Poster presentation
253
NITRATION REACTIONS OF QUINOLINE ALKALOIDS
ANHYDROPERFORINE AND HAPLOPHYLIDINE
А.U. Ubaydullaev
1
, Sh.N. Zhurakulov
1,2
, V.I. Vinogradova
1
, K.K. Turgunov
1,3
1) S.Yu. Yunusov Institute of the Chemistry of Plant Substances Academy of sciences of
the Republic of Uzbekistan st. Mirzo-Ulugbek, 77, 100170 Tashkent
2) National University of Uzbekistan named after Mirzo Ulugbek,
3) Turin polytechnic University in Tashkent, Tashkent 100095 Uzbekistan.
e-mail: ubaydullayev-aziz@mail.ru
Quinoline alkaloids are of particular importance due to their unique medicinal
properties and being added as additives to drugs against many diseases. For example:
Quinine and Quinacrine are used effectively to treat the parasites that cause malaria.
Carteolol is used to treat arrhythmia and glaucoma. Rosoxacin is used in the treatment
of respiratory tract, urinary tract, gastrointestinal tract, central nervous system and
bacterial infections. Considering these properties of quinoline alkaloids, nitration
reactions of anhydroperforin and haplophyllidine alkaloids synthesized on the basis of
haplophyllidine alkaloid isolated from the seeds of
Haplophyllum perforatum
plant
were carried out in two methods.
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