H. Duan, C. Hao, S. Li, Y. Fan, H. Wang, J. Hao, Y.
Liu and X. Liu. The First Clin. Col. of Shanxi Med. Univ., China.
C53
981.2
MeCP2_e2 does not contribute Rett syndrome
phenotypes but essential for placenta.
M. Itoh, C.G.T. Tahimic,
Y-i. Goto and A. Kurimasa. Natl. Ctr. of Neurol. and Psychiat.,
Kodaira and Tottori Univ., Japan.
C54
981.3
Epigenetic markers in patients with
endometriosis.
K.L. Ray, M. Isme, C. Cook, M. Massie, B.
Dawley and N. Santanam. Marshall Univ. and Bluefield State
Col., WV.
C55
981.4
Epigenetic changes in human cells exposed
to X-rays.
M.A. Chaudhry and R.A. Omaruddin. Univ. of
Vermont.
C56
981.5
IGF1 growth hormone response element
undergoes developmentally regulated demethylation
independent of STA5b.
R.A. McKnight, J. Wiedmeier, X. Yu,
C.W. Callaway and R.H. Lane. Univ. of Utah.
C57
981.6
High fat diet induced genome-wide differential
methylation affecting hepatic signaling pathways in rat.
Y.
Zhang, D. Zhou, J. Ma, Y-X. Pan and H. Chen. Univ. of Illinois
at Urbana-Champaign.
C58
981.7
The detection of 5-hydroxymethylcytosine in
Trypanosoma brucei DNA.
E. Valentine, R. Smindak and K.T.
Militello. SUNY at Geneseo.
C59
981.8
Replication and transcription of SV40 direct
distinct epigenetic signaling.
B. Milavetz, L. Kallestad, A.
Gefroh, E. Woods and K. Christensen. Univ. of North Dakota.
C60
981.9
Regulation of the DNA-binding protein CFP1
by ERK1/2.
A.M. Klein, S. Earnest and M.H. Cobb. Univ. of
Texas Southwestern Med. Ctr.
TUESDAY BIOCHEMISTRY
330
982. HETEROCHROMATIN
Poster
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Presentation time: 1:05
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pm
C61
982.1
Sirtuins mediate cohesion of silenced domains
in Saccharomyces cerevisiae.
Y-F. Chen and M. Gartenberg.
UMDNJ-Robert Wood Johnson Sch. of Med.
983. NON-CODING RNAS IN GENE REGULATION
AND CHROMOSOME STRUCTURE
Poster
t
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. 7:30
am
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C
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Presentation time: 1:05
pm
-2:35
pm
C62
983.1
Identification of SCAL1, a novel long non-
coding RNA, induced by cigarette smoke and associated with
lung cancer.
P. Thai, S. Statt, E. Liang, C. Campbell and R.
Wu. Univ. of California, Davis.
984. RECOMBINANT DNA TECHNOLOGY
Poster
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. 7:30
am
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Presentation time: 1:05
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-2:35
pm
C63
984.1
A biologist’s resource for protein expression
plasmids: the Protein Structure Initiative:Biology-Materials
Repository.
C. Cormier, J. Park, M. Fiacco, J. Steel, P. Hunter
and J. LaBaer. Biodesign Inst., Arizona State Univ.
C64
984.2
Vaccination of BALB/c mice against a murine
hookworm model.
M.W. Schlotterback, P. Comella, C. Horien,
K. Neutzling, K. Luk, E. Richards and J. Pearson. Concordia
Col., MN.
C65
984.3
Innovative immunological assays for diagnosis
of Schistosoma mansoni for clinical acute and/or chronic forms.
R.F.G. Queiroz, D. Harn and P.M. Coelho. Fiocruz, Belo
Horizonte, Brazil and Univ. of Georgia.
C66
984.4
Large-scale expression and purification of
active pseudolysin in Escherichia coli.
R.S. Tarpley, O.A.
Adekoya, I. Sylte and O.O. Odunuga. Stephen F. Austin State
Univ., TX and Univ. of Tromsø, Norway.
C67
984.5
Novel method for the scarless single-step
assembly of many small DNA sequences.
T.L. Roth, L.
Milenkovic and M. Scott. Stanford Univ.
C68
984.6
Synthetic biology and the production from
Brazilian spider silk protein Masp1 in E. coli system.
V.A.
Michalczechen-Lacerda, P.F. Oliveira, G.R. Vianna, A.M.
Murad, D.L. Kaplan and E. Rech. Tufts Univ. and Univ. of
Brasilia.
985. FRONTIERS IN RNA BIOLOGY
Poster
t
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. 7:30
am
—B
oston
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onvention
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Presentation time: 1:05
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-2:35
pm
C69
985.1
Inhibition of HIV-1 transcription by a tunable
chimeric tRNA(Ser)-nucloelar localizing trans-activation
response element decoy.
C. Stevens, L. Scherer, J. Rossi and
K. Haushalter. Harvey Mudd Col., CAand Beckman Res. Inst.,
Duarte, CA.
986. RIBOSOME AND TRANSLATION
Poster
t
ue
. 7:30
am
—B
oston
C
onvention
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Presentation time: 1:05
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-2:35
pm
C70
986.1
The disassembly of post-termination complex
by ribosome recycling factor and EF-G occurs first with the
releases of tRNA, mRNA, and splitting of the ribosome in its
order – IF3 does not participate in this reaction.
A. Kaji, N.
Iwakura and H. Kaji. Univ. of Pennsylvania Sch. of Med. and
Thomas Jefferson Univ. Kimmel Cancer Ctr.
C71
986.2
Actin bundling mutants in translation elongation
factor 1A induce altered protein synthesis at both the initiation
and elongation steps.
W.B. Perez and T.G. Kinzy. UMDNJ-
Robert Wood Johnson Med. Sch.
C72
986.3
Cloning and characterization of leucyl-tRNA
synthetase from Pseudomonas aeruginosa.
E. Medellin, H.
Salazar, N. Quach, P. Chavero and J. Bullard. Univ. of Texas
-Pan American.
C73
986.4
Enzymatic analysis of EF-Tu and EF-Ts from
Pseudomonas aeruginosa.
A. Tran, S. Palmer and J. Bullard.
Univ. of Texas-PA.
C74
986.5
Cloning and characterization of EF-Tu and EF-
Ts from Bacillus subtilis.
C. Rivera, V. Garcia and J. Bullard.
Univ. of Texas-PA.
C75
986.6
Evolution of ribosomal RNA: universal and
domain-specific conserved sequences.
S.A. Gerbi, S.M. Doris,
D. Smith, B. Raphael, J. Beamesderfer and J. Nathanson.
Brown Univ.
C76
986.7
Widespread regulation of translation by
elongation pausing in heat shock.
R. Shalgi, S. Lindquist and
C.B. Burge. MIT and Whitehead Inst. for Biomed. Res.
C77
986.8
Primary and alternative S18 ribosomal protein
in Mycobacterium tuberculosis.
S. Prisic and R.N. Husson.
Boston Children’s Hosp./Harvard Med. Sch.
987. RNA EDITING AND MODIFICATION
Poster
t
ue
. 7:30
am
—B
oston
C
onvention
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Presentation time: 1:05
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-2:35
pm
C78
987.1
Characterization of putative mitochondrial
processing peptidase
a-subunit in Trypanosoma brucei. I.L.
Mak, Z. Lu, V.N. Mehta and R. Salavati. McGill Univ.
BIOCHEMISTRY TUESDAY
331
T
U
E
988. RNA PROCESSING
Poster
t
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. 7:30
am
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Presentation time: 1:05
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-2:35
pm
C79
988.1
Structural insights into RNase T in RNA
maturation and DNA repair.
H.S. Yuan, Y-Y. Hsiao and W-C.
Chu. Inst. of Molec. Biol., Acad. Sinica, Taipei and Natl. Yang-
Ming Univ., Taiwan.
C80
988.2
Investigation of functionally critical residues
in the pseudo-helicase domain of Brr2.
D. Anguiano, C.M.
Brittsan, J.K. Titus, W. Boswell, C. Guthrie and C. Maeder.
Texas State Univ.-San Marcos and UCSF.
C81
988.3
Comprehensive mechanistic analysis of the
RNA-lariat debranching enzyme.
E.M. Ransey, S. Dey, S. Das
and M. Macbeth. Carnegie Mellon Univ.
C82
988.4
Alternative substrate kinetics of Escherichia
coli ribonuclease P: determination of relative rate constants
by internal competition.
L.E. Yandek, H-C. Lin and M. Harris.
Case Western Reserve Univ.
C83
988.5
Insights into splicing: structure of the yeast
U1 snRNP.
C. van der Feltz, N. Grigorieff and D. Pomeranz
Krummel. Brandeis Univ. and HHMI, Chevy Chase, MD.
989. RNA STRUCTURE AND DYNAMICS
Poster
t
ue
. 7:30
am
—B
oston
C
onvention
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Presentation time: 1:05
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-2:35
pm
C84
989.1
Molecular dynamics study of the stability of the
sarcin/ricin domain of RNA.
M.F. Bruist and C. Cavanaugh.
Univ. of Sciences in Philadelphia.
C85
989.2
Conformational stability of loop E in the potato
spindle tuber viroid.
R.M. Salvo, M.F. Bruist and T. Baumstark.
Univ. of Sciences, Philadelphia and Cornell Univ.
990. RNA STRUCTURE, FUNCTION AND
REGULATION
Poster
t
ue
. 7:30
am
—B
oston
C
onvention
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Presentation time: 1:05
pm
-2:35
pm
C86
990.1
The amyotrophic lateral sclerosis and
frontotemporal dementia-associated C9ORF72 r(GGGGCC)n
hexanucleotide repeat forms extremely stable uni- and multi-
molecular RNA G-quadruplex structures.
K. Reddy, B. Zamiri,
S. Stanley, R. Macgregor and C. Pearson. The Hosp. for Sick
Children and Univ. of Toronto.
991. RNA TRANSPORT AND LOCALIZATION
Poster
t
ue
. 7:30
am
—B
oston
C
onvention
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Presentation time: 1:05
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pm
C87
991.1
Regulation of mRNA export by the PI3 kinase/
AKT signaling pathway.
E.A. Vancor, A.J.C. Quaresma and
J.A. Nickerson. Univ. of Massachusetts Med. Sch.
992. RNA TURNOVER
Poster
t
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. 7:30
am
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Presentation time: 1:05
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pm
C88
992.1
A stress-activated, p38 MAPK-ATF/CREB
pathway regulates the post-transcriptional decay of target
mRNSs.
J. Gao, J.L. Wagnon, R.M. Protacio, G.V. Glazko,
M. Beggs, V. Raj, M.K. Davidson and W.P. Wahls. Univ. of
Arkansas for Med. Sci.
993. REGULATORY THIOL MODIFICATIONS
Poster
t
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. 7:30
am
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Presentation time: 1:05
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C89
993.1
Turnabout is fair play: mutual regulation of
palmitoylation and raft partitioning.
I. Levental and K. Simons.
Univ. of Texas Hlth. Sci. Ctr. at Houston and Max Planck Inst. of
Cell Biol. and Genet., Dresden.
C90
993.2
A redox insensitive triple cysteine mutant of
SirT1 rescues oxidative stress-induced apoptosis.
D. Shao,
J. Fry, R. Zee, V. Kumar, D. Pimentel, R. Cohen and M.
Bachschmid. Boston Univ.
C91
993.3
Modulation of signaling proteins by reversible
cysteine modification.
J.D. Keyes, K. Nelson, D. Parsonage,
L. Daniel, C. Furdui and L. Poole. Wake Forest Univ.
C92
993.4
Oxidation of the Hsp70 BiP protects cells
during ER stress.
C. Sevier, K. Pareja and J. Wang. Cornell
Univ.
994. AUTOPHAGY
Poster
t
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. 7:30
am
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Presentation time: 1:05
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pm
C93
994.1
Role of HSF1 and FoxO3 in proteotoxic stress
induced macroautophagy.
A. Murshid, S.D. Chou, T. Eguchi
and S. Calderwood. Beth Israel Deaconess Med. Ctr., Harvard
Med. Sch.
C94
994.2
Failure of autophagy induction makes multidrug
resistant cells vulnerable to BH3-mimetic gossypol.
J-H. Ahn,
G-H. Jang and M. Lee. Univ. of Incheon, South Korea.
TUESDAY BIOCHEMISTRY
332
C95
994.3
Mitophagy as a quality control mechanism in
Saccharomyces cerevisiae.
H. Abeliovich, M. Zarei, K.T.G.
Rigbolt, R.J. Youle and J. Dengjel. Hebrew Univ. of Jerusalem,
Freiburg Inst. for Adv. Studies, Germany and NINDS, NIH.
C96
994.4
The role of enhanced autophagy in acquired
resistance to new B-Raf inhibitor UI-152.
G-H. Jang, J-H. Ahn
and M. Lee. Univ. of Incheon, South Korea.
C97
994.5
Effects of aging on the heat shock response
and autophagy in human peripheral blood mononuclear
cells.
K.R. Lanphere, S. Schneider, C. Mermier, M. Zuhl, K.
Dokladny and P. Moseley. Univ. of New Mexico.
C98
994.6
B19, a novel monocarbonyl analogue of
curcumin induced human ovarian cancer cells apoptosis
via activation endoplasmic reticulum stress and autophagy
signaling pathway.
J. Xiao, W. Qu, Z. Wang, H. Shi and H.
Zhang. Wenzhou Med. Col., China.
C99
994.7
The effect of HSF-1 and HSP70 on autophagy
regulation.
K. Dokladny, V. Deretic and P.L. Moseley. Univ. of
New Mexico.
C100
994.8
Effect of a six week exercise training program
on proteolytic enzyme activity, ROS generation and autophagy
in the white gastrocnemius and left ventricle of normotensive
and hypertensive rats.
E.M. McMillan, M-F. Paré and J.
Quadrilatero. Univ. of Waterloo, Canada.
C101
994.9
A protocol for screening of autophagy
regulatory genes applying cell sorting and next-generation
sequencing technologies.
W-P. Huang and A-Y. Liu. Natl.
Taiwan Univ.
995. PROTEASES IN CELL REGULATION AND
DISEASE
Poster
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. 7:30
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C102
995.1
Expression of recombinant human neutrophil
cathepsin G in Pichia pastoris.
E.T. Perry, E. Smith and D.
Johnson. East Tennessee State Univ. Quillen Col. of Med.
C103
995.2
Extracellular thimet oligopeptidase is carried
by cell membrane microvesicles of prostate cancer cells.
Y. Liu,
L.A. Bruce and A.J. Wolfson. Wellesley Col.
C104
995.3
Perillyl alcohol and rapamycin-mediated
inhibition of migration and invasion.
T. Sundin, P. Mollica, D.
Peffley and P. Hentosh. Old Dominion Univ.
C105
995.4
Nuclear MMP-2: presence and activity in
cardiac myocytes.
M.Y. Kondo, M.M. Castro, F. Fan and R.
Schulz. Univ. of Alberta.
C106
995.5
Caspase-1 activation is critical for endothelial
activation and early atherogenesis.
Y. Yin, H. Wang and X-f.
Yang. Temple Univ. Sch. of Med.
C107
995.6
The activation of factor VII by a variety of
potential activators.
K. Ke and J. Morrissey. Univ. of Illinois,
Urbana.
C108
995.7
Development of affinity purification systems for
isolation and proteomic analysis of proteases from Tetrahymena
thermophila.
B. Lu, J.R. Carreon and J.W. Straus. Vassar
Col., NY and Ramapo Col., NJ.
C109
995.8
RpoS is directly controlled by ATP levels.
C.
Peterson. Suffolk Univ., MA.
996. PROTEIN FOLDING, MISFOLDING AND
AGGREGATION
Poster
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. 7:30
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C110
996.1
Dual role of the metalloprotease FtsH in
biogenesis of the DrrAB drug transporter.
W. Li. Georgia State
Univ.
C111
996.2
Detection of pathological tau conformers in
cerebrospinal fluid.
Z.M. March, S. Gupta and D.W. Colby.
Univ. of Delaware and Indian Inst. of Technol.-Gandhinagar.
C112
996.3
Antiparallel
b structure in Ab42 oligomers. L.
Gu, C. Liu and Z. Guo. UCLA.
C113
996.4
Probing molecular mechanism of
destabilization and misfolding of human apolipoprotein A-I
in familial amyloidosis.
M. Das, X. Mei, D. Atkinson and O.
Gursky. Boston Univ. Sch. of Med.
C114
996.5
Structural and functional importance of third-
circuit hydrogen bonds within hemolysin A.
M.A. Apolinario
and T.M. Weaver. Univ. of Wisconsin-La Crosse.
C115
996.6
Hydrazines as potential anti-amyloidogenic
agents.
S. Ghosh , C. Schifone, M. Foster, B. Torok, H. Levine
III and M. Torok. Univ. of Massachusetts Boston and Univ. of
Kentucky.
C116
996.7
Synthesis of functional proteins via
bioconjugation.
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