K.H. Patel and
D. Golemi-Kotra. York Univ., Canada.
C359
831.8
Prolactin receptors and signal pathways in the
rat prostate following the increase of systemic prolactin.
M.E.
Hernandez, L.I. Pascual, S. Rodriguez, G.E. Aranda-Abreu
and J. Manzo. Univ. Veracruzana, Mexico.
C360
831.9
ARHGEF3.2 modulates Wnt-PCP signaling
in dorsal marginal zone of Xenopus embryos during early
development.
J. Yoon, J-I. Heo, S.C. Kim, J-B. Park, J-Y. Lee
and J. Kim. Hallym Univ., South Korea.
C361
831.10 Study of Ras catalytic mechanism of intrinsic
hydrolysis of GTP.
R. Knihtila, G. Holzapfel and C. Mattos.
Northeastern Univ. and North Carolina State Univ.
C362
831.11 Insight into the involvement of G
bg in nuclear
G protein-coupled receptor signaling.
B.D. Spiegelberg, A.
Cymerman, L. Ripley and B. Enalls. Rider Univ., NJ.
C363
831.12 Macrophage destruction and loss of
immunoregulatory function contributes to the pathology
associated with MRSA pneumonia.
K. Kitur, D. Ahn, D. Parker
and A. Prince. Columbia Univ.
C364
831.13 c-Jun N-terminal kinase 1 is required for
coordination of netrin signaling in axon guidance.
C. Qu, W. Li,
Q. Shao, T. Dwyer, K-l. Guan and G. Liu. Univ. of Toledo, Univ.
of Michigan and UCSD.
C365
831.14 Effects of dextromethorphan mediated bitter
taste receptor activation in pulmonary artery smooth muscle
cells.
J.D. Upadhyaya, N. Singh, A.S. Sikarwar, R.P. Bhullar,
S. Dakshinamurti and P. Chelikani. Univ. of Manitoba.
C366
831.15 Identification of a cell adhesion molecule
involved in negative regulation of presynaptic assembly in C.
elegans.
H. Taru. Hokkaido Univ., Japan.
C367
831.16 Lysophosphatidic acid-mediated phosphor-
ylation of protein kinase D2 is dependent on PKC delta.
C.M.
Lynch and R.W. Matheny. U.S. Army Res. Inst. of Envrn. Med.,
Natick, MA.
Visit The Exhibits
Sunday–Tuesday
9:00 AM–4:00 PM
MONDAY BIOCHEMISTRY
254
C368
831.17 Study of the effect of Ca(OAc)
2
concentration
on the state of the allosteric switch in Ras GTPase.
C.W.
Johnson, K. Davis and C. Mattos. Northeastern Univ. and
North Carolina State Univ.
C369
831.18 The involvement of prohibition in Akt and Raf
co-regulated apoptosis of HaCaT keratinocytes upon UVB
irradiation.
Q. Wu and S. Wu. Ohio Univ.
C370
831.19 The differential effects of carnosol in regulation
of HaCaT cell apoptosis upon high or low dose of UVB
irradiation.
L. Tong and S. Wu. Ohio Univ.
C371
831.20 ERK MAP kinases are critical for the expression
of MKP-1 and MKP-2 in macrophages following LPS stimulation.
Y. Liu, J. Xue, Y. Shakibi, P. Xu, L.M. Wancket, L.D. Nelin and
W.J. Frazier. Nationwide Children’s Hosp. and The Ohio State
Univ. Col. of Med. and Col. of Vet. Med.
C372
831.21 Caveolin-1 is a critical determinant of
autophagy and oxidative stress.
N. Romero, T. Shiroto, H.
Kalwa, J. Sartoretto, T. Sugiyama and T. Michel. Brigham
and Women’s Hosp., Harvard Med. Sch.
832. MECHANISMS OF CELL GROWTH AND
AUTOPHAGY REGULATION
Poster
m
on
. 7:30
am
—B
oston
C
onvention
& e
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C
enter
,
e
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h
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a-B
Presentation time: 1:05
pm
-2:35
pm
C373
832.1
A tumor suppressor complex withGAP activity
for the Rag GTPases that signal amino acid sufficiency to
mTORC1.
L. Bar-Peled, L. Chantranupong, A. Cherniack,
W. Chen, K. Ottina, B. Grabiner, E. Spear, S. Carter, M.
Meyerson and D.M. Sabatini. Whitehead Inst. for Biomed.
Res., Broad Inst. of Harvard and MIT, John Hopkins Med. Sch.,
Dana-Farber Cancer Inst. and HHMI, Cambridge, MA.
C374
832.2
The NAADP/TC2/Ca
2+
signaling antagonizes
autophagosome maturation.
Y. Lu and J. Yue. The Univ. of
Hong Kong.
C375
832.3
Control of mitochondria destiny by autophagy
and a novel mitochondrial dynamics.
X-M. Yin and W-X. Ding.
Indiana Univ. Sch. of Med. and Univ. of Kansas Med. Ctr.
C376
832.4
The VMP1-beclin 1 interaction regulates
autophagy induction.
M.I. Molejon, A. Ropolo, G. Duette, M.
Santillan, V. Boggio and M.I. Vaccaro. Sch. of Pharm. and
Biochem., Univ. of Buenos Aires and CONICET, Buenos Aires.
C377
832.5
Potential SET protein involvement in autophagy
in cancer.
A.T. Ouchida, V.T. Uyemura, A.M. Leopoldino and
C. Curti. Univ. of São Paulo, Ribeirão Preto.
833. AGING
Poster
m
on
. 7:30
am
—B
oston
C
onvention
& e
xhiBition
C
enter
,
e
xhiBit
h
alls
a-B
Presentation time: 1:05
pm
-2:35
pm
C378
833.1
Accelerated chronologic aging of S.
cerevisiae induced by PUFA is associated to mitochondrial
dysfunction, enhanced sensitivity to lipid peroxidation and ROS
overproduction.
C. Cortes-Rojo, M. Fernández-Quintero, R.
Aguilar-Toral, K.A. Ballesteros-Coria, R. Montoya-Perez,
R. Mejia-Zepeda, A. Saavedra-Molina, J.L. Hernandez de la
Paz, M. Calderon and L.A. Madrigal-Perez. Univ. Michoacana
of San Nicolas de Hidalgo, Natl. Autonomous Univ. of Mexico,
Tlalnepantla and Higher Inst. of Tech. Ciudad Hidalgo, Mexico.
C379
833.2
Superoxide scavenging by natural antioxidants
studied using cyclic voltammetry.
C.C. Caldwell, M. Rossi, F.
Caruso and S. Belli. Vassar Col.
C380
833.3
Comparison of free radical scavenging abilities
of various chalcone antioxidants.
S. Lee, M. Rossi and F.
Caruso. Vassar Col.
C381
833.4
Exercise on a moving platform elicits different
gene expression of neurotrophins and receptors in the spinal
cord of aged rats.
N. Kanemura, H. Imagita, H. Maejima, T.
Kokubun, K. Murata and K. Takayanagi. Sch. of Hlth. and
Soc. Svcs., Saitama Prefect. Univ., Kio Univ. and Teikyo Univ. of
Sci., Japan.
834. APOPTOSIS AND CELL STRESS
Poster
m
on
. 7:30
am
—B
oston
C
onvention
& e
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C
enter
,
e
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h
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a-B
Presentation time: 1:05
pm
-2:35
pm
C382
834.1
Evidence that E2F1-mediated upregulation
of Bim, a proapoptotic BH3-only protein, functions as a
prosurvival molecule in cancer.
D. Chandra, R. Gogada, J. Liu,
D. Zhang, S. Tang, C.M. Aldaz, D. Tang and N. Yadav. Roswell
Park Cancer Inst. and MD Anderson Cancer Ctr., Smithville.
C383
834.2
Extracts of sweet potato leaves protect
b cells
from oxidative stress-mediated injury.
C-Y. Lin, T-Y. Chiang,
P-J. Huang and P-J. Li. Asia Univ., Taiwan.
C384
834.3
The anticancer effect of cytotoxin 1 from Naja
atra Cantor venom is mediated by a lysosomal cell death
pathway involving lysosomal membrane permeabilization and
cathepsin B release.
T. Kong, W. Ming, Y. Qiu, Y. Liu and W.
Dong. Guangzhou Med. Univ., China.
C385
834.4
The effect of camptothecin on nuclear RanGTP
levels in HeLa cells.
A.M. Steinheiser and K.K. Resendes.
Westminster Col., PA.
C386
834.5
The isothiocyanate, sulforaphane, alters the
acidification of the vacuole to trigger yeast cell death.
M.D.
Murphy, D.W. Tucker, A. Wilcox, S.K. Thomas, D. Laprade
and N. Austriaco. Providence Col.
C387
834.6
The role of HSF1 in maintenance of
b-catenin
stability in breast cancer stem cells.
S-D. Chou and S.
Calderwood. Beth Israel Deaconess Med. Ctr., Harvard Med.
Sch.
C388
834.7
Calcium promotes oxidative stress and
metabolic dysfunction in lipotoxicity.
R.A. Egnatchik, A.K.
Leamy, D.A. Jacobson and J.D. Young. Vanderbilt Univ.
POSTER PRESENTERS:
UPLOAD YOUR POSTER
Where: E-Poster Counter, Sun. – Tue. Hall A; Wed. Hall C
Deadline: Tue., April 23, 5:00
pm
; Wed., April 24, 3:00
pm
Uploaded posters will be available online to all
registered attendees following the meeting at
www. experimentalbiology.org
BIOCHEMISTRY MONDAY
255
M
O
N
C389
834.8
The role of PML in oxidative stress responses.
S. Guo, X. Cheng and H-Y. Kao. Case Western Reserve Univ.
and Salk Inst. for Biol. Studies.
C390
834.9
Elucidating the role of apoptosis during cyclical
body regeneration in Botryllus schlosseri.
M.A. Adamo and R.
Lauzon. Union Col., NY.
C391
834.10 Genome reduction in yeast involves
programmed cell death.
M.D. Hurton, E. Roblee, R.J. Bennett
and N. Austriaco. Providence Col. and Brown Univ.
C392
834.11 Small intestine and colon crypts differ in impact
of obesity, hyperinsulinemia and insulin-like growth factor
1 receptor loss on DNA damage-induced apoptosis.
M.A.
Santoro, R.E. Blue, L. Van Landeghem, K.K. McNaughton
and P.K. Lund. Univ. of North Carolina at Chapel Hill.
C393
834.12 Testicular macrophage activity correlates with
Leydig cell apoptosis following ethylene dimethane sulfonate
treatment of mature male Sprague-Dawley rats.
B. Singhal, S.
Gebrehiwot, S. Sang and N. Mills. Texas Woman’s Univ.
C394
834.13 VDAC phosphorylation impairment
causes mitochondrial membrane permeability during lipid
accumulation.
C. Martel, E. Fanelli, C. Boursier, C. Henry, G.
Calamita, A. Lemoine and C. Brenner. INSERM, Univ. Paris
Sud, Châtenay Malabry, State Univ. of Bari, Italy, PAPPSO,
INRA, Jouy-en-Josas and INSERM U1004/Paris XI, Hosp. Paul
Brousse, Villejuif.
C395
834.14 Changes in expression of multiple inositol
polyphosphate phosphatase1 under apoptotic and cellular
stress conditions.
S.P. Kilaparty and N. Ali. Univ. of Arkansas
at Little Rock.
C396
834.15 Development of a novel reporter system
to monitor ER stress.
J.Y. Moon, S.H. Back, J. Han and R.
Kaufman. Changwon Natl. Univ. and Univ. of Ulsan Sch. of
Biosci., South Korea and Sanford-Burnham Med. Inst., San
Diego.
C397
834.16 Assembly of apoptotic Bax oligomeric pore in
mitochondrial outer membrane requires relocation of helices
5, 6 and 9 from the monomer core to the lipid bilayer and/
or oligomer interfaces.
F. He, Z. Zhang and J. Lin. Univ. of
Oklahoma Hlth. Sci. Ctr.
C398
834.17 Biological impact of as-produced and purified
single wall carbon nanotube in kidney epithelial cells.
V.
Goornavar, S. Biradar, A.K. Pradhan and G.T. Ramesh.
Norfolk State Univ.
835. SIGNALING IN DISEASE AND THERAPY
Poster
m
on
. 7:30
am
—B
oston
C
onvention
& e
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C
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,
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a-B
Presentation time: 1:05
pm
-2:35
pm
C399
835.1
Constitutive HER2 signaling promotes breast
cancer metastasis through cellular senescence.
J. Arribas,
P.D. Angelini and M.Z. Fluck. Vall d’Hebron Inst. of Oncol.,
Barcelona.
C400
835.2
The selective growth inhibition of BRAF mutant
glioma cell lines by a new selective BRAF kinase inhibitor UI-
152.
N-Y. Kim, J-H. Ahn and M. Lee. Univ. of Incheon, South
Korea.
C401
835.3
Using chemical genetics to define zipper-
interacting protein kinase signaling events.
A.S. Al-Ghabkari,
C. Sutherland, M.P. Walsh and J.A. MacDonald. Univ. of
Calgary, Canada.
C402
835.4
Soluble ST2 controls allergic inflammation in
a murine model of asthma.
H. Hayakawa, M. Hayakawa, H.
Ohto-Ozaki and S-i. Tominaga. Jichi Med. Univ., Japan.
C403
835.5
Hyperglycemia induces an anti-angiogenic
milieu in first trimester cytotrophoblast cell.
M.N. Uddin, D.
Horvat, A.L. Roth, K.G. Pringle, S.R. Allen, R.O. Jones, D.C.
Zawieja and T.J. Kuehl. Scott & White Healthcare/Texas A&M
Hlth. Sci. Ctr. Col. of Med. and Univ. of Newcastle, Australia.
C404
835.6
Bcl-2 protein regulation of apoptosis in diabetic
cardiomyopathy.
K.M. Van Dalfsen and V. Del Gaizo Moore.
Elon Univ.
C405
835.7
Loss of Shp2 phosphatase favors alternative
activation of macrophages, contributing to pulmonary fibrosis
in mice.
B. Tao, X. Zhang, W. Jin, Y. Zhang, H.Q. Cheneg and
Y.H. Ke. Zhejiang Univ., China.
C406
835.8
HMG box-containing protein 1 as a downstream
signaling effector of EGFR in oral cancer.
C-Y. Chan, M-F.
Lee, S-Y. Huang, I-T. Chou, T-Y. Lin and C-Y. Huang. China
Med. Univ., Chang Jung Christian Univ. and Taipei Med. Univ.,
Taiwan.
C407
835.9
The Akt-mTOR axis determines cell fate
through the regulation of eIF2alpha phosphorylation
pathway.
A.E. Koromilas, C. Tenkerian, Z. Mounir and J.
Krishnamoorthy. McGill Univ., Lady Davis Inst. for Med. Res.,
Montreal and Novartis Inst. for Biomed. Res., Cambridge, MA.
C408
835.10 Interleukin-6 induces ErbBs receptor
phosphorylation and utrophin expression in dystrophic
myotubes.
N. Juretic, J. Díaz, E. Jaimovich and N. Riveros.
Fac. of Med., Univ. of Chile.
C409
835.11 Andrographolide activates the Wnt pathway
and modulates the APP processing by direct inhibiton of
GSK3
b. C.C. Tapia, C. Mejías, H. Bustamante, P. Burgos and
N.C. Inestrosa. Pontifical Catholic Univ. of Chile and Austral
Univ. of Chile.
C410
835.12 The mechanism by which the TfR2/HFE
complex affects iron homeostasis.
C.A. Worthen, M.
Chloupková, K. Noguchi and C.A. Enns. Oregon Hlth. & Sci.
Univ.
C411
835.13 Rapamycin attenuates cardiac expression of
anti-inflammatory AT2R and anti-apoptotic MCL1.
N. Arnold,
D. Somashekara, R. Gul, R. Speth and L. Pulakat. Univ. of
Missouri-Columbia, Harry S. Truman VA Hosp. and Col. of
Pharm., Nova Southeastern Univ.
C412
835.14 Hyperthermia-induced NDRG2 upregulation
inhibits the invasive potential of HepG2 cell via suppressing
ERK1/2 signaling pathway.
J. Zhang, Y. Guo, X. Li, J. Zhang,
W. Liu and L. Yao. Fourth Military Med. Univ. and Xijing Hosp.,
China.
C413
835.15 TGF-
b regulated miRNAs: therapeutic targets
for cardiac hypertrophy.
X. Yang and J. Wang. Beijing Inst. of
Biotechnol.
836. SIGNALING TO THE NUCLEUS
Poster
m
on
. 7:30
am
—B
oston
C
onvention
& e
xhiBition
C
enter
,
e
xhiBit
h
alls
a-B
Presentation time: 1:05
pm
-2:35
pm
C414
836.1
Pleiotropic effects of PI3K/Akt pathway in
hippocampal neurons exposed to iron-induced oxidative stress.
R.M. Uranga, N.M. Giusto and G.A. Salvador. Res. Inst. of
Biochem., Bahía Blanca-CONICET and Natl. Univ. del Sur,
Argentina.
MONDAY BIOCHEMISTRY
256
C415
836.2
Characterization of thyroid hormone receptor
export pathways.
H.N. Nelson and L.A. Allison. The Col. of
William and Mary.
837. TRANSCRIPTIONAL REGULATION AND
EPIGENETIC CONTROL
Poster
m
on
. 7:30
am
—B
oston
C
onvention
& e
xhiBition
C
enter
,
e
xhiBit
h
alls
a-B
Presentation time: 1:05
pm
-2:35
pm
C416
837.1
Cytosine DNA methylation influences drug
sensitivity through SugE expression in Escherichia coli.
A.H.
Mandarano, O. Varechtchouk, R.D. Simon and K.T. Militello.
SUNY at Geneseo.
C417
837.2
CTBP regulates the early SEC assembly prior
to onset of transcription elongation.
J.S. Byun and K. Gardner.
NCI, NIH.
C418
837.3
Maternal high fat diet programs gene expression
of adipogenic transcription factors through regulating histone
modifiers in a gender-dependent manner.
D. Zhou, H. Wang
and Y-X. Pan. Univ. of Illinois, Urbana.
C419
837.4
Maternal high-fat diet increases rat hepatic
interleukin-4 mRNA expression and is associated with
decreased DNA methylation in male offspring.
H. Wang, D.
Zhou, Y. Wang and Y-X. Pan. Univ. of Illinois, Urbana.
838. BMB EDUCATION AND PROFESSIONAL
DEVELOPMENT
Poster
m
on
. 7:30
am
—B
oston
C
onvention
& e
xhiBition
C
enter
,
e
xhiBit
h
alls
a-B
Presentation time: 12:25
pm
-1:55
pm
C420
838.1
STEP into Science at Medgar Evers College,
a successful strategic plan.
M.A. Carroll, D. Skeete and E.J.
Catapane. Medgar Evers Col., CUNY.
C421
838.2
The Pre-health Collection within
MedEdPORTAL’s iCollaborative: faculty resources to prepare
students for the MCAT2015.
H.V. Jakubowski and L.S.
Zapanta. Col. of Saint Benedict, St. John’s Univ., MN and Univ.
of Pittsburgh.
C422
838.3
Student conceptions and misconceptions
about energy transformations in biochemistry.
A.J. Wolfson,
S.L. Rowland, G.A. Lawrie and T.H. Wright. Wellesley Col.
and Univ. of Queensland, Australia.
C423
838.4
Essential concepts and underlying theories
from physics, chemistry, and mathematics for the molecular life
sciences.
A. Wright, E. Bell, J. Provost and J.A. Roecklein-
Canfield. Canisius Col., NY, Univ. of Richmond, Minnesota
State Univ. Moorhead and Simmons Col.
C424
838.5
A metabolic pathways diagnosis test for
assessing the development of biochemistry students’
visualization skills.
E. Galembeck, V.J.S.V. dos Santos and
T. Anderson. UNICAMP, Campinas, Brazil, Purdue Univ. and
Fed. Univ. of São João, Brazil.
C425
838.6
Incorporating biotechnology in the high school
classroom: professional development for biology teachers.
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