Anahtar Kelimeler: Ağrı Fizyopatolojisi, Glutamat, P
maddesi.
Abstract
Pain is a signal to the protection given by the body, in
fact giving people uncomfortable lives. The process
in pain physiology begins with the activation of spe-
cific receptors, called nociceptors, by stimuli, which
can cause pain. Aδ fibers are fast; C fibers carry a
slow pain stimulus and the sensation of pain does
not occur until the cortex is responsible for the for-
mation of emotional and cognitive pain. Neuropathic
pain, which is present in the classification of pain and
constitutes an important disease population, occurs in
the damage or dysfunction of the peripheral or central
nervous system. Pain is often flammable, sharp, and
sometimes it describe as electrical shock. Sometimes
it is necessary to know the concept of memory in the
pain that occurs without mentioning the presence of
the stimuling. The work of our pain memory is the re-
sult of changes in receptors. Recent understanding
of the physiological and chemical mechanisms in-
volved in pain has made significant improvements in
pain management It is important for researchers to
identify the receptor and transmitter relationship that
will lead to new treatments. Improving and refining
our knowledge about pain physiopathology can be a
basis for presenting effective and reliable treatments
that increase the quality of life of human beings with
the technological elements that develop in clinical and
research.
Keywords: Pain Physiopathology, Glutamate, Subs-
tance P.
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