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It is crucial that each daughter cell receives an identical copy of the DNA when a cell divides. DNA
replication is the process that makes this happen. Before the cell enters mitosis or meiosis, during the synthesis
phase, also known as the S phase, of the cell cycle, DNA replication takes place. An indication of how DNA is
copied was given by the clarification of the double helix's structure. Recall that adenine nucleotides pair with
thymine nucleotides, and cytosine with guanine. This means that the two strands are complementary to each
other. For example, a strand of DNA with a nucleotide sequence of AGTCATGA will have a complementary
strand with the sequence TCAGTACT (Figure 40). Having one strand makes it possible to recreate the other
strand because the two strands complement one another. According to this replication model, the double helix's
two strands split apart during the process and each one acts as a template
for the copying of the new
complementary strand.
Each of the two strands that make up the double helix acts as a template from which new strands are
copied during DNA replication. The parental or "old" strand and the new strand will complement one another.
One new daughter strand and one new parental strand make up each new double strand. Semiconservative
replication is what is meant by this. When
two DNA copies are created, they are equally divided into two
daughter cells and have an identical nucleotide base sequence.
Figure 40.
Because the two strands of DNA are
complementary, the correct base sequence for one strand can
be generated from the base sequence for the other strand.
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