Organizing co mmittee

CHEMICAL COMPOSITION OF THE UNSAPONIFIABLE 
FRACTION PLANT Adonis turkestanica 
N.M. Mamatkulova, Kh.M. Bobakulov, T.T. Khamraev, I.M. Zhumaboeva,
N.K. Khidyrova
S.Yu. Yunusov Institute of the Chemistry of Plant Substances Academy of sciences of the 
Republic of Uzbekistan st. Mirzo-Ulugbek, 77, 100170 Tashkent 
e-mail: [e-mail] 
Adonis turkestanica
is a medicinal plant of the Ranunculaceae family, approved for 
use as medicines, like other types of Adonis. The plant contains 0.07-0.15% cymarin, 
adonitoxin, adonivernit, saponins and phytosterols. For medicinal purposes, the aerial 
part of the plant is used. In folk medicine, infusions and decoctions of the aerial part of 
the plant are used for fevers, dropsy, jaundice, infectious diseases, typhoid, influenza, 
scarlet fever, and as a sedative for the central nervous system. 
Based on the foregoing, it was of interest to study the chemical composition of the 
aerial parts of plants. What was obtained alcohol extract using ultrasonic mixing. 
Further, hexane, chloroform, ethyl acetate and water-soluble fractions were obtained by 
re-extraction. As well as the unsaponifiable fraction according to the method with the 
corresponding yields of 10%, 8%, 7.5% and 74.5%. The chemical composition of the 
unsaponifiable and hexane fractions was studied using the GC/MS method; as a result, 
19 and 18 compounds were identified, respectively. 
The main components of the unsaponifiable fraction are diterpene alcohol phytol 
(53.78%), saturated, unsaturated and aromatic hydrocarbons (31.44%), alcohols (4.93%) 
and their esters (0.49%), hexahydrofarnesyl acetone (1.5%), (9
E
,12
E
,15
E
)-9,12,15-
Octadecatrien-1-ol (2.8%), provedol (0.7%) and 2,7-dimethyl-1-octanol (0.7%)(
Z
)-14-
tricosenyl format (1.9%). 
The hexane fraction mainly contains fatty acid esters (53.73%), and eicosanotriene - 
midic acid (ω-9-acid) is rarely found in plant objects, it is synthesized mainly in animals 
and humans. In addition, it contains hydrocarbons - 27.51, diterpene alcohol - phytol 
8.60%, cytronelyl isobutyrate 0.96%. 
Thus, the chemical composition of the unsaponifiable and hexane fraction of the 
aerial part of the plant 
Adonis turkestanica
was studied by GC/MS. As a result, 19 and 
18 compounds, respectively, were identified that are of interest in medicine and 
cosmetology. 

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Poster presentation 
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