PHYTOCHEMICAL INVESTIGATION OF Artemisia persica FROM THE FLORA OF UZBEKISTAN J.F. Umaraliev 1,3 , A.A. Ganiev 2 , N.B. Begmatov 1,2 , Kh.M. Bobakulov 2 , Zhao Bo 1 , N.D. Abdullaev 2 , H.A. Aisa 1 1) Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Urumqi 830011, China, E-mail: haji@ms.xjb.ac.cn 2) Acad. S. Yu. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, 77, M. Ulugbek str., 100170, Tashkent, Uzbekistan, khayrulla@rambler.ru 3) University of Chinese Academy of Science, 100039, Beijing, P. R. China The genus
Artemisia L . is one of the largest in the
Asteraceae family and is
interesting with respect to chemistry, because it is the source of many secondary
metabolites including terpenoids, flavonoids, and coumarins [1]. The
Artemisia species
commonly known as mugwort, wormwood and sagebrush are reported to possess
various pharmacological activities such as antimicrobial, antioxidant, anticonvulsant
agent, anticoagulant, antidiabetic, antispasmodic, anthelmintic, anticancer, colds,
anticolic, anticoughs, cardiac stimulant, dyspepsia, febrifuge, insecticidal, headaches,
anti-inflammatory, antimalarial, stomachic and antiulcer etc. [2].
We have investigated aerial part of
A. persica collected in Namangan Region of the
Uzbekistan. Air-dried raw material was extracted exhaustively with EtOH (96-70%) at
room temperature. The chloroform fraction was chromatographed over a column with
silica gel by elution with
n -hexane:CHCl
3
:MeOH. Three compounds (
