Actual problems of infectious diseases and hiv infection

Partial answer

Absence of answer

*All the above

The characteristic of an unsteady answer of interferon therapy are.

1. 
   Disappearance of markers of viral replication upon completion of course of therapy
   
2. 
   Normalization of activity of ALaT during the course of therapy
   
3. 
   An origin of relapse in next 6 months
   
4. 
   Disappearance of icterus
   
5. 
   *All the above
   

That characteristic of a partial answer of interferon therapy are all, except.

1. 
   *Disappearance of markers of viral replication
   
2. 
   Normalization of activity of ALaT is upon completion of course of therapy
   
3. 
   Disappearance of icterus
   
4. 
   Normalization the state of patient
   
5. 
   Normalization of the size of liver
   

When is interferon therapy effective in the the patient.

1. 
   Normalization of the state of patient
   
2. 
   Normalization of activity of ALaT upon completion of course of therapy
   
3. 
   Disappearance of icterus
   
4. 
   Normalization of the size of liver
   
5. 
   *The markers of viral replication, are determined upon completion of course of therapy
   

What laboratory work-up is needed for confirming the diagnosis of viral hepatitis.

1. 
   Total analysis of blood
   
2. 
   Determination of level of bilirubin
   
3. 
   Determination of activity of aminotransferase
   
4. 
   *Determination of markers of HV in IFA
   
5. 
   All the above
   

What laboratory and instrumental examinations are needed for confirming the diagnosis of viral hepatitis.

1. 
   Complete analysis of blood
   
2. 
   Ultrasound of abdominal region
   
3. 
   Determination of activity of aminotransferase
   
4. 
   *Determination of antigen of viruses
   
5. 
   Duodenal probing
   

What is incubation period for hepatitis B:

1. 
   45 days
   
2. 
   *180 days
   
3. 
   360 days
   
4. 
   90 days
   
5. 
   25 days
   

All the hepatitis have parenteral route of transmission except:

1. 
   *A
   
2. 
   B
   
3. 
   C
   
4. 
   D
   
5. 
   TTV
   

Chronic course is common for viral hepatitis except:

1. 
   *A
   
2. 
   B
   
3. 
   C
   
4. 
   D
   
5. 
   B+C
   

All the following medicines are interferons except:

1. 
   Intron
   
2. 
   Roferon
   
3. 
   Reaferon
   
4. 
   Leukinferon
   
5. 
   *Cycloferon
   

All the following medicines are hepatoprotective agents except:

1. 
   Carsil
   
2. 
   Silibor
   
3. 
   Legalon
   
4. 
   *Lomusol
   
5. 
   Arginine
   

What is mechanism of transmission in viral hepatitis A:

1. 
   Contact
   
2. 
   Transmissive
   
3. 
   Vertical
   
4. 
   *Fecal-oral
   
5. 
   Air-drop
   

What is mechanism of transmission in viral hepatitis B:

1. 
   *Contact
   
2. 
   Transmissive
   
3. 
   Alimentary
   
4. 
   Fecal-oral
   
5. 
   Air-drop
   

What is mechanism of transmission in viral hepatitis C:

1. 
   *Contact
   
2. 
   Transmissive
   
3. 
   Alimentary
   
4. 
   Fecal-oral
   
5. 
   Air-drop
   

What is mechanism of transmission in viral hepatitis D:

1. 
   *Contact
   
2. 
   Transmissive
   
3. 
   Alimentary
   
4. 
   Fecal-oral
   
5. 
   Air-drop
   

What is mechanism of transmission in viral hepatitis E:

1. 
   Contact
   
2. 
   Sexual
   
3. 
   Alimentary
   
4. 
   *Fecal-oral
   
5. 
   Air-drop
   

At inspection of a 8 weeks term pregnant woman HBsAg was found. Level of bilirubin of blood and activity of ALAT were normal. What is necessary to do?

1. 
   *To save pregnancy and conduct the inoculation to newborn against hepatitis B
   
2. 
   Termination of pregnancy
   
3. 
   Termination of pregnancy and conduct treatment by interferon
   
4. 
   To save pregnancy and conduct treatment by lamivudin
   
5. 
   To save pregnancy and ultrasonic inspection of the fetus
   

Diagnosed a patient: chronic hepatitis in the stage of integration. What markers will be in

1. 
   patient in this stage disease?
   
2. 
   HBeAg
   
3. 
   Antibodies to HBeAg
   
4. 
   DNA OF HBV
   
5. 
   Viral DNA-polimerase
   
6. 
   *HBsAg, anti-НBе
   

As etiotropic therapy of sharp and chronic viral hepatitis B utillize:

1. 
   Corticosteroid
   
2. 
   Immunomodulate preparations
   
3. 
   Cytostatics
   
4. 
   Antibiotics
   
5. 
   *Antiviral preparations
   

When did order a patient with virus hepatitis?

1. 
   Non-permanent negative virologic research of defecating
   
2. 
   21 days of normal temperature of body
   
3. 
   Of normalization of level of bilirubinum
   
4. 
   Clinical convalescence and normalization of level of transaminasis
   
5. 
   *Clinical convalescence and no more than triple increase of level of transaminasis
   

Give recommendation for a patient in reconvalensent period of viral hepatitis during a clinical supervision after isolation.

1. 
   A medical supervision during 6 month
   
2. 
   Biochemical inspection
   
3. 
   Abstain from hard physical load
   
4. 
   Temporal contra-indications for prophylactic inoculations
   
5. 
   *All the above
   

Give recommendation for a patient in reconvalensent period of viral hepatitis during a clinical supervision after isolation.

1. 
   *Medical supervision during 6 months, periodic biochemical inspections.
   
2. 
   Control bacteriological examinations
   
3. 
   Full labor investigation
   
4. 
   To continue prophylactic inoculations
   
5. 
   Supervision is not needed
   

Etiotropic therapy of viral hepatitis is.

1. 
   Ribavirin
   
2. 
   Interferon
   
3. 
   Inductors of interferon
   
4. 
   Zefix
   
5. 
   *All the above.
   

Choose the remedies for etiotropic therapy of viral hepatitis.

1. 
   *Ribavirin
   
2. 
   Vaccine
   
3. 
   Normal human immunoprotein
   
4. 
   Hepatoprotector
   
5. 
   Glucocorticoid
   

Choose the remedies for etiotropic therapy for viral hepatitis.

1. 
   Antibiotics
   
2. 
   *Interferon
   
3. 
   Probiotics
   
4. 
   Vaccine
   
5. 
   Normal human immunoprotein
   

The criteria for application of etiotropic therapy in viral hepatitis is.

1. 
   Protracted motion of HBV, HVD
   
2. 
   Any form of HV
   
3. 
   Biochemical activity
   
4. 
   Presence of virus replication
   
5. 
   *All the above.
   

The criteria for application of etiotropic therapy for the patient with HCV.

1. 
   Clinical displays are insignificant
   
2. 
   Icterus is absent
   
3. 
   Moderate biochemical activity
   
4. 
   There is anti-HCV in blood
   
5. 
   *RNA of HCV +
   

Factors which are indications of successful interferon therapy in HV infections are all, except.

1. 
   Level of ALaT not more than 2-3 norm
   
2. 
   Low titre of HCV after the treatment
   
3. 
   Absence of cholestasis
   
4. 
   2th and 4th genotypes of HCV
   
5. 
   *Expressed fibrosis
   

Indirect action of interferon therapy.

1. 
   Influenza-like syndrome
   
2. 
   Nausea
   
3. 
   Itching
   
4. 
   Para-hypnosis
   
5. 
   *All the above
   

Indirect action of interferons.

1. 
   Flatulence
   
2. 
   Diarrhea
   
3. 
   Nausea
   
4. 
   Depression
   
5. 
   *All the above
   

Indirect action of interferon therapy are all except.

1. 
   Influenza-like syndrome
   
2. 
   Nausea
   
3. 
   Depression
   
4. 
   Intensification of autoimmune diseases
   
5. 
   *Progress of fibrosis
   

Basic principles of antiviral therapy for viral hepatitis.

1. 
   Individual selection of dose and rhythm of application of preparations
   
2. 
   Duration of introduction of preparations
   
3. 
   Control of amount of erytrocytes, leucocytes and thrombocytes, in blood
   
4. 
   Control of iron level in blood
   
5. 
   *All the above
   

Contra-indications for antiviral therapy of viral hepatitis.

1. 
   Decompensatory cirrhosis of liver
   
2. 
   Thrombocytopenia <50000 in 1 мм3
   
3. 
   Psychic disorders
   
4. 
   Leucocytopenia <1500 in 1 мм3
   
5. 
   *All the above
   

Contra-indications for antiviral therapy of viral hepatitis.

1. 
   Decompensatory cirrhosis of liver
   
2. 
   Autoimmune disease
   
3. 
   Alcoholism and other drug addictions
   
4. 
   Coinfection by HIV
   
5. 
   *All the above
   

Choose the indexes of efficiency of interferon therapy.

1. 
   *Disappearance| of markers of viral replication
   
2. 
   Improvement of the general state
   
3. 
   Normalization of the liver size
   
4. 
   Disappearance of icterus
   
5. 
   All the above
   

Choose the indexes of efficiency of interferon therapy.

1. 
   Improvement of the general state
   
2. 
   *Normalization of activity of ALaT
   
3. 
   Normalization of the liver size
   
4. 
   Disappearance of icterus
   
5. 
   All the above
   

Types of answer for interferon therapy are.

1. 
   Stable remission
   
2. 
   Unsteady
   
3.