedt.
11:00
Sometimes it’s who you know: winning at networking.
J.
Blumenthal.
11:00
The academic job search in the life sciences: part 1.
A.
Green.
11:00 Developing your core message/elevator pitch.
J.
Lombardo.
11:00
The federal job hunt.
S. Milgram, L. Conlan.
1:00
The academic job search in the life sciences: part 2.
A.
Green.
1:00
Ten tough industrial interview questions: ten good
responses.
J. Tringali.
1:00
Making the case for graduate school.
H. Adams.
1:00
Managing up.
S. Milgram, L. Conlan.
1:30
Ten ways to get lucky in the job search.
P. Clifford, J.
Lombardo.
2:00
Careers in science education and outreach.
S. Milgram,
L. Conlan.
2:30
The job talk.
A. Green.
3:00
Job hunting in the biotech industry setting.
B. Lindstaedt.
3:00
Negotiation strategies for scientists.
D. Behrens.
3:00
Transforming your CV.
N. Saul.
3:00
Training at the NIH.
S. Milgram, L. Conlan.
4:00
Making the connection - resume, the interview and the
job.
J. Blumenthal.
186. NIH K AWARDS
Seminar
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B, C
areer
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: h. K
haChaturian
, niGms, nih
NIH Grants Seminar Workshop Series
Career Development
This presentation will focus on the NIH’s Career Development
Awards (K) including the most recent K99/00 Pathways to
Independence Award (for postdoctoral scientists) and other K
awards targeted to individuals with research doctoral degrees
(Ph.D. and equivalent) and clinical doctoral degrees (M.D. and
equivalent). Among the K awards discussed will be the K01
Mentored Research Scientist Development Award, the K02
Independent Scientist Award, the K22 Career Transition Award,
the K08 Mentored Clinical Scientist Development Award, the K23
Mentored Patient Oriented Career Development Award, the K24
Mid-Career patient Oriented Career Award, and K25 Mentored
Quantitative Scientist Career Development Award. The interactive
discussion will give attendees an opportunity to ask questions of
and obtain insight from an NIH representative on these and other
awards available for beginning investigators.
187. CAREER DEVELOPMENT SEMINARS AND
WORKSHOPS
Workshop
m
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. 9:00
am
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h
all
B, C
areer
C
enter
a
rea
Career Development
The following Seminars and Workshops will be held in the
EB2013/FASEB Career Center. There is no fee or pre-registration
associated with the workshops and seminars; just walk in and sit
down!
52
Anatomy
188. ANATOMICAL SCIENCES EDUCATION: THE
FUTURE
Plenary
m
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. 8:00
am
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, 104aB
C
oChaired
: r. D
raKe
anD
W. p
aWlina
Education & Teaching
Professional Development
8:00
188.1
Anatomy as a garden of educational delights:
medical education, professional formation, and the hidden
curriculum.
F.W. Hafferty. Mayo Clin.
9:00
188.2
Longitudinal integrated clerkship training as
a model for basic science education.
D. Hirsh. Harvard Med.
Sch.
189. PALEONTOLOGY AND FUNCTIONAL ANATOMY
Plenary
m
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. 10:30
am
—B
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, 104aB
C
oChaired
: J. l
aitman
anD
J. o
rGan
10:30
Joseph Leidy would be very proud: 125 years
of progress in paleontology and functional anatomy.
J. Laitman.
Mount Sinai Sch. of Med.
10:50
189.1
The Visible Interactive Dinosaur project:
fleshing out dinosaur head anatomy and function with advanced
3D imaging.
L.M. Witmer. Ohio Univ. Col. of Osteo. Med.
11:20
189.2
The evolution of human anatomy and
locomotion.
C.V. Ward. Univ. of Missouri-Columbia.
11:50
189.3
Integrative experimental approaches to
adaptive interpretations of the fossil record.
M.J. Ravosa. Univ.
of Notre Dame.
12:20 Discussion.
190. DEVELOPMENT AND REPROGRAMMING OF
VASCULAR SMOOTH MUSCLE
Symposium
m
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. 2:30
pm
—B
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C
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, 102aB
C
haired
: C. l
ittle
Developmental Biology
Cardiovascular
2:30
190.1
Development and diversity of vascular smooth
muscle progenitors.
M.W. Majesky. Univ. of Washington.
3:00
190.2
Vascular extracellular matrix and aortic cell
differentiation.
R. Mecham. Washington Univ. Sch. of Med.
3:30
190.3
Reprogramming of vascular smooth muscle
cells into calcifying cells: what can we learn from the embryo?
H. Kempf. INSERM, Vandoeuvre-les-Nancy.
191. REFRESHER COURSE: HISTOLOGY
TEACHING — PAST, PRESENT AND FUTURE
Symposium
(Supported by an educational grant from MBF Bioscience)
m
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. 2:30
pm
—B
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C
onvention
& e
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, 104aB
C
oChaired
: r. o
Gilvie
anD
r. m
C
C
usKey
Education & Teaching
2:30
Chair’s introduction.
2:35
191.1
The history of medical histology teaching:
where have we come from and where are we going?
R.A.
Bloodgood. Univ. of Virginia Sch. of Med.
3:00
191.2
Teaching histology in integrated curricula:
challenges and opportunities.
H. Amerongen. Univ. of Arizona.
3:25
191.3
A modern distributed learning histology course
with virtual lectures and labs.
R. Ogilvie and R. Sawyer. Univ.
of South Carolina and Med. Univ. of South Carolina.
3:50
Discussion.
192. COMPARATIVE PERSPECTIVES ON THE
HUMAN FACE: BIOMEDICAL IMPLICATIONS OF
EVOLUTIONARY ANATOMICAL RESEARCH
Symposium
(Cosponsored by: The Anatomical Record)
m
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. 2:30
pm
—B
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C
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, 104C
C
haired
: a. B
urroWs
2:30
Chair’s introduction.
2:35
192.1
Comparative anatomy of mammalian and
primate facial muscles and evolutionary genetics of atavistic
muscles in humans with trisomy.
J. Ziermann, R. Diogo and
N. Bhatia. Howard Univ.
3:00
192.2
Neuroanatomical causes and social
consequences of variation in facial motor control: what
comparative primatology can teach us about autism spectrum
disorders.
S. Dobson. Dartmouth Col.
3:25
192.3
How good are mice and monkeys as models
for human face transplants? Comparative physiological
perspectives on myosin fiber types.
A.M. Burrows, E.L.
Durham, L.C. Matthews, T.D. Smith and L.A. Parr. Duquesne
Univ., Univ. of Pittsburgh, Slippery Rock Univ., Emory Univ. and
Yerkes Natl. Primate Res. Ctr., Atlanta.
3:50
Discussion.
ANATOMY MONDAY
53
M
O
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193. TISSUE INJURY, STEM CELLS AND
REGENERATIVE MEDICINE
Platform
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pm
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unnWalD
Regeneration/Tissue Engineering
2:30
193.1
The Pitx2:miR-200 family axis regulates WNT
and BMP signaling during tooth morphogenesis and renewal.
X. Li, H. Cao, A. Jheon, Z. Sun, J. Wang, O. Klein and B.A.
Amendt. Univ. of Iowa and UCSF.
2:45
193.2
Osteogenic differentiation of mesenchymal
stem/stromal cells within 3D bioprinted neotissues.
A.J.
Evinger, J.M. Jeyakumar, L.A. Hook, Y. Choo, B.R. Shepherd
and S.C. Presnell. Organovo Inc., San Diego, Plasticell Ltd.,
London and Tissue Applications Gp., San Diego.
3:00
193.3
Sensory neurons accelerate reepithelialization
through substance P release in an innervated tissue-
engineered model of skin wound healing.
M. Blais, L. Mottier,
S. Cadau, R. Parenteau-Bareil and F. Berthod. Laval Univ.,
Canada.
3:15
193.4
Is salamander limb regeneration really
perfect? First detailed anatomical and morphogenetic analysis
of forelimb muscle regeneration in GFP-transgenic axolotls
as a basis for regenerative, developmental and evolutionary
studies.
R. Diogo and E. Tanaka. Howard Univ. and Ctr. for
Regen. Therapies, Dresden, Germany.
3:30
Breast milk is a novel source of stem cells
with multi-lineage differentiation potential.
F. Hassiotou, L.
Filgueira and P.E. Hartmann. Univ. of Western Australia and
Univ. of Fribourg, Switzerland.
(21.2)
3:45
193.5
Intrinsic pluripotent stem cells, Muse cells, are
a primary source of iPS cells in human fibroblasts.
M. Dezawa.
Tohoku Univ., Japan.
194. AAA KEYNOTE LECTURE
(Supported by an educational grant from AACBNC)
m
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. 4:30
pm
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, 104aB
4:30
194.1
Evo-devo and an expanding evolutionary
synthesis.
S.B. Carroll. , Bethesda.
195. AAA BUSINESS MEETING
m
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. 5:45
pm
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, 104aB
196. AAA STUDENT/POSTDOCTORAL POSTER
RECEPTION
Special Function
m
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. 6:30
pm
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