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2013 № 1

Mediko-biologicheskie i sotsial'no-psikhologicheskie problemy bezopasnosti v chrezvychaynykh situatsiyakh [Medical-Biological and Socio-Psychological Problems of Safety in Emergency Situations]. 2013. N 1. Pp. 5–9.



Dezhurny L.I., Boyarintsev V.V., Turin M.V. O sozdanii edinoi sistemy okazaniya pervoi pomoshchi v Rossiiskoi Federatsii [On creation of a unified system of first aid provision in the Russian Federation]

Teaching and Research Medical Center, Executive Office of the President of Russia

(Russia, 121352, Moscow, Stavropolskaya Str., 10);

The Nikiforov Russian Center of Emergency and Radiation Medicine, EMERCOM of Russia

(Russia, 194044, Saint-Petersburg, Academica Lebedeva Str., 4/2);

The Kirov Military Medical Academy (194044, Russia, Saint-Petersburg, Academica Lebedeva Str., 6)


Dezhurnyi Leonid Igorevich – Dr. Med. Sci. Prof., Leading researcher, Federal Research Institute for Health Organization and Informatics (Russia, 127254, Moscow, Dobrolubova Str., 11); e-mail: DL@npfmiral.ru;

Boyarintsev Valerii Vladimirovich – Dr. Med. Sci. Prof., Teaching and Research Medical Center, Executive Office of the President of Russia (Russia, 121352, Moscow, Stavropolskaya Str., 10); e-mail: wpx@mail.ru;

Tyurin Mikhail Vasil'evich – Dr. Med. Sci. Prof., The Nikiforov Russian Center of Emergency and Radiation Medicine, EMERCOM of Russia (Russia, 194044, Saint-Petersburg, Academica Lebedeva Str., 4/2), The Kirov Military Medical Academy (Russia, 194044, Saint-Petersburg, Academica Lebedeva Str., 6); e-mail: mixail_turin@mail.ru
Abstract. The need for a uniform system of first aid provision in Russia is discovered. This system shall include: regulatory framework for organizing the provision of first aid; measures to promote and enhance the motivation; training subsystem; equipping first aid providers with the necessary means and medicines; subsystem for accounting and performance analysis. Regulations on first aid are analyzed in detail, along with their development prospects.

Keywords: first aid, urgent conditions, accidents, healthcare organization, health protection.
References

1. Agarkov N. M. Differentsial'nye kriterii i klassifikatsiya bytovogo travmatizma [Differential criteria and classification of home accidents]. Problemy sotsial'noi gigieny i istorii meditsiny [Problems of social hygiene and medical history]. 1995. N 2. Pp. 30–32. (In Russ.)

2. Asadullin Sh.G. Deti v ChS: ob"ektivnaya neobkhodimost' perestroiki sistemy okazaniya ekstrennoi i neotlozhnoi meditsinskoi pomoshchi [Children in Emergencies: the objective necessity of restructuring the system of emergency and urgent care]. Deti v chrezvychainykh situatsiyakh: tezisy dokladov foruma [Children in Emergencies: forum abstracts]. Moskva. 2003. Pp. 13–14. (In Russ.)

3. Global'nyi krizis v oblasti bezopasnosti dorozhnogo dvizheniya : OON, General'naya assambleya (A/60/181, A/58/228) : doklad General'nogo sekretarya 07.08.2003 [Global crisis in road safety: the UN General Assembly (A/60/181, A/58/228): Report of the Secretary-General 07.08.2003.]. URL: http://daccess-dds-ny.un.org/. (In Russ.)

4. Mikhailovich V.A., Miroshnichenko A.G. Rukovodstvo dlya vrachei skoroi pomoshchi [Guide for ambulance physicians]. Sankt-Peterburg. 2005. 703 p. (In Russ.)

5. O vnesenii izmenenii v Osnovy zakonodatel'stva Rossiiskoi Federatsii ob okhrane zdorov'ya grazhdan i otdel'nye zakonodatel'nye akty Rossiiskoi Federatsii: federal'nyi zakon ot 25.11.2009 N 267-FZ [On amendments to the Fundamentals of Russian legislation on health care and some legislative acts of the Russian Federation: Federal Law of 25.11.2009 N 267-FZ]. URL: consultant.ru/. (In Russ.)

6. O voennom polozhenii: federal'nyi konstitutsionnyi zakon ot 30.01.2002 N 1-FKZ [On Martial Law: Federal constitutional law of 30.01.2002 N 1-FKZ]. Sobranie zakonodatel'stva Rossii [Collected legislation of Russia]. 2002. N 5. Article 375. (In Russ.)

7. O grazhdanskoi oborone: federal'nyi zakon ot 12.12.1998 N 28 FZ [Civil Defense: Federal law of 12.12.1998 N 28 FZ]. Sobranie zakonodatel'stva Rossii [Collected legislation of Russia]. 1998. N 7. Article 799. (In Russ.)

8. O zashchite naseleniya i territorii ot chrezvychainykh situatsii prirodnogo i tekhnogennogo kharaktera: federal'nyi zakon ot 21.12.1994 N 68-FZ [On protection of population and territories from natural and man-made disasters: the federal law of 21.12.1994 N 68-FZ]. Sobranie zakonodatel'stva Rossii [Collected legislation of Russia]. 1994. N 35. Article 3648. (In Russ.)

9. O pervoi pomoshchi Rossii: prikaz Ministerstva zdravookhraneniya i sotsial'nogo razvitiya Rossii ot 17.05.2010 N 353n [On first aid in Russia: Order of the Ministry of Health and Social Development of Russia of 17.05.2010 N 353n]. Rossiiskaya gazeta [Russian newspaper], 16.07.2010. (In Russ.)

10. O poryadke otneseniya territorii k gruppam po grazhdanskoi oborone: postanovlenie Pravitel'stva Rossii ot 3.10.1998 N 1149 [Procedure of ranking areas to groups of civil defense: the resolution of the Government of Russia of 3.10.1998 N1149]. Sobranie zakonodatel'stva Rossii [Collected legislation of Russia]. 1998. N 41. Article 5024. (In Russ.)

11. O federal'noi tselevoi programme «Povyshenie bezopasnosti dorozhnogo dvizheniya v 2006–2012 goda»: postanovlenie Pravitel'stva Rossii ot 20.02.2006 N 100 [Federal Targeted Program "Improving road safety in 2006-2012": Decree of the Government of Russia of 20.02.2006 N 100]. Sobranie zakonodatel'stva Rossii [Collected legislation of Russia]. 2006. N 9. Article 1020. (In Russ.)

12. O chrezvychainom polozhenii: federal'nyi konstitutsionnyi zakon ot 30.05.2001 N 3-FKZ [The State of Emergency: the federal constitutional law of 30.05.2001 N 3-FKZ]. Sobranie zakonodatel'stva Rossii [Collected legislation of Russia]. 2001. N 23. Article 2277. (In Russ.)

13. Ob osnovakh okhrany zdorov'ya grazhdan v Rossiiskoi Federatsii: federal'nyi zakon ot 21.11.2011 N 323-FZ [On the basis of health protection in the Russian Federation: Federal Law of 21.11.2011 N 323-FZ]. URL: http://base.garant.ru/12191967/. (In Russ.)

14. Ob utverzhdenii perechnya sostoyanii, pri kotorykh okazyvaetsya pervaya pomoshch', i perechnya meropriyatii po okazaniyu pervoi pomoshchi : prikaz Ministerstva zdravookhraneniya i sotsial'nogo razvitiya Rossii ot 04.05.2012 N 477n [Approving the list of states in which to provide first aid, and a list of measures for first aid: Order of the Ministry of Health and Social Development of the Russian Federation of 04.05.2012 N 477n]. Rossiiskaya gazeta [Russian newspaper], 23.05.2012. (In Russ.)

15. Sumin S.A. Neotlozhnye sostoyaniya [Emergency conditions]. Moskva. 2005. 752 p. (In Russ.)

16. Sethi D. [et al.]. Travmatizm i nasilie v Evrope [Injuries and violence in Europe]. Italiya, 2006. 26 p. (In Russ.)

17. Khrupkin V.I. Organizatsiya neotlozhnoi spetsializirovannoi khirurgicheskoi pomoshchi naseleniyu v chrezvychainykh situatsiyakh [Organization of emergency specialized surgical care to the population in emergency situations]. Meditsina katastrof, skoraya i neotlozhnaya pomoshch' i ekstremal'naya meditsina : materialy konferentsii [Disaster medicine, emergency and urgent care and emergency medicine: proceedings of the conference]. Moskva. 2000. Pp. 162–165. (in Russ.)

18. Yankin Yu.M., Bukhtiyarova E.V. Obrashchaemost' za skoroi meditsinskoi pomoshch'yu razlichnykh sotsial'nykh grupp naseleniya [Resort of various social groups to emergency care]. Skoraya meditsinskaya pomoshch' [Emergency medical care] 2005. N 2. Pp. 9–12.

19. Cohen L., Swift S. The spectrum of prevention: developing a comprehensive approach to injury prevention. Injury Prevention. 1999. N 5. Pp. 203–207.

20. Marson A., Thomson J. The influence of prehospital trauma care on traffic accident mortality. J. of Trauma. 2001. Vol. 50. Pp. 917–920.

Received 26.10.2012


Mediko-biologicheskie i sotsial'no-psikhologicheskie problemy bezopasnosti v chrezvychaynykh situatsiyakh [Medical-Biological and Socio-Psychological Problems of Safety in Emergency Situations]. 2013. N 1. Pp. 10–14.



Kotenko P.K., Kireev S.G., Martynov A.I. Opyt primeneniya polevoi mobil'noi meditsinskoi gruppy MChS Rossii v khode provedeniya gumanitarnoi operatsii na territorii Respubliki Yuzhnaya Osetiya v avguste–sentyabre 2008 goda [Experience of using the EMERCOM field mobile medical unit in the humanitarian operation in the Republic of South Ossetia in August – September 2008]
The Nikiforov Russian Center of Emergency and Radiation Medicine, EMERCOM of Russia

(Russia, 194044, Saint-Petersburg, Academica Lebedeva Str., 4/2)


Kotenko Petr Konstantinovich – Dr. Med. Sci. Prof., of Nikiforov Russian Center of Emergency and Radiation Medicine, EMERCOM of Russia (Russia, 194044, Saint-Petersburg, Academica Lebedeva Str., 4/2), e-mail: medicine@arcerm.spb.ru.

Kireev Sergey Grigor'yevich – PhD Med. Sci., Head of the Department, Hospital N 40 (Russia, 197706, Saint-Petersburg, Borisova Str. 9, litera B), е-mail: serg-kir@mail.ru;

Martynov Andrei Ivanovich – PhD Med. Sci., director of the sanatorium "Druzhba" (Russia, 354000, Krasnodar region, Sochi, Beregovaya Str., 8/25); е-mail: may_doc@mail.ru
Abstract. Experience of using the EMERCOM field mobile medical unit in the humanitarian operation in the Republic of South Ossetia in August – September 2008 has been summarized. Normative basis for its establishment and operation is presented, the conditions having the most significant impact on the organization of work are revealed. Presented are deployment chart and some results of work of the group for rendering medical assistance to EMERCOM professionals, employees of the federal bodies of executive power of the power unit, the local population.

Keywords: humanitarian operation, medical care and treatment, medical maintenance, EMERCOM field mobile medical unit.
References

1. Bezopasnost' v chrezvychainykh situatsiyakh. Lechebno-evakuatsionnoe obespechenie naseleniya. Obshchie trebovaniya: GOST R 22.3.02-94 [Safety in emergencies. Medical-evacuation support for population. General requirements: State standard R 22.3.02-94]. URL: http://ohranatruda.ru/ot_biblio/ normativ/data_normativ/4/4803/index.php. (In Russ.)

2. Grazhdanskaya zashchita : entsiklopediya [Civil protection: encyclopedia]. Ed. S.K. Shoigu. Voronezh. 2009. Vol. 1. P. 329. (In Russ.)

3. Kornyushko I.G, Yakovlev S.V., Vladimirov E.V. Opyt primeneniya mobil'nykh formirovanii Sluzhby meditsiny katastrof Minoborony Rossii v lokal'nykh voinakh i vooruzhennykh konfliktakh [Experience of using mobile units of Disaster Medicine Services of Russian Defense Ministry in local wars and armed conflicts]. Voenno-meditsinskii zhurnal [Military medical journal]. 2011. N 9. Pp. 12–20. (In Russ.)

4. Kotenko P.K., Benya F.M., Alborov Z.Ts. Primenenie 106 otdel'nogo meditsinskogo batal'ona v khode operatsii po prinuzhdeniyu Respubliki Gruziya k miru (01.8–27.08.2008) [Application of separate medical battalion No 106 during peace enforcement in the Republic of Georgia (01.8-27.08.2008)]. Aktual'nye voprosy meditsinskogo obespecheniya voisk v mirnoe i voennoe vremya: materialy konferentsii [Topical issues of medical support in peacetime and wartime: conference materials]. Sankt-Peterburg. 2009. Pp. 121–122. (In Russ.)

5. Ob utverzhdenii Kontseptsii sovershenstvovaniya meditsinskogo obespecheniya sistemy MChS Rossii na period do 2020 goda i Plana osnovnykh meropriyatii realizatsii pervogo etapa Kontseptsii na 2009–2011 gody : prikaz MChS Rossii ot 20.11.2008 N 710 [On approval of the Concept of improving medical care of Russia Emercom for the period up to 2020 and the Plan of the main activities to implement the first phase of the Concept for 2009-2011: the order of the Russian Emercom of 20.11.2008 N 710]. Moskva. 2008. 14 p. (In Russ.)

6. Kornyushko I.G. [et al.]. Organizatsiya meditsinskogo obespecheniya voisk v khode operatsii po prinuzhdeniyu Gruzii k miru [Organization of medical support of troops during the operation to force Georgia to peace]. Voenno-meditsinskii zhurnal [Military medical journal]. 2009. N 2. Pp. 4–6. (In Russ.)

7. Samokhvalov I.M. [et al.]. Osobennosti okazaniya spetsializirovannoi khirurgicheskoi pomoshchi ranenym v khode kontrterroristicheskikh i mirotvorcheskoi operatsii na Severnom Kavkaze [Features of specialized surgical care to the wounded during counter-terrorist and peacekeeping operations in the North Caucasus]. Voenno-meditsinskii zhurnal [Military medical journal]. 2012. N 7. Pp. 4–10. (In Russ.)

8. Belevitin A.B. [et al.]. Osobennosti organizatsii okazaniya meditsinskoi pomoshchi ranenym pri provedenii operatsii po prinuzhdeniyu Gruzii k miru (2008) [Features of medical care to the wounded during the operation to force Georgia to peace (2008)]. Vestnik Rossiiskoi voenno-meditsinskoi akademii [Bulletin of Russian Military medical Academy]. 2009. N 5. Pp. 5–18. (In Russ.)

9. O sozdanii polevoi mobil'noi meditsinskoi gruppy v Yuzhnom regional'nom poiskovo-spasatel'nom otryade : prikaz MChS Rossii ot 04.08.2005 N 613 [On establishment of field mobile medical team in the Southern regional search and rescue team: the order of the Russian Emercom of 04.08.2005 N 613]. Moskva. 2005. 2 p. (In Russ.)

Received 14.01.2013

Mediko-biologicheskie i sotsial'no-psikhologicheskie problemy bezopasnosti v chrezvychaynykh situatsiyakh [Medical-Biological and Socio-Psychological Problems of Safety in Emergency Situations]. 2013. N 1. Pp. 15–19.



Batсkov S.S., Ushakov D.Yu., Savvin Yu.Yu., Pyatibrat E.D. Osobennosti funktsional'nogo sostoyaniya organizma v protsesse adaptatsii k ekstremal'nomu vozdeistviyu magnitnykh polei [Features of body functional state in the process of adaptation to extreme magnetic field influence]
The Nikiforov Russian Center of Emergency and Radiation Medicine, EMERCOM of Russia

(Russia, 194044, Saint-Petersburg, Academica Lebedeva Str., 4/2);

The Kirov Military Medical Academy (Russia, 194044, Saint-Petersburg, Academica Lebedeva Str., 6)
Batskov Sergei Sergeevich – Dr. Med. Sci. Prof., Head of Clinical Department of Gastroenterology and Hepatology, the Nikiforov Russian Center of Emergency and Radiation Medicine, EMERCOM of Russia (Russia, 194044, Saint-Petersburg, Academica Lebedeva Str., 4/2); e-mail: medicine@arcerm.spb.ru;

Ushakov Dmitrii Yur'evich – head of functional diagnostics office (Russia, 354010, Krasnodar region, Sochi, Vinogradnaya Str., 35); e-mail ushakov_d@yandex.ru;

Savvin Yurii Yur'evich – clinical intern, Department of Nervous Diseases, Kirov Military Medical Academy (Russia, 194044, Saint-Petersburg, Academica Lebedeva Str., 6); e-mail: saway@mail.ru;

Pyatibrat Elena Dmitrievna – Dr. Med. Sci., assistant lecturerer, Department of Hospital Therapy, the Kirov Military Medical Academy (Russia, 194044, Saint-Petersburg. Academica Lebedeva Str., 6); e-mail: 5brat@bk.ru


Abstract. Body functional parameters have been analyzed in the young and middle-aged persons under the influence of dynamic magnetic fields of complex structure. There have been revealed peculiarities of changes in neurodynamic functions, non-specific resistance, blood circulation and breathing physiologic systems during adaptation to the influence of dynamic magnetic fields of complex structure. Body functional parameters under the influence of dynamic magnetic fields of complex structure were compared in persons of different ages.

Keywords: magnetic field, body functional state, adaptation, non-specific resistance, neurodynamic functions, magnetic abnormalities.
References

1. Agadzhanyan N.A., Makarova I.I. Vliyanie geomagnitnoi aktivnosti na kardiorespiratornuyu sistemu [Effect of geomagnetic activity on cardiorespiratory system]. Aviakosmicheskaya i ekologicheskaya meditsina [Aerospace and environmental medicine]. 2007. Vol. 35, N 5. Pp. 46–49. (In Russ.)

2. Bukalov A.V. Fenomen geliofizicheskogo imprintinga i vliyanie solnechnoi aktivnosti na prodolzhitel'nost' zhizni cheloveka [Heliophysical imprinting phenomenon and the influence of solar activity on the human lifespan]. Slabye i sverkhslabye polya i izlucheniya v biologii i meditsine: materialy kongressa [Weak and super-weak fields and radiation in biology and medicine: proceedings of congress]. Sankt-Peterburg. 2006. P. 139. (In Russ.)

3. But'eva I.V., Shveinova T.G., Devyatova S.S. Klimat i zdorov'e cheloveka [Climate and human health]. Leningrad. 1988. Vol. 2. Pp. 55–59. (In Russ.)

4. Grigor'ev O.A., Merkulov A.V. Problema ekologicheskikh normativov v usloviyakh elektromagnitnogo zagryazneniya okruzhayushchei sredy [The problem of environmental regulations in terms of electromagnetic pollution]. Elektromagnitnye polya i zdorov'e cheloveka. Fundamental'nye i prikladnye issledovaniya: materialy konferentsii [Electromagnetic fields and human health. Basic and applied research: proceedings of the conference]. Moskva. 2002. Pp. 24–46. (In Russ.)

5. Duving V.G., Malinina Yu.A., Voevodin V.I. Modelirovanie vozdeistviya elektromagnitnogo polya vysokovol'tnykh linii elektroperedach na gidrobiologicheskie ob"ekty [Modeling the impact of electromagnetic fields of the high-voltage power lines on hydrobiological objects]. Elektromagnitnaya bezopasnost': problemy i puti resheniya: materialy konferentsii [Electromagnetic safety: problems and solutions: conference materials]. Saratov. 2000. Pp. 32–41. (In Russ.)

6. Evdokimov V.I. Kompleksnaya otsenka sanitarnogo neblagopoluchiya territorii Kurskoi magnitnoi anomalii [Comprehensive assessment of health disadvantage in the Kursk Magnetic Anomaly]. Zdravookhranenie Rossiiskoi Federatsii [Public Health of the Russian Federation]. 2003. N 3. Pp. 28–20. (In Russ.)

7. Ivanov A.A. [et al.]. Instruktsiya po primeneniyu testa automikroflory kozhi u cheloveka dlya vyyavleniya kontingentov i otdel'nykh lits s povyshennym riskom zabolevaniya [Instructions for using the test for human skin automicroflora to identify groups and individuals at increased risk]. Moskva. 1988. 6 p. (In Russ.)

8. Nikitina V.V. Sravnitel'nyi analiz vliyaniya magnitnykh polei razlichnoi intensivnosti v eksperimente [Comparative analysis of the influence of magnetic fields of different intensities in the experiment]. Voprosy kurortologii, fizioterapii i lechebnoy fizicheskoy kul'tury [Questions of balneology, physical therapy and exercises]. 2002. N 3. Pp. 34–35. (In Russ.)

9. Novozhilov V.K. Rol' meteogeliofaktorov i pollyutantov v razvitii oslozhnenii serdechno-sosudistykh zabolevanii v g. Krasnoyarske [Role of meteoheliofactors and pollutants in the development of complications of cardiovascular disease in Krasnoyarsk]. Krasnoyarsk. 1996. 22 p. (In Russ.)

10. Ragul'skaya M.V. Svyaz' periodicheskikh protsessov v organizme cheloveka, obuslovlennykh ritmikoi vneshnei sredy, s variatsiyami magnitnogo polya Solntsa [Relationship of periodic processes in the human body due to rhythm of the environment with variations of the magnetic field of the Sun]. Biomeditsinskaya tekhnika i radioelektronika [Biomedical engineering and radioelectronics]. 2004. N 1/2. Pp. 3–8. (In Russ.)

11. Serpov B.Yu. Bezopasnost' zhiznedeyatel'nosti cheloveka v zonakh geofizicheskikh anomalii Evropeiskoi Rossii [Human safety in areas of geophysical anomalies in European Russia]. Sankt-Peterburg. 2005. 128 p. (In Russ.)

12. Fatkhutdinova L.M. Vliyanie elektromagnitnykh polei chastotoi do 400 kGts na nervnuyu sistemu. Meditsina truda i promyshlennaya ekologiya [Occupational medicine and industrial ecology]. 2001. N 9. Pp. 20–22.

13. Binhi V. Stochastic dynamics of magnetosomes and a mechanism of biological orientation in the geomagnetic field. Bioelectromagnetks. 2006. Vol. 27, N 1. Pp. 58–63.

14. Binhi V., Blackman C. Analysis of the structure of magnetic fields that induced inhibition of stimulated neurite outgrowth. Bioelectromagnetics. 2005. Vol. 26, N 8. Pp. 684–689.

15. Engstrum S., Bowman J. Magnetic resonances of tons in biological systems. Bioelectromagnetics. 2004. Vol. 25, N 1. P. 620–630.

Received 03.12.2012

Mediko-biologicheskie i sotsial'no-psikhologicheskie problemy bezopasnosti v chrezvychaynykh situatsiyakh [Medical-Biological and Socio-Psychological Problems of Safety in Emergency Situations]. 2013. N 1. Pp. 19–23.



Markova I.A., Komlev A.D., Kuzyaev A.I., Kolosova M.V. Sistemnoe vospalenie i legochnaya arterial'naya gipertenziya u likvidatorov posledstvii avarii na Chernobyl'skoi AES s khronicheskoi obstruktivnoi bolezn'yu legkikh [Systemic inflammation and pulmonary arterial hypertension in Chernobyl clean-up workers with chronic obstructive pulmonary disease]
The Nikiforov Russian Center of Emergency and Radiation Medicine, EMERCOM of Russia

(Russia, 194044, Saint-Petersburg, Academica Lebedeva Str., 4/2)


Markova Izana Anatolqevna – Head of Pulmonology Department, The Nikiforov Russian Center of Emergency and Radiation Medicine, EMERCOM of Russia (Russia, 194044, St. Petersburg, Academica Lebedeva Str., 4/2);

Komlev Aleksandr Dmitrievich – PhD Med. Sci., Head of Clinical Department of Pulmonology and Allergology, the Nikiforov Russian Center of Emergency and Radiation Medicine, EMERCOM of Russia (Russia, 194044, Saint-Petersburg, Academica Lebedeva Str., 4/2);

Kuzyaev Aleksandr Ivanovich – PhD Med. Sci., senior research associate, Nikiforov Russian Center of Emergency and Radiation Medicine, EMERCOM of Russia (Russia, 194044, St. Petersburg, Academica Lebedeva Str., 4/2); aakuzyaev@gmail.com;

Kolosova Marina Viktorovna – senior research associate, Nikiforov Russian Center of Emergency and Radiation Medicine, EMERCOM of Russia (Russia, 194044, St. Petersburg, Academica Lebedeva Str., 4/2)


Abstract. Mechanisms of diffuse pneumosclerosis and endotheliitis of the pulmonary arteries were assessed in the Chernobyl clean-up workers. Radiation (inhalation) lung lesions additionally contributed to systemic inflammation. We investigated the degree of systemic inflammation reflected by circulating levels of C-reactive protein (CRP), tumor necrosis factor-alpha (TNF-α) and interleukin-6 (IL-6) in Chernobyl accident liquidators with chronic obstructive pulmonary disease (COPD) with/without pulmonary arterial hypertension. Increased systolic pulmonary artery pressure (SPPA), which was detected in Chernobyl clean-up workers with COPD more frequently, correlated with higher levels of CRP and TNF-α. This may indicate a pathogenic role of systemic inflammation in the pathogenesis of pulmonary arterial hypertension in patients with COPD.

Keywords: chronic obstructive pulmonary disease, pulmonary arterial hypertension, systemic inflammation, Chernobyl clean-up workers.
References

  1. Bychkovskaya I.B., Stepanov R.P., Fedortseva R.F., Sarapul'tseva E.I. Osobye effekty malykh doz i problema prodolzhitel'nosti zhizni zhivotnykh i cheloveka [Special effects of low-dose radiation and lifespan of humans and animals]. Mediko-biologicheskie i sotsial'no-psikhologicheskie problemy bezopasnosti v chrezvychaynykh situatsiyakh [Medical-Biological and Socio-Psychological Problems of Safety in Emergency Situations]. 2011. N 2. Pp. 58–64. (In Russ.)

  2. Sysoev K.A., Kalinina N.M., Bakhtin M.Yu., Nikiforov A.M. Produktsiya interleikina-1-beta i faktora nekroza opukholi al'fa in vivo i in vitro u likvidatorov posledstvii avarii na Chernobyl'skoi AES s serdechno-sosudistoi patologiei [Production of interleukin-1-beta and tumor necrosis factor alpha in vivo and in vitro in liquidators of the Chernobyl accident with cardiovascular disease]. Meditsinskaya immunologiya [Medical immunology]. 2000. Vol. 2, N 1. Pp. 53–58. (In Russ.)

  3. Barbera J.A., Peinado V.I., Santos S. Pulmonary hypertension in chronic obstructive pulmonary disease. Eur. Respir. J. 2003. Vol. 21. Pp. 892–905.

  4. Elstein D., Nir A., Klutstein M. [et al.]. C-reactive protein and NT-proBNP as surrogate markers for pulmonary hypertension in Gaucher disease. Blood Cells Mol. Dis. 2005. Vol. 34. Pp. 201–205.

  5. Cracowski J.L., Yaici A., Sitbon O. [et al.]. Évaluation prognostique de biomarqueurs dans l’hypertension artérielle pulmonaire. Rev. Mal. Respir. 2004. Vol. 21. Pp. 1137–1143.

  6. Pauwels R.A., Buist A.S., Calverley M.A. [et al.]. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: NHLBI/WHO Global Initiative for Chronic Obstructive Lung Disease (GOLD) Workshop summary. Am. J. Respir. Crit. Care Med. 2001. Vol. 163. Pp. 1256–1276.
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