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P. Tiyas, P. Pooja, Sh. Abha.
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S.A. Amin, S. Banerjee, S. Singh,
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N
N
O
AG
(AG - Aminoglycoside)
BE = -11.68 kcal/mol
Poster presentation
174
PLANT Physalis alkekengi
Z.A. Kadirova, Sh.S. Tаshmukhamedova, Sh.N. Mingnorov,
M.T. Saidova, D.K. Khojiyeva
National University of Uzbekistan named after M. Ulugbek,
e-mail: zukhra_abrarovna7@mail.ru
Physalis alkekengi
from the Solanaceae family is characterized by a rich composition
of biologically active substances (biologically active substances), that is, chemical
substances with high physiological activity at low concentrations relative to the living
organism. Among the biologically active substances synthesized and accumulated by
the plant are alkaloids, steroids, flavonoids, carotenoids, polysaccharides, lectins,
pectins, vitamins, fatty oils, tannins (tannins), etc. The purpose of the research is
Physalis alkekengi
is to choose the optimal conditions for extracting flavonoids from
the plant and to determine the flavonoid content in the dry extract.
Research materials and methods: in the study, ethanol was used in concentrations
from 40 to 90% to separate flavonoids. The obtained mass was dried in a lyophilic dryer
using liquid nitrogen. The content of flavonoids in the obtained dry extracts was
determined in relation to luteolin. Quantification of flavonoids was carried out in a
spectrophotometer.
Discussion results: the effect of some factors on the release of flavonoids, namely the
concentration of the extractant, the particle size of the raw material, the effect of the
incubation time and the ratio of the raw material to the extractant in the study on the
selection of optimal conditions for the extraction of flavonoids from
Physalis alkekengi
was studied. The effect of extractant (ethanol) concentration was studied to determine
the completeness of flavonoid extraction from the plant, and at low concentrations
(20%, 30% and 40%) flavonoid release ranged from 0.25 to 0.55 mg It was found that
flavonoids were completely extracted by ethanol at a concentration of 80%. In this case,
the flavonoid concentration was 1.92 mg. A further increase in the concentration of the
extract did not lead to an increase in the extraction efficiency of flavonoids. The
extraction time of flavonoids from 30 to 135 minutes of incubation time flavonoidl
within 105 minutes while studying the effect on efficiency It was determined that ar can
be completely obtained from plant materials. When choosing the degree of grinding, the
diameter of plant holes is 0.5; 1.0; 2.0; 3.0; They used 4.0 and 5.0 mm raw material
particles. From the obtained data, it is known that the maximum extraction of flavonoids
from the plant is achieved by grinding the raw material to a particle size of 2.0 mm. is
carried out (the number of flavonoids is 1.93 mg).
Conclusion: A method of extracting dry extract and flavonoid content from the plant
Physalis alkekengi
was developed. The methods of obtaining biologically active
substances of the medicinal plant
Physalis alkekengi
were analyzed. The optimal
conditions for obtaining flavonoids of the studied object were selected. 80% ethyl
alcohol with 0 mm raw material particles was optimal for the extraction of flavonoids,
and the raw material: extractant ratio was 1:100, and the extraction time was 105
minutes.
Poster presentation
175
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