FLAVONOIDS OF THE AERIAL PART OF Perovskia angustifolia O. K. Askarova 1 , A. A. Ganiev 2 , Kh. M. Bobakulov 2 , D. R. Siddikov 2 , E. Kh. Botirov 2 1) Namangan Institute of Engineering and Technology, Namangan, Uzbekistan 2) S.Yu.Yunusov Institute of the Chemistry of Plant Substance, Academy of Science of the Republic of Uzbekistan, e-mail: botirov-nepi@mail.ru
The genus
Perovskia Kar. belongs to the clover berry family (Lamiacaeae). It
includes 9 species of semi-shrubs, most of which (7 species) grow wild in mountainous
areas of Central Asia, including four species in Uzbekistan [1].
Perovskia angustifolia Kudr is a honeybee and perganosum that grows in Tashkent, Samarkand, Surkhandarya,
and the Fergana Valley. The decoction of the leaves is used as an antihelminthic agent,
and infusion and tincture have an antibacterial and wound healing effect, a short-term
decrease in blood pressure, and an increase in heart rate. Leaf extract has anthelmintic
activity and is used for skin diseases, stomach disorders, and as a diuretic. Caffeic (
1 )
and rosmarinic (
2 ) acids were isolated from an alcoholic extract of the air-dried above-
ground part of the plant collected on the territory of the Namangan region (Kamchik
pass) of the Republic of Uzbekistan during flowering (June 2021), as well as flavones
apigenin (
3 ), luteolin (
4 ), diosmetin (
5 ), cirsimaritin (
6 ), flavanones neoponcirin (
7 ),
hesperidin (
8 ), hesperetin (
9 ) and flavanonol derivative taxifolin (
10 ).
Identification of isolated compounds was performed by studying their spectral data
of UV, 1H and 13C NMR, as well as by HSQC and HMBC experiments followed by
comparison with literature data.
The above compounds were isolated from P. angustifolia for the first time.
Reference 1. Mohammadhosseini M., Venditti A., Akbarzadeh A. The genus Perovskia Kar.:
ethnobotany, chemotaxonomy and phytochemistry: a review. Toxin Reviews. 2021. V.
40 (4). Pp. 484-505.