particularly isolated systolic hypertension"
and
"Overview of secondary prevention of
ischemic stroke"
.)
The authors suggestions for goal blood pressure are as follows, and depend upon the
patient’s baseline risk of having a cardiovascular event; these suggestions broadly agree
with those recommendations made by the 2017 ACC/AHA guidelines but contrast with
other guidelines (see
"Goal blood pressure in adults with hypertension", section on
'Recommendations of others'
) [
4
]:
Once blood pressure goal is determined in an individual patient, it should be recorded in
the patient’s medical record, explicitly explained to the patient, and communicated to other
The authors suggest a goal blood pressure of <130 mmHg systolic and <80 mmHg
diastolic using out-of-office measurements (or, if out-of-office blood pressure is not
available, then an average of appropriately measured office readings) in most patients
who qualify for antihypertensive pharmacologic therapy. Identifying patients for
initiation of antihypertensive drug therapy is presented above. (See
'Who should be
treated with pharmacologic therapy?'
above.)
●
However, there is some disagreement among UpToDate authors and editors. Some
believe that, among selected hypertensive patients who qualify for antihypertensive
therapy but who are at low absolute cardiovascular risk, a less aggressive goal blood
pressure of <135 mmHg systolic and <85 mmHg diastolic (using out-of-office
measurement) or <140 mmHg systolic and <90 mmHg diastolic (using an average of
appropriately measured office readings) is appropriate.
We suggest a less aggressive goal blood pressure of <135 mmHg systolic and <85
mmHg diastolic (using out-of-office measurement) or <140 mmHg systolic and <90
mmHg diastolic (using an average of appropriately measured office readings) in the
following groups of hypertensive patients:
●
Patients with labile blood pressure or postural hypotension
•
Patients with side effects to multiple antihypertensive medications
•
Patients 75 years or older with a high burden of comorbidity or a diastolic blood
pressure <55 mmHg
•
In older adults with severe frailty, dementia, and/or a limited life expectancy, or in
patients who are non-ambulatory or institutionalized (eg, reside in a skilled nursing
facility), we individualize goals and share decision-making with the patient, relatives,
and caretakers, rather than targeting one of the blood pressure goals mentioned
above.
●
members of the health care team. At every visit, a determination should be made as to
whether or not blood pressure is at goal.
After antihypertensive therapy is initiated, patients should be re-evaluated and therapy
should be increased monthly until adequate blood pressure control is achieved [
4
]. Once
blood pressure control is achieved, patients should be reevaluated every three to six
months to ensure maintenance of control [
4
].
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