Organizing co mmittee

CHEMICAL STUDY OF TERPENOIDS AND PHENOLIC 
COMPOUNDS OF PLANTS USED IN FOLK MEDICINE OF 
UZBEKISTAN
 
E. Kh. Botirov 
S.Yu. Yunusov Institute of the Chemistry of Plant Substance, Academy of Science of the 
Republic of Uzbekistan, 
100170, Tashkent, 77 M. Ulugbek str., 
e-mail: [e-mail]  
In the laboratory of chemistry of terpenoids and phenolic compounds of the Institute 
of Chemistry of Plant Substances of the Academy of Sciences of the Republic of 
Uzbekistan, fundamental research work is being carried out to study terpenoid and 
phenolic compounds of plants used in folk medicine in Uzbekistan and have not passed 
the necessary verification by means of modern pharmacology, developing methods for 
their isolation, establishing the chemical structure, study of the relationship between 
structure and biological activity. 
The purpose of the ongoing research is to create scientific foundations for the 
development of drugs with adaptogenic, hepatoprotective, hypolipidemic, anticoagulant, 
antioxidant, neurotropic, antihypoxic and anti-inflammatory properties. A chemical 
analysis of terpenoids and phenolic compounds of previously unexplored or poorly 
studied plants of the families 
Asteraceae, Apiaceae, Fabaceae, Polygonaceae, 
Lamiaceae, Geraniaceae
was carried out, rich natural sources of terpenoids and 
phenolic compounds were identified. 
More than thirty plant species have been studied, of which 80 substances have been 
isolated, including 7 new natural compounds. Establishment of the structure and 
identification of isolated substances was carried out using modern physical and 
chemical methods (UV-, IR-, 
1
H and 
13
C NMR spectroscopy and X-ray diffraction 
analysis). 
The results of the ongoing research expand the field of fundamental knowledge about 
terpenoids and phenolic compounds of plants of the flora of Uzbekistan and will serve 
as a scientific basis for the creation of new effective natural preparations for medicine 
and the national economy. 
References: 
1.
R.M. Mukhamatkhanova, D.E. Dusmatova, I.D.Sham`yanov. Terpenoids of 
Inula
L. Genus Plants. In book: Terpenes and Terpenoids: Sources, Applications and 
Biological Significance. Ed. Ch.A. Davies. Nova Science Publishers, USA, New York, 
2022. Series: 
Biochemistry Research Trends.
– P. 1-69. 
2.
D. E. Dusmatova, Kh. М. Bobakulov, K. K. Turgunov, R. F. Мukhamatkhanova, 
V. V. Uzbekov, H. Gildenast, U. Englert, I. D. Sham’yanov, B. Tashkhojaev, V. P.
Bruskov, N. D. Аbdullaev. Guaianolides from 
Tanacetopsis karataviensis.
Nat. Prod. 
Res., 
2022, V. 36, Pp. 1734-1740.
3.
U. Babekov, N. M. Yuldasheva, A. M. Ismailova, B. Dzh. Komilov, K. K. 
Turgunov, B. Tashkhodzhaev, and K. A. Eshbakova. Terpenoids from the plant 
Ferula 
ferganensis. Chem. Nat. Compd.,
2022,