|
Author
Year,
reference
Country
Sample, n
Age (yrs)
at start
Teeth
tested
Caries
preval-
ence at
start
Obs
Time
(yrs)
Drop-
out (%)
Ex-
plained
Diag-
nostic
criteria
Exam-
iner (n)
Relia-
bility
Predictor
variables
Validating
criteria
Statistical
methods
Results
Caries rates
Survival time
Relative risk (RR)
Study
quality and
relevance
Comments
Mejàre et al
2004 [2]
Sweden
534
12–13 years
All children
from a com-
munity south
of Stockholm
with mixed
socioeconomy
Occlu-
sal and
approximal
surfaces
Radio-
graphic
study
Mean
DMFT at
start: 3.2
Mean DFS
approximal:
0.6
15
31
Ex-
plained
No dif-
ference
in base-
line DFS
or DS
between
those
lost and
those
followed
Own
criteria
(radio-
graphic)
2 exam-
iners
Yes
Post-eruptive age:
Age groups 12–15,
16–19 and 20–27
Sound to
enamel,
enamel to
dentine,
in dentine,
sound to
dentine
Incidence
(caries
rate=number
of new
lesions/100
tooth-sur-
face-years)
Survival
analysis
Caries rates, Sound
to dentine for all
teeth
12–15 yrs: 2.0
16–19 yrs : 0.9
20–27 yrs: 0.7
Occlusal surfaces,
1st molars
12–15 yrs: 4.4
16–19 yrs: 2.3
20–27 yrs: 1.5
Occlusal surfaces,
2nd molars
12–15 yrs: 6.7
16–19 yrs: 3.0
20–27 yrs: 2.7
High
K A R I E S – d I A G N O S T I K , R I S K B E d ö M N I N G O C H I C K E - I N vA S I v B E H A N d L I N G
298
Table 5.9 Post-eruptive age as risk factor. Studies with low quality and/or relevance.
Author
Year,
reference
Country
Sample, n
Age (yrs)
at start
Teeth
tested
Caries
preval-
ence at
start
Obs
time
(yrs)
Drop-out
(%)
Diag-
nostic
criteria
Ex-
plained
Exam-
iner (n)
Relia-
bility
Predictor
variables
Validating
criteria
Statist-
ical met-
hods
Results
Caries rates
Survival time
Relative risk (RR)
Study
quality and
relevance
Comments
Carlos et al
1965 [49]
USA
5 068
4–18 years
Children and
adolescents in
Kingston, NY
taking part in
a prevention
programme
All perma-
nent teeth
6
25
Explained
Not
repor-
ted
No BW
Not
reported
Post-eruptive age:
1–6 years after
tooth eruption
Dentine/
cavity
Life table
analysis
Caries incidence
was highest during
the first 3–4 yrs
after tooth eruption.
Most pronounced
for 1st and 2nd
molars
Low
Heterogen-
eous sample.
Population
not exposed
to fluoride
toothpaste
Månsson
1977 [50]
Sweden
169
5–6 years
All children
belonging to 3
school districts
in Umeå
taking part in
a prevention
programme
(mouth rinsing
1/week)
Occlusal
surfaces of
permanent
1st molars
Mean dmft
in primary
teeth not
stated
27
months
33
Explained
Möller
1966
No BW
Not
stated
Post-eruptive age:
Examination at 3,
6, 9, 12, 15, 18, 21,
27 months after
tooth eruption
Dentine/
cavity
Life table
analysis
(made
from
reported
data)
41% of the molars
were caries-free
at the end.
25% of the children
had no decayed
molars at the end.
Probability of
remaining caries-
free at the end of
period (months)
3: 0.92
6: 0.80
9: 0.66
12: 0.57
15: 0.49
18: 0.45
21: 0.42
27: 0.41
Low
No reprodu-
cibility test
299
K A P I T E L 5 • r I s K b E d ö M n I n g
Table 5.9 Post-eruptive age as risk factor. Studies with low quality and/or relevance.
Author
Year,
reference
Country
Sample, n
Age (yrs)
at start
Teeth
tested
Caries
preval-
ence at
start
Obs
time
(yrs)
Drop-out
(%)
Diag-
nostic
criteria
Ex-
plained
Exam-
iner (n)
Relia-
bility
Predictor
variables
Validating
criteria
Statist-
ical met-
hods
Results
Caries rates
Survival time
Relative risk (RR)
Study
quality and
relevance
Comments
Carlos et al
1965 [49]
USA
5 068
4–18 years
Children and
adolescents in
Kingston, NY
taking part in
a prevention
programme
All perma-
nent teeth
6
25
Explained
Not
repor-
ted
No BW
Not
reported
Post-eruptive age:
1–6 years after
tooth eruption
Dentine/
cavity
Life table
analysis
Caries incidence
was highest during
the first 3–4 yrs
after tooth eruption.
Most pronounced
for 1st and 2nd
molars
Low
Heterogen-
eous sample.
Population
not exposed
to fluoride
toothpaste
Månsson
1977 [50]
Sweden
169
5–6 years
All children
belonging to 3
school districts
in Umeå
taking part in
a prevention
programme
(mouth rinsing
1/week)
Occlusal
surfaces of
permanent
1st molars
Mean dmft
in primary
teeth not
stated
27
months
33
Explained
Möller
1966
No BW
Not
stated
Post-eruptive age:
Examination at 3,
6, 9, 12, 15, 18, 21,
27 months after
tooth eruption
Dentine/
cavity
Life table
analysis
(made
from
reported
data)
41% of the molars
were caries-free
at the end.
25% of the children
had no decayed
molars at the end.
Probability of
remaining caries-
free at the end of
period (months)
3: 0.92
6: 0.80
9: 0.66
12: 0.57
15: 0.49
18: 0.45
21: 0.42
27: 0.41
Low
No reprodu-
cibility test
The table continues on the next page
K A R I E S – d I A G N O S T I K , R I S K B E d ö M N I N G O C H I C K E - I N vA S I v B E H A N d L I N G
300
Table 5.9 continued
Author
Year,
reference
Country
Sample, n
Age (yrs)
at start
Teeth
tested
Caries
preval-
ence at
start
Obs
time
(yrs)
Drop-out
(%)
Diag-
nostic
criteria
Ex-
plained
Exam-
iner (n)
Relia-
bility
Predictor
variables
Validating
criteria
Statist-
ical met-
hods
Results
Caries rates
Survival time
Relative risk (RR)
Study
quality and
relevance
Comments
Shwartz
et al 1984
[51]
Sweden, USA
758
10–11, 17–18
and 21–22 yrs
at the end of
study.
Mixed popu-
lation from
Sweden and
US; Swedish
population
a cohort,
US part of a
prevention
programme
on topical
application
of fluoride
Approxi-
mal sur-
faces
Radio-
graphic
study
Mean DFS
at start
Swed (US)
Age 11:
6.6 (8.5)
Age 17:
7.9 (8.0)
Age 21–22:
13.6
4
Not
stated
Own
criteria
(radio-
graphic)
No of
exam-
iners
unclear
Not
stated
Post-eruptive
age: 7–11,
12–16, 17–22
Sound
to outer
enamel,
outer
enamel
to inner
enamel
Survival
analysis
Mean survival time
in months; Sweden
(USA)
Sound to enamel,
age at end
10–11 yrs: 21 (23)
17–18 yrs: 38 (16)
21–22 yrs: 41
Outer to inner
enamel, age at end
10–11 yrs: 28 (19)
17–18 yrs: 47 (27)
21–22 yrs: 56
For Swedish group
mean survival time,
in years
Through whole
enamel, age at end
10–11 yrs: 4
17–18 yrs: 7
21–22 yrs: 8
Low
BW = Bitewing; DFS = Decayed, filled surfaces (permanent teeth);
dmft = Decayed, missing, filled teeth (primary teeth)
301
K A P I T E L 5 • r I s K b E d ö M n I n g
Table 5.9 continued
Author
Year,
reference
Country
Sample, n
Age (yrs)
at start
Teeth
tested
Caries
preval-
ence at
start
Obs
time
(yrs)
Drop-out
(%)
Diag-
nostic
criteria
Ex-
plained
Exam-
iner (n)
Relia-
bility
Predictor
variables
Validating
criteria
Statist-
ical met-
hods
Results
Caries rates
Survival time
Relative risk (RR)
Study
quality and
relevance
Comments
Shwartz
et al 1984
[51]
Sweden, USA
758
10–11, 17–18
and 21–22 yrs
at the end of
study.
Mixed popu-
lation from
Sweden and
US; Swedish
population
a cohort,
US part of a
prevention
programme
on topical
application
of fluoride
Approxi-
mal sur-
faces
Radio-
graphic
study
Mean DFS
at start
Swed (US)
Age 11:
6.6 (8.5)
Age 17:
7.9 (8.0)
Age 21–22:
13.6
4
Not
stated
Own
criteria
(radio-
graphic)
No of
exam-
iners
unclear
Not
stated
Post-eruptive
age: 7–11,
12–16, 17–22
Sound
to outer
enamel,
outer
enamel
to inner
enamel
Survival
analysis
Mean survival time
in months; Sweden
(USA)
Sound to enamel,
age at end
10–11 yrs: 21 (23)
17–18 yrs: 38 (16)
21–22 yrs: 41
Outer to inner
enamel, age at end
10–11 yrs: 28 (19)
17–18 yrs: 47 (27)
21–22 yrs: 56
For Swedish group
mean survival time,
in years
Through whole
enamel, age at end
10–11 yrs: 4
17–18 yrs: 7
21–22 yrs: 8
Low
K A R I E S – d I A G N O S T I K , R I S K B E d ö M N I N G O C H I C K E - I N vA S I v B E H A N d L I N G
302
Author, year, reference
Main reason for exclusion
Children and adolescents
Aaltonen et al, 2000 [91]
Not prediction
Aaltonen et al, 1994 [92]
Only correlation
Alaluusua et al, 1983 [93]
Too small sample (n=39)
Alanen et al, 1994 [94]
Too short follow-up time
Anderson, 2002 [95]
Narrative review
Ashley et al, 1981 [96]
Not prediction
al-Shalan et al, 1997 [97]
Retrospective data
Bader et al, 2004 [98]
Review on prevention
Bader et al, 1986 [99]
Too short follow-up (18 months)
Bader et al, 2005 [100]
Predicting restorative treatment only
Bawden et al, 1980 [101]
Effect of programme
Benn et al, 1997 [102]
Not answering the question
Bergman et al, 1986 [103]
Cross-sectional study
Berkey et al, 1991 [104]
Narrative review
Bille, 1980 [105]
Modelling data
Birkeland et al, 1976 [106]
Only associations
Bjerkeborn et al, 1987 [107]
Cross-sectional study
Botha et al, 2001 [108]
Cross-sectional study
Bratthall, 1997 [109]
Narrative article
Burt et al, 1983 [110]
Longitudinal but only associations
Burt et al, 1988 [111]
Longitudinal but only relationships
Burt, 1993 [112]
Narrative review
Burt, 2005 [8]
Review of concepts of risk
Campus et al, 1997 [113]
Cross-sectional study
Campus et al, 2000 [114]
Cross-sectional study
Campus et al, 2001 [115]
Cross-sectional study
Carvalho et al, 1989 [116]
Cross-sectional study
Caufield et al, 1993 [117]
Not prediction
Chase et al, 2004 [118]
Correlations only
Cleaton-Jones et al, 1991 [119]
Cross-sectional study
Crossner, 1981 [120]
Too short follow-up (15 months)
Table 5.10 Excluded studies.
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303
K A P I T E L 5 • r I s K b E d ö M n I n g
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Author, year, reference
Main reason for exclusion
Demers et al, 1990 [121]
Narrative review
Disney et al, 1992 [122]
Not prediction
Dodds et al, 1995 [123]
Narrative review
Douglass, 1998 [124]
Methodology
Downer, 1978 [125]
Correlations only
Downer, 1978 [126]
Narrative review
Drake et al, 1994 [127]
Too short follow-up (18 months)
Dummer et al, 1990 [128]
Covariance analysis, not prediction
Ekstrand et al, 1998 [129]
Only associations
Erickson et al, 1999 [130]
In vitro study
Frencken et al, 1992 [131]
Not prediction
Federation Dentaire Internationale
1988 [132]
Narrative review
Fyffe et al, 2000 [133]
Not prediction
Granath et al, 1978 [134]
Not prediction
Granath et al, 1978 [135]
Modelling data
Graves et al, 1991 [136]
Not prediction
Graves, et al, 1990 [137]
Narrative review
Grindefjord et al, 1995 [138]
Cross-sectional analysis
Grytten et al, 1988 [139]
Only associations calculated
Habibian et al, 2001 [140]
Caries not outcome measure
Helfenstein et al, 1991 [141]
Statistical modelling of data
Heller et al, 2000 [142]
Outcome measure = treatment
Helm et al, 1990 [143]
Correlations only
Hill et al, 1967 [144]
Not applicable (before fluor toothpaste
was introduced)
Hintze, 1997 [145]
Retrospective, serious systematic bias likely
Holbrook et al, 1995 [146]
Bivariate associations only
Holst et al, 1997 [147]
Diagnostic criteria not described
Honkala et al, 1984 [148]
Cross-sectional study
Hunter, 1988 [149]
Narrative review
Hujoel et al, 1995 [150]
Not prediction
Hujoel et al, 1999 [151]
Not prediction
The table continues on the next page
Table 5.10 continued
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304
Author, year, reference
Main reason for exclusion
Hänsel Petersson et al, 2004 [152]
Not prediction
Imfeld et al, 1995 [153]
Not answering the question
Isokangas et al, 1993 [154]
Pilot study, heterogeneous sample
Jaafar et al, 1988 [155]
Correlations only
Kawabata et al, 1997 [156]
Model applied backwards
Kidd, 1998 [157]
Not answering the question
Kingman et al, 1988 [158]
Too short follow-up time (17 months)
Kirchner et al, 1991 [159]
Not prediction
Klein et al, 1981 [160]
Correlation analysis only
Klock et al, 1979 [161]
Correlation analysis only
Klock et al, 1989 [162]
Too short follow-up (12 months)
Kolehmainen et al, 1985 [163]
Too short follow-up (12 months)
Krasse, 1988 [164]
Narrative review
Kristoffersson et al, 1985 [165]
Too small sample (n=28)
Kronmiller et al, 1988 [166]
Prevalence data
Källestål et al, 2000 [167]
Not prediction
König, 1963 [168]
In vitro study
Köhler et al, 1988 [169]
Associations only
Lai et al, 1997 [170]
Too small sample (25 x 2)
Lawrence et al, 1997 [171]
Not prediction. 1 year follow-up only
Leverett et al, 1993 [172]
Too short follow-up (6 months)
Leverett et al, 1993 [173]
Cross-sectional study
Litt et al, 1995 [174]
Correlation analysis only
Locker, 1998 [175]
Not prediction
Lu, 1966 [176]
Not answering the question
MacEntee, 1994 [177]
Narrative review
MacKeown et al, 2003 [178]
Associations only
Mancl et al, 2004 [179]
Methodology
Margolis et al, 1994 [180]
Prevalence data
Mariri et al, 2003 [181]
Case-control study
Matejka et al, 1989 [182]
Associations only
Meldrum et al, 2001 [183]
Only associations described
Mejàre et al, 2000 [184]
Surface risk assessment
Table 5.10 continued
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K A P I T E L 5 • r I s K b E d ö M n I n g
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