967.1
The chick embryo neural crest model system
reveals a unique role for EphB6 in melanoma metastasis.
C.M.
Bailey and P.M. Kulesa. Stowers Inst. for Med. Res., Kansas
City, MO.
A381
967.2
Empirical development of a histological protocol
for whole brain sectioning to characterize neuropathological
patterns in human specimens.
K.M. Chan, N.A. Schmalz, K.
Choy, A. Nguyen, T.N. Pham, E. Stark, H. Dong, A.W. Toga,
H.V. Vinters and J.J. Wisco. David Geffen Sch. of Med. at
UCLA and Brigham Young Univ.
A382
967.3
Quantitative co-localization of hyaluronic acid
and damaged myelin in the aging rhesus monkey brain.
L.I.
Estrada, P. Boule-Getsinger, E. Witkowski, F. Mortazavi and
D.L. Rosene. Boston Univ. Sch. of Med.
A383
967.4
Understanding craniofacial variability caused
by loss of Gata3 function.
J.K. Eberhart and M.E. Swartz.
Univ. of Texas at Austin.
A384
967.5
Characterization of the avian Talpid2 mutant.
S.A. Brugmann, C-F. Chang, E.N. Schock, J. Snyder and
M.E. Delany. Cincinnati Children’s Hosp. Med. Ctr. and Univ. of
California, Davis.
A385
967.6
Three-dimensional reconstructions of human
embryos: morphogenesis and hepatic vascularization.
M.
Lhuaire, E. Scharbarg, É. Micard, R. Cendre, V. Delmas, F.
Duparc, P. Mercier, J. Felblinger, M. Braun, C. Avisse and
M. Labrousse. Univ. of Reims Champagne-Ardenne, CHU de
Nancy Brabois, René Descartes Univ. Paris V, Rouen Univ.,
Angers Univ. and Henri Poincaré-Lorraine Univ., Nancy.
A386
967.7
C-jun N-terminal kinase maintains tissue
integrity during cell rearrangement in the gut.
N. Nascone-
Yoder and M. Dush. Col. of Vet. Med., North Carolina State
Univ.
LAST DAY TO VISIT
EXHIBITS
Tuesday, April 23
9:00 AM – 4:00 PM
ANATOMY TUESDAY
327
T
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A387
967.8
Syntaxin 16 is required for epithelial
morphogenesis and single lumen formation.
J-J. Jung, S.M.
Inamdar, A. Tiwari, D. Ye, F. Lin and A. Choudhury. Univ. of
Iowa.
A388
967.9
microRNA-26b represses colon cancer
cell proliferation by inhibiting lymphoid enhancer factor 1
expression.
Z. Sun, Z. Zhang, X. Li and B. Amendt. Univ. of
Iowa.
A389
967.10 Reducing parathyroid hormone is essential for
correcting cortical bone deficiencies associated with chronic
kidney disease.
C. Newman, S.M. Moe, N.X. Chen, D.M.
Brown, V.H. Gattone and M.R. Allen. Indiana Univ. Sch. of
Med.
Biochemistry and Molecular Biology
968. MECHANISMS OF GENOMIC STABILITY
Poster
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C1
968.1
Role of Ku in the DNA damage response
activated from telomeres.
V. Fell and C. Schild-Poulter. Univ.
of Western Ontario and Robarts Res. Inst., London, Canada.
C2
968.2
Activity and frequency of the ITPA P32T variant
among colorectal patients.
C. Brown. Wayne State Col.
C3
968.3
Chromosome fragile sites signature and
genome instability in human epithelial cells.
S.A. Hosseini, J.C.
Saldivar, S. Horton, J. Sun, N.A. Heerema and K. Huebner.
The Ohio State Univ. Wexner Med. Ctr.
C4
968.4
Coordinated degradation of replisome
components ensures genome stability upon replication stress.
E. Noguchi, L. Roseaurlin and T. Toda. Drexel Univ. Col. of
Med. and Cancer Res. UK, London.
C5
968.5
Effect of high copy retrotransposon insertions
on yeast genome stability.
C. Lanzillotta and L.Z. Scheifele.
Loyola Univ. Maryland.
969. CHROMATIN MODIFICATIONS AND
REMODELING IN DNA REPLICATION,
RECOMBINATION AND REPAIR
Poster
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. 7:30
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Presentation time: 12:25
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C6
969.1
Chromatin dynamics and the Fanconi anemia
DNA damage response pathway.
K.L. Neira, M. Mauro and
N.G. Howlett. Univ. of Rhode Island.
C7
969.2
DNA damage repaired by the base excision
repair pathway is epigenetic.
P.R. Strauss, K. Toomire and
S.P.G. Moore. Northeastern Univ.
C8
969.3
Dynamics of yeast histone H2A and H2B
phosphorylation in response to a double-strand break.
C-S.
Lee, K. Lee, J.E. Haber and G. Legube. Brandeis Univ.,
CNRS, Toulouse and Univ. of Toulouse.
C9
969.4
Nucleosome dynamics regulate DNA
processing.
N. Adkins, H. Niu, P. Sung and C. Peterson. Univ.
of Massachusetts Med. Sch. and Yale Univ. Sch. of Med.
C10
969.5
ATP-dependent heterochromatin remodeling.
B.J. Manning and C. Peterson. Grad. Sch. of Biomed. Sci.,
Univ. of Massachusetts Med. Sch.
C11
969.6
Role of salicylic acid in chromatin modification
and remodeling.
D. Kumar, M.I. Haq, T.A. Hotz, M.A. Hossain,
B. Zhao and D. Donald. East Tennessee State Univ.
C12
969.7
Transcription factor Sp1 promotes chromatin
remodeling at DNA double-strand breaks.
K. Beishline, S.
Koduri and J. Clifford. Drexel Univ. Col. of Med.
970. CHROMOSOME REARRANGEMENTS
Poster
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. 7:30
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Presentation time: 12:25
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C13
970.1
Analyzing the effects of sub-optimal doses
of raltegravir on HIV-1 integration.
J. Varadarajan, M.J.
McWilliams, D. Hazuda and S. Hughes. NCI, NIH, Frederick
and Merck Res. Labs., West Point, PA.
971. GENOME DIVERSITY AND DNA
RECOMBINATION
Poster
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. 7:30
am
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Presentation time: 12:25
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pm
C14
971.1
Large-scale structural variations linked to the
NOTCH4 locus of the human major histocompatibility complex.
J.D. Bowman, B. Zhou, C-y. Yu and S.K. Lawrance. Otterbein
Univ., OH and Nationwide Children’s Hosp.
C15
971.2
Determination of the extent of hybridization
between the threatened Hibiscus dasycalyx, Hibiscus laevis,
and Hibiscus moscheutos using ISSR genetic markers.
L.M.
Baker and B. Clack. Stephen F. Austin State univ.
972. MECHANISM OF DNA RECOMBINATION
Poster
t
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. 7:30
am
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Presentation time: 12:25
pm
-1:55
pm
C16
972.1
Isolation and characterization of isopentenyl-
diphosphate isomerase from marine bacterium, Kocuria
gwangalliensis.
T.H. Jeong, K. Ji, N.Y. Jang, Y.S. Cho and Y.T.
Kim. Pukyong Natl. Univ., South Korea.
TUESDAY ANATOMY/BIOCHEMISTRY
328
973. MECHANISM OF DNA RECOMBINATION
Poster
t
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. 7:30
am
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oston
C
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Presentation time: 12:25
pm
-1:55
pm
C17
973.1
Pch2 is a meiotic hexameric ATPase that binds
to and alters Hop1 functions.
C. Chen, A. Jomaa, J. Ortega
and E. Alani. Cornell Univ. and McMaster Univ., Canada.
C18
973.2
Molecular delineation of BubR1 kinase function
in kinetochore microtubule attachments.
H. Jiang, Y. Huang, X.
Ding and X. Yao. Anhui Key Lab. of Chem. Biol., Heifei, China,
Beijing Univ. of Chinese Med. and Morehouse Sch. of Med.
974. MUTAGENESIS
Poster
t
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. 7:30
am
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Presentation time: 12:25
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-1:55
pm
C19
974.1
ENU-induced mutagenesis in grass carp
(Ctenopharyngodon idellus) by treating mature sperm.
S-M.
Zou and X-Y. Jiang. Shanghai Ocean Univ.
C20
974.2
Evaluation of oxidative DNA damage, lipid
peroxidation and antioxidant status in patients undergoing
surgery with sevoflurane anesthesia.
M.G. Braz, J.E.B. Orosz,
D.T. Pierine, L.G. Braz, A.L.A. Ferreira, D.M.F. Salvadori,
K-J. Yeum and J.R.C. Braz. São Paulo State Univ., Botucatu
and USDA at Tufts Univ.
C21
974.3
Improvement of P. chrysogenum by UV
mutation for overproduction of cellulase and ligninase.
O.M.
Babalola, , M.O. Abiola, E.O. Albert, I.O. Ngozi and E.N.
Miriam. Univ. of Lagos, Nigeria.
C22
974.4
Monitoring the expression and activity of the
DinB protein in vivo in Escherichia coli.
B.H. Diamond and V.
Godoy-Carter. Northeastern Univ.
975. NUCLEIC ACID- SMALL MOLECULE
INTERACTIONS
Poster
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. 7:30
am
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Presentation time: 12:25
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pm
C23
975.1
Structural characterization of the major DNA-
DNA cross-link formed by epichlorohydrin.
K. Sirka and J.T.
Millard. Colby Col., ME.
C24
975.2
Mechanisms of cytotoxicity of bifunctional
epoxide cross-linking agents.
A. Spierer and J.T. Millard.
Colby Col., ME.
C25
975.3
Amplification of human DNA for probing DEB-
induced damage via a quantitative polymerase chain reaction.
E. Chuang and J.T. Millard. Colby Col., ME.
C26
975.4
The role of microRNA-208a in cardiac
hypertrophy induced by aerobic physical training.
U.P.R. Soci,
T. Fernandes, K.T. Rosa, M.C. Irigoyen, M.I. Phillips and
E.M. de Oliveira. Sch. of Phys. Educ. and Sports and INCOR-
FMUSP, São Paulo and Keck Grad. Inst., Claremont, CA.
C27
975.5
A novel series of antitumor ruthenium beta-
diketonato compounds.
J. Matthews, F. Caruso, C. Pettinari,
F. Marchetti, R. Pettinari, M. Cariboldi and M. Rossi. Vassar
Col. and Univ. of Camerino and Univ. of Insubria, Italy.
C28
975.6
Investigation of riboflavin binding to DNA using
polymerase chain reaction.
M. Banco and M.A. Benore. Univ.
of Michigan at Dearborn.
C29
975.7
A novel CUGexp·MBNL1 inhibitor with
therapeutic potential for myotonic dystrophy type 1.
A.H.
Jahromi and S.C. Zimmerman. Univ. of Illinois, Urbana.
C30
975.8
DNA-nuclear protein interactions around -224
A/G single nucleotide polymorphism in the neuropeptide
receptor Y2 (NPY2R) gene in predisposition to hypertension.
E.M. Albino-Rodriguez, T. Katsuya, A. Deng and J. Dutil.
Ponce Sch. of Med., PR, Osaka Univ. Grad. Sch. of Med. and
Univ. of Montreal Res. Ctr. CHUM.
976. TRANSLESION AND ERROR-PRONE DNA
POLYMERASES
Poster
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C31
976.1
Functional studies of point mutation G295R on
the catalytic core of human DNA polymerase
h. A.J. Valdez, M.
Kumar and X. Jiang. Tennessee Technol. Univ.
C32
976.2
Site-directed mutagenesis, expression,
purification and translesion synthesis analysis of human DNA
polymerase
h mutations found in xeroderma pigmentosum
variant and melanoma patients.
M. Kumar and X. Jiang.
Tennessee Technol. Univ.
C33
976.3
Werner’s syndrome protein limits the error-
prone 8-oxo-G lesion bypass activity of human DNA polymerase
kappa by promoting the error-free bypass.
L. Maddukuri, S.D.
Eddy and R.L. Eoff. Univ. of Arkansas for Med. Sci.
C34
976.4
Regulation of DNA damage tolerance by the
AhR pathway and its role in glioma progression.
A. Bostian
and R. Eoff. Univ. of Arkansas for Med. Sci.
C35
976.5
Overexpression of human polymerase
n in E.
coli.
S.C. Shissler and X. Jiang. Tennessee Technol. Univ.,
Oak Ridge and Cookeville.
C36
976.6
Replication of G-quadruplexes by archaeal
DNA polymerases.
S.D. Eddy, L. Maddukuri and R.L. Eoff.
Univ. of Arkansas for Med. Sci.
C37
976.7
Antibiotic resistance acquired through a DNA
damage-inducible response in Acinetobacter baumannii.
M.D.
Norton and V.G. Godoy. Northeastern Univ.
977. TRANSPOSITION
Poster
t
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. 7:30
am
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Presentation time: 12:25
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pm
C38
977.1
Cooperative role of MMP-3 and HP1 in heat
shock protein transcription.
T. Eguchi and S. Calderwood.
Beth Israel Deaconess Med. Ctr., Harvard Med. Sch.
BIOCHEMISTRY TUESDAY
329
T
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978. CHROMOSOMES
Poster
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Presentation time: 12:25
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pm
C39
978.1
HU decreases diffusible supercoiling density
in bacterial chromosome.
A.A. Agbleke, N. Rovinskiy,
O. Chesnokova and P.N. Higgins. Univ. of Alabama at
Birmingham.
C40
978.2
Cohesin-dependent association of tRNA
genes with nuclear pore complexes in budding yeast.
M. Chen
and M.R. Gartenberg. UMDNJ-Robert Wood Johnson Med.
Sch.
979. MITOTIC SPINDLE
Poster
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. 7:30
am
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Presentation time: 12:25
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pm
C41
979.1
Aurora-A-elicited astrin phosphorylation
regulates mitotic progression.
S-C. Chiu, J-M.M. Chen, M-C.
Liu and C-T.R. Yu. China Med. Univ., China Med. Univ. Hosp.
and Natl. Chi Nan Univ., Taiwan.
980. MECHANISMS OF GENE TRANSCRIPTION AND
REGULATION II
Poster
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. 7:30
am
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Presentation time: 1:05
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-2:35
pm
Session I scheduled on Monday.
C42
980.1
Function of CDK8 submodule and TRIM28
in transcriptional regulation at HSPA1B.
H. Bunch and S.
Calderwood. Beth Israel Deaconess Med. Ctr., Harvard Med.
Sch.
C43
980.2
The QA repeat domain of TCERG1 plays a role
in inhibiting C/EBP
a and in its ability to undergo redistribution
in the nucleus.
W.J. Roesler, N. Miller, N. Timchenko and B.
Moazed. Univ. of Saskatchewan and Baylor Col. of Med.
C44
980.3
Transcriptional regulator MftR from
Burkholderia thailandensis participates in oxidative stress
responses.
A. Gupta and A. Grove. LSU.
C45
980.4
Regulation of CFTR gene expression by
recruitment of an intestinal transcription factor network.
J.
Kerschner and A. Harris. Children’s Hosp. of Chicago Res.
Ctr. and Northwestern Univ. Feinberg Sch. of Med.
C46
980.5
Identify PCBP1-interacting protein and its
novel functional role on human MOR gene expression.
P.
Nahar-Gohad, H. Sultan, Y. Esteban, A. Stabile and J. Ko.
Seton Hall Univ.
C47
980.6
Effects of recognition sequence variations on
transcription regulation of multidrug resistance regulator Pdr1p
in yeast.
N. Nishida, K. Kuroda and M. Ueda. Kyoto Univ.
Grad. Sch. of Agr.
C48
980.7
Characterization of lysine-specific demethylase
1 as a potential olfactory receptor regulator.
A.L. Savarino, S.
Kilinc and R. Lane. Wesleyan Univ.
C49
980.8
Extra-transcriptional effects of RNA polymerase
III transcription complex on neighboring RNA polymerase II
transcribing genes in Saccharomyces cerevisiae.
A. Korde,
J.M. Rosselot and D. Donze. LSU.
C50
980.9
The Ure2
acap is required for GATA factor
responses to rapamycin, but not nitrogen limitation.
J.J. Tate,
A. Feller, I. Georis, E. Dubois and T.G. Cooper. Univ. of
Tennessee Hlth. Sci. Ctr., Memphis and Univ. Libre of Brussels.
C51
980.10 Study on the neurogenic mechanisms of
traumatic brain injury.
H. Duan, Y. Fan, C. Hao, S. Li, S. Wang,
H. Wang, D. Kuai, S. Lian and N. Xue. First Clin. Col. of Shanxi
Med. Univ., China.
981. EPIGENETICS: HISTONE AND DNA
MODIFICATIONS
Poster
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. 7:30
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Presentation time: 1:05
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-2:35
pm
C52
981.1
The role of neuropeptide Y and aquaporin 4 in
the pathogenesis of intestinal dysfunction caused by traumatic
brain injury.
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